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나대웅(Dae-Woong Na),정은(Eun Jeong),노은경(Eun-Kyung Noh),정지숙(Ji-Sook Chung),최천호(Cheon-Ho Choi),박종(Jong Park) 한국농촌의학 지역보건학회 2010 농촌의학·지역보건 Vol.35 No.4
본 연구는 국민건강영양조사 제4기 1차년도(2007년)의 자료를 이용하여 우리나라 40세~64세 중장년 남성의 대사증후군 유병률을 파악하고 영양소 섭취량 등의 식이 요인과 대사증후군과의 관련성을 파악하고자 시행되었다. 성인 남성 709명 중 설문조사, 건강 검진, 영양조사의 연관성 가중치가 제공되지 않은 경우와 설문에 대한 불충분한 응답으로 대사증후군 여부를 평가할 수 없는 348명을 제외한 총 361명을 최종 분석 대상자로 하였다. 대사증후군의 정의는 2004년에 개정된 NCEP ATP III을 기준으로 하였고, 복부비만 항목은 아시아-태평양 비만치료지침의 기준을 사용하였다. 대사증후군의 유병률은 40-49세 26.0%, 50-59세 30.4%, 60-64세 54.5%로 나타났으며, 대사증후군의 구성요소 중 복부비만과 혈당치는 연령에 따라 유의한 차이를 보였다. 대사증군군과 유의한 관련을 보인 변수는 연령, 총흡연량, 외식 횟수였으며 에너지, 나트륨, 리보플라빈, 탄수화물, 단백질, 지방, 무기질 섭취량 등의 식이요인은 유의한 관련이 없었다. 결론적으로 한국 중년 남성에 있어서는 식이습관 중 외식 횟수가 대사증후군과 유의한 관련이 있어 이를 감소하고 개선시키기 위한 효율적인 중재가 필요하다고 생각한다. 본 연구에서 영양소 섭취량은 대사증후군과 유의한 관련이 없었지만 이 부분에 대한 세밀하고 추가적인 향후 연구가 필요할 것으로 사료된다. Objectives: This study aims to identify dietary factors related to metabolic syndrome in middle aged Korean men who were participants in the Fourth Korea National Health and Nutrition Examination Survey(KNHANES IV) in 2007. Methods: The study targeted 361 of the 709 men aged between 40 and 64 years for a final analysis; the other 348 surveys had incomplete data which did not allow for the determination of metabolic syndrome. The definition of metabolic syndrome was based on the National Cholesterol Education Program Adult Treatment Panel Ⅲ(NCEP ATP Ⅲ). Results: There were significant differences in the metabolic syndrome of middle-aged men according to age, smoking pack-years, and number of resturant meals per week. Dietary factors such as vitamins, riboflavin, natrium, carbohydrate, protein and lipid intakes were not significant. Conclusions: It was verified that metabolic syndrome in middle-aged men is related to age, smoking pack-years and number of resturant meals per week. Dietary factors were not significantly related. However, further detailed studies in this area are needed.
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정지숙 ( Ji Sook Chung ),박형수 ( Hyung Su Park ),나대웅 ( Dae Woong Na ),노은경 ( Eun Kyung Noh ),최천호 ( Cheon Ho Choi ),박종 ( Jong Park ) 대한예방치과·구강보건학회 2010 大韓口腔保健學會誌 Vol.34 No.4
Objectives. The purpose of this research was to examine the prevalence of halitosis in Korean adolescents and determine relative causes. Methods. The subjects of the study were 74,698 adolescents, they were middle school to high school students who completed the 2007 Korea Youth Risk Behavior survey. Results. The odds ratios for developing halitosis were low for male students who live in large cities who considered themselves to be healthy, and who brushed their teeth more than 3 times a day. However, the odds ratios for those who considered themselves to be overweight and who had low financial status were significantly lower. The odds ratios were significantly lower for those who had much stress, low grades in their studies, and had dental disease over 3 times for one year. For female students, those who had a low financial status and dental disease over 3 times for one year showed a significantly higher odds ratio of 7.53. Subjects who were drinking and smoking at that time, who had a normal figure, and who brushed their teeth over 3 times a day had a significantly lower odds ratio. Conclusions. This study has identified the current statusof halitosis in Korean adolescents and the relevant causes. It is suggested that they learn how to brush their teeth properly to prevent halitosis.
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핵산유도체와 전구물질들의 항 Herpes바이러스 In Vitro 약효평가
이종교,나지숙,김해수 대한바이러스학회 1992 Journal of Bacteriology and Virology Vol.22 No.1
To evaluate in vitro anti herpetic efficacy of nucleoside analogues and precursor (base) analogues, Vero cells were infected with three different strains of HSV-1 and 2 of HSV-1 and 2 of HSV-2 and treated with the compounds. The antiviral activity was evaluated by virus-induced cytopathic effect(CPE) inhibition assay. Anti-CMV activity was measured by CPE inhibition assay and anti-VZV by plaque reduction assay. HEL 299 cells were used for the replication of CMV and VZV. VZV showed generally the highest sensitivity against tested compounds followed by HSV and CMV. There was no significant difference between anti-HSV-1 and anti HSV 2 activity of tested compounds except BVdUrd and TFT. But differences among strains of the same virus were rather observed. All compounds licensed for the clinical treatment, ACV, Ara A, IdUrd, TFT, GCV and PFA, showed in vitro efficacy against their target viruses. Cytostatic and cytocidal effects of the compounds were also measured by MTT assay in Vero cell cultures. The former were more significant than the latter.
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