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Propyl gallate에 의한 알레르기성 접촉 구순염
이지호,윤두희,이준영,김형옥 ( Ji Ho Lee,Doo Hee Yoon,Jun Young Lee,Hyung Ok Kim ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.2
Propyl gallste and other gallic acid esters are used as antioxidants in lipsticks, lip balms and salves, cosmetic creams and lotions, bakery products, edible fats and other pharmaceutical and industrial products. Propyl gallate is used widely but allergic contact dermatits from propyl gallate is rare. A 44-year-old female patient had pruritic multiple tiny erythematous papules and vesicles on the margin of her lip for a week. We found that the causative material of the allergic contact cheilitis was propyl gallate. We proved it with a patch test, provocation use test and quantitative and qualitative analysis of the lipstick. To our knowledge, this is the first case report of lipstick allergic contact cheilitis from propyl gallate in Korean literature. (Kor J Dermatol 1997;35(2): 374-378)
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이지호,채규태,최성우,김형옥,김대호,김태윤 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.3
Backgroud: There were no effective methods to monitor the treatment of leprosy. Anti-PGL-1 ELISA test and polymerase chain reaction (PCR) were used for monitoring the treatment, however many restrictions have been found to apply to those methods in the field. Bacillary index (BI) is a popular and not an expensive method. For this reason, the exact data to assess the efficacy of the standard multi-drug therapy (MDT) with BI is required for evaluation of the treatment in Korea. Objective: The purpose of this study was to clarify the change of bacillary index during MDT in multi-bacillary leprosy (MB) cases. Methods: A total of 72 patients in the National Sorokdo Hospital were included in this study. With the retrospective method, BI, type of leprosy, relapse, age, and duration of treatment were evaluated. Results : The results were as follows; 1.In this study, the mean duration of BI changing from 6 to 5 was 5.7 months, from 5 to 4 was 6.6 months, from 4 to 3 was 13.1 months, from 3 to 2 was 13.8 months, from 2 to I was 12.4 months, from 1 to 0 was 29.4 months. 2. The time of initial change of BI after MDT were as follows : within 3 months(26.4%), 4-6 months(29.2%), 7-12 months(26.4%), 13-18 months(8.3%), 19-24 months(4.2%), 25-48 months(5.5%). The mean duration was 8.9 months. 3. The mean cumulative time of BI to 0 was 68.4 months Conclusion: These results suggest that after MDT, in most of MB, BI decreased within one year and it took 68.4 months for BI to be 0. At first, BI decreased relatively fast, however a longer period was required to become a state of BI 0.
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20MHz-고주파 초음파를 이용한 노년층과 청년층의 피부두께에 관한 비교 연구
이지호,김종일,최성우,이해광,김형옥 대한피부과학회 1999 대한피부과학회지 Vol.37 No.6
Background: Skin thickness for parameter of skin aging has been analysed with various methods. Skin thickness variations between the young and the old has been studied with various methods such as biopsies, calipers, micrometers, computer tomography, ultrsonography. But none of these methods evaluates skin thickness exactly. Objective: For the evaluation of age-dependent skin thickness changes, we compared the skin thickness of an old-aged group and a young group with 20MHz-ultrasonography. Methods: In order to identify the skin thickness variation between different age groups, 60 subjects, 30 aged 23-33, and 30 over 60, were studied with 20MHz-high frequency ultrasonogrphy (Dermascan C^輹, Cortex Technology, Hadsund, Denmark) on fourteen skin sites. This machine was designed to measure the thickness from the top of the epidermis to the bottom of the dermis. After storage of cross-sectional skin imaging, skin thickness was calculated with a computer assisted image-analysis program. Skin thickness of the old was analysed by age, sex, height and weight. Results: 1. In the old-aged group, skin thickness decreased in comparison with the young-age group. In men, the decrease of skin thickness in the old-aged group was significant on the chest, lower back, lower leg flexor, lower leg extensor, foot dorsum in comparison to the young-aged group(p�0.05). In women, the decrease of skin thickness in the old-aged group was significant on the cheek, chest, upper back and lower back in comparison to the young-aged group(p�0.05). 2. In men, skin thickness was thicker in comparison to that of females. 3. Skin thickness was well correlated inversely to age, but not correlated to weight and height. 4. Compared to other methods such as biopsy, computer tomography, conventional ultrasonography, the value of skin thickness with 20MHz-high frequency ultrasonogrphy was more reliable. Conclusion: By 20MHz-high frequency ultrasonogrphy, skin thickness decreased in the old-aged group in comparison to the young-aged group.
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