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        응급 수술을 시행한 신경외상 환자들에 있어 전염성 바이러스 감염의 유병율에 대한 분석

        남경협 ( Kyoung Hyup Nam ),최혁진 ( Hyuk Jin Choi ),이재일 ( Jae Il Lee ),고준경 ( Jun Kyeung Ko ),한인호 ( In Ho Han ),조원호 ( Won Ho Cho ) 대한외상학회 2015 大韓外傷學會誌 Vol.28 No.1

        Purpose: The aim of this study was to estimate the seropositive prevalence of blood-borne infection in neurotrauma patients who underwent emergent surgical intervention, especially patients with hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis and human immunodefIciency virus (HIV). Methods: A retrospective review identified 559 patients with traumatic brain injury and spinal trauma who underwent emergent surgery between 2007 and 2014. We reviewed the medical records and extracted data, including age, sex, location of lesion, result of serologic tests, time interval of admission and surgery after presenting to emergency room. Serologic tests for HBV, HCV, syphilis and HIV were performed and analyzed to determine whether the seropositive results were confirmed by the surgeon before surgery. Results: The majority of the patients were male (74.6%), and the mean age was 55.4±20.2 years. Most patients underwent surgery due to traumatic brain injury (90.0%). Fifty-three patients (10.0%) showed a positive result on at least one serologic test. Seropositive rates according to pathogens were 0.5% for syphilis, 5.2% for HBV and 3.9% for HCV. No positive results were noted on the serologic tests for HIV. HBV in patients with spinal cord injury and age from 40 to 49 years were associated with high serologic positive rate, and that result was statistically significant. However, no statistically significant differences were found in the other variables. Serologic results could not confirmed before surgery in the majority of the cases (62.1%), and 10.4% of these patients showed seropositive results. Conclusion: The results of this study emphasize the importance of taking precautions and conducting rapid serologic testing in preventing the occupational transmission of blood-borne viruses to health-care workers. [ J Trauma Inj 2015; 28: 9-14 ]

      • 례뇌하수체 선종과 동반되어 안상조에 발생한 지주막 낭종

        남경협 ( Kyoung Hyup Nam ),차승헌 ( Seung Heon Cha ),조원호 ( Won Ho Cho ),최병관 ( Byung Kwan Choi ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2012 대한뇌종양학회지 Vol.11 No.1

        Objectives: Arachnoid cysts are a relatively rare pathological entity, and a suprasellar arachnoid cyst is quite rare. We report on an extremely rare case of a suprasellar arachnoid cyst associated pituitary adenoma and discuss the possible pathogenesis. Clinical Presentation: A 24-year-old man was admitted to the hospital with a history of headache, visual field defect, gait disturbance, syncope, and urinary incontinence. Computed tomography showed severe hydrocephalus. Preoperative magnetic resonance images revealed a mass lesion in the sella turcica with suprasellar extension and a coexisting large supra- and parasellar cyst. Transcranial surgery was performed for the removal of the tumor mass and cyst. Ventricle size normalized after the operation. He exhibited an uneventful recovery without neurologic deficits or endocrinologic abnor-malities. Conclusion: We present clinical, radiological, and histopathological findings and discuss the possible pathogenesis of a suprasellar arachnoid cyst associated pituitary adenoma.

      • 임상 : 상두개강내에 상의 세포종의 임상적 결과와 여후 인자

        이수헌 ( Su Heon Lee ),차승헌 ( Seung Heon Cha ),남경협 ( Kyoung Hyup Nam ),조원호 ( Won Ho Cho ) 대한뇌종양학회 2012 대한뇌종양학회지 Vol.11 No.1

        Objective: Ependymomas are infrequently seen tumors that have been defined as neoplasm arising from ependymal cells lining the ventricles and the central canal of the spinal cord. As prognostic factor, histological features and surgical resection and the efficacy of prophylactic radiation remain controversial in the management of intracranial ependymoma. We analyzed a series of patients with intracranial ependymoma to review our strategy of treatment and prognostic factor. Materials and Methods: Between Jan 2001 and Dec 2008, 11 patients have been under treatment at our institute. Seven cases involved Grade II lesion according to the World Health Organization (WHO) classification of ependymoma, and four cases involved Grade III lesion. Postoperative radiation was performed in eight cases and chemotherapy was administered in three childhood patients. We analyzed the result of treatment and prognosis according to recurrence of tumor. Results: Overall recurrence rates were significantly lower in patients with Grade II ependymoma and in patients who had undergone gross total resection of the tumor. Three patients (27.3%) revealed progression or recurrence from 12 to 65 months (median 29.7 months) after diagnosis. In two patients, the ependymoma recurred only at the original tumor site. One patients experienced both local and distant relapse as spinal seeding. Histologic grade and extent of resection were related with tumor recurrence or progression. Among eight cases underwent adjuvant radiotherapy (Five cases of Grade II, Three cases of Grade III), three cases of Grade III revealed tumor progression and none of Grade II cases showed tumor progression. Conclusion: Histologic grade is the important prognostic factor with respect to patient survival, tumor recurrence and tumor progression. Although there was no statistical significance, progression rate is higher in young age and infratentorial tumors. Grade III ependymoma is more common in young age and infratentorial area.

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