흰 쥐에서 비타민 A 흡수에 미치는 비타민 C 의 영향

김현옥,김제현,송정식 ( Hyun Ock Kim,Je Hyun Kim,Chung Suk Song ) 생화학분자생물학회 1974 BMB Reports Vol.7 No.2

The effect of vitamin C on the intestinal absorption of vitamin A was observed in the rat. The various protein content diets (rice, 10% casein added in rice, 10%, and 30% casein) were fed. Vitamin A (2,000-40, 000 IU) and vitamin C (10 ㎎) at each day were administered for 3-7 days by the tube-feeding and the intraperitoneal injection, respectively. Vitamin A content in serum and liver was determined by the method of Oser et al. (1943). The following results were obtained: 1) Vitamin A content in the serum was increased by vitamin C in the all in vivo experiments, and 30% casein diet enhanced vitamin C effect on the increasing content as compared with 10% casein diet. 2) Vitamin A content in the liver was increased by the vitamin C in 10% and 30% casein diets. 3) Vitamin C did not significantly change the net vitamin A content in serum and liver in the isolated perfused system. These results may indicate that vitamin C may give effect on the enhancement of the intestinal absorption of vitamin A, but not on the circulatory transport into the liver.

일 지역 성인의 고혈압 유병률 및 관리 실태

김현옥,Kim, Hyeon-Ok 한국지역사회간호학회 1999 지역사회간호학회지 Vol.10 No.1

In order to analyse the prevalence rate of hypertension and the actual conditions of control, we selected five districts out of eleven eups and myuns in Chinan Country. We administered structured questionaries to 309 adults above the age of 40, computerized the data using SPSS - PC+. More than 40.1% of adults over 40 in Chinan County have health disorders ranging from high blood pressure to hypertension including alert high blood pressure at 36.2%, relatively high. Among general characteristics, differences in the rate of hypertension were influenced by age, occupation and places of residence. Over 71 who are engaged in agriculture, who don't have jobs, who reside in Sungsu, Jungchun, Chinan-eup all have higher hypertension rates than other groups. Accordingly, the control of hypertension should be focused on these people. As a result of the control of blood pressure, the survey showed 93.0% of the subjects were checked mainly at hospitals clinics, health centers subhealth centers and community health posts more than once a year, relatively high level of blood pressure management. However, the difference between their blood pressure measurements at ordinary times and the level of blood pressure at the time of research was quite considerable. Only 47.3% of the subjects diagnosed with high blood pressure and 70.3% of the subjects with normal blood pressure recognized their blood pressure accurately 52.7% of the subjects diagnosed with high blood pressure showed errors in understanding their blood pressure at normal times. Because these errors can cause problems in the control of blood pressure, proper management should be executed through a systematic examination. As a result of the high blood pressure control condition, the average period of hypertension was 74.5( ${\pm}92.8$) months, 92.3% of the subjects were diagnosed with high blood pressure at hospitals clinics, health centers subhealth centers community health posts, but only 29.5% were examined after a general check up on high blood pressure was completed. 70.5% were diagnosed with high blood pressure only after measuring their blood pressure. 14.1% of the subjects were hospitalized because of falls influenced by high blood pressure. 33.3% attended hospitals and health centers regularily for medical treatment and this shows how low the rate of the control of blood pressure. Most people did not undergo medical treatment, because they had no painful symptoms (46.7%), they didn't need to take the medicine(28.9%), or they forget to take the medicine(20.0%). These problems in the control of hypertension were discovered in the process of diagnosing high blood pressure at health medical institutions. Many people did not recognize the need for consistent control of blood pressure. That is, although the diagnosis for high blood pressures performed at hospitals clinics, health centers subhealth centers and community health posts, was 92.3%, more than 70.5% of the subjects were not examined completely with regard to blood pressure. Accordingly, heath medical institutions must diagnose high blood pressure not only by only measuring blood pressure but also by using systematic process of examination. As for the people diagnosed with high blood pressure, one should perform consistent medical approaches and help them to recognize the importance of the continuous control of blood pressure through subject-oriented education. Problems the subjects experienced were the following numbness in the limbs easily paralyzed stitches in their shoulders which felt painful, stiff necks, occiputs felt heavy, headaches when they got up in the morning, felt dizzy when standing and moving their heads and poor eyesight. The rate of knowledge related to high blood pressure was 78.7 points, comparatively low. Whether they had normal blood pressure or hypertension made no difference. These results are not desirable. Adult-oriented education forgot the prevention and management of high blood pressu

진동긴박이 비타민 결핍 백서의 전위부 궤양발생에 미치는 영향

김현옥,전유상,김이식,송정석 ( Hyun Ock Kim,Yoo Sang Chun,Ei Sik Kim,Chung Suk Song ) 생화학분자생물학회 1969 BMB Reports Vol.2 No.2

Since the production of hyperplastic ulcers of forestomachs of rats fed on low protein diet by Fibiger in 1913, many investigators produced the same lesions on the rats. In this laboratory, the hyperplastic ulcers of forestomachs of rats fed on low protein diet was produced in a shorter period by shaking the rats. In this experiment, production of ulcers of forestomachs of the riboflavin or thiamine deficient rats by giving shaking stress was investigated. The results were follows; No ulceration of forstomachs of the riboflavin or thiamine deficient rats fed on 20% casein diet was produced by shaking the rats. However, severe hyperplastic ulcers of forestomachs of the thiamine deficient rats fed on 91% rice diet were produced by shaking the rats, while no change of those of rats fed 91% rice diet were observed by the same treatment. So it is concluded that the thiamine deficiency accelerates the production of hyperplastic ulcers of the forestomachs of rats fed on low protein diet.

현장탐방 고객감동 현장 - 에스엠비티(주) 전남지점

김현옥,Kim, Hyeon-Ok 한국작물보호협회 2008 자연과 농업 Vol.29 No.10

전통문화와 첨단산업이 공존하는 자족형 혁신도시를 추구하는 나주시. 영산강 문화의 뿌리를 둔 생명의 당이다. 배 주산단지인 이곳 나주에 '천우지베레린'을 확인시킨 에스엠비티(주) 전남지점(지점장 김현옥 44)이 자리하고 있다. 2006년 최초 1호 지점으로 설립, 에스엠비티(주)와 인연을 시작한 김지점장은 "고객과의 만남을 위해 현장으로 떠나는 매일 아침이 적지 않게 설레인다"면서 "하루 이동거리가 보통 250여km를 상회, 때론 지치기도 하지만 항상 생명이 살아 숨쉬는 현장의 목소리에 귀 기울이며 함께 꿈을 이룰 수 있어 행복하다'며 그의 환한 웃음 속에 열정을 내비친다. 이 같은 열정은 지난해 전국 우수지점에 선정된 영예와 무관치 않다. "영업력은 성실, 정보력, 대인관계, 적시적소의 운영 등 개인의 능력에 좌우된다"며 선두지점의 자부심을 드러내는 김 지점장은 "농가들은 작물보호제품의 인지도를 쉽게 바꾸려 하지 않아 우선 고객의 마음에 신뢰와 믿음을 심어주어야 한다. 끊임없는 제품연구와 정확한 정보 전달, 수요와 판매예측의 시장분석을 통해 적시적소에 적합한 제품을 공급해야 한다"면서 타사와의 차별화 전략에 대해 역설하며 그의 일상이 빼곡히 적혀있는 다이어리를 넘기며 또 다른 미래를 준비하고 있다.

외측 족근중족관절에 발생한 류마토이드 관절염의 건 개재 관절성형술을 이용한 치료 (증례 보고)

김현옥,박진성,이동영,남대철,Kim, Hyun-Ok,Park, Jin-Sung,Lee, Dong-Yeong,Nam, Dae-Cheol 대한족부족관절학회 2013 대한족부족관절학회지 Vol.17 No.4

Controversies exist regarding the treatment options for the end-stage arthritic change in the lateral tarsometatarsal joints. Arthrodesis has been frequently performed, but has a disadvantage of sacrificing a mobile joint. Resection arthroplasty also gained its popularity, especially in the patients with Rheumatoid arthritis, but possible hypermobility can lead to deformity. We report a successful clinical outcome of a patient with Rheumatoid arthritis in the 4th, 5th tarsometatarsal joints treated with tendon interpositional arthroplasties.

진동긴박(振動緊迫)이 비타민결핍(缺乏) 자서(自鼠)의 전위부(前胃部) 궤양발생(潰瘍發生)에 미치는 영향(影響)

김현옥,전유상,김이식,송정석,Kim, Hyun-Ock,Chun, Yoo-Sang,Kim, Ei-Sik,Song, Chung-Suk 생화학분자생물학회 1969 한국생화학회지 Vol.2 No.2

Fibiger 가 1913 년(年)에 저단백식이(低蛋白食餌)로 기른 백서(白鼠)의 전위부(前胃部)에 비후성(肥厚性) 궤양(潰瘍) 발생(發生)을 관찰(觀察)한 이래(以來) 많은 학자(學者)들에 의하여 같은 궤양(潰瘍)을 발생(發生)시키었다. 본교실(本敎室)에서는 저단백식이(低蛋白食餌)로 기른 백서(白鼠)에게 진동긴박(振動緊迫)을 가(加)하면 단시일(短時日)안에 전위부(前胃部)에 비후성궤양(肥厚性潰瘍)이 발생(發生)되는 것을 관찰(觀察)하였다. 본실험(本實驗)은 riboflavin 혹은 thiamine 결핍(缺乏) 백서(白鼠)에게 진동긴박(振動緊迫)을 가(加)하고 그 전위부(前胃部) 궤양(潰瘍) 발생(發生) 여하(如何)를 관찰(觀察)한 것이다. Since the production of hyperplastic ulcers of forestomachs of rats fed on low protein diet by Fibiger in 1913, many investigators produced the same lesions on the rats. In this laboratory, the hyperplastic ulcers of forestomachs of rats fed on low protein diet was produced in a shorter period by shaking the rats. In this experiment, production of ulcers of forestomachs of the riboflavin or thiamine deficient rats by giving shaking stress was investigated. The results were follows; No ulceration of forstomachs of the riboflavin or thiamine deficient rats fed on 20% casein diet was produced by shaking the rats. However, severe hyperplastic ulcers of forestomachs of the thiamine deficient rats fed on 91% rice diet were produced by shaking the rats, while no change of those of rats fed 91 % rice diet were observed by the same treatment. So it is concluded that the thiamine deficiency accelerates the production of hyperplastic ulcers of the forestomachs of rats fed on low protein diet.

초등학교 주변을 중심으로 본 서울시 도시녹지 현황 분석 및 고찰 - 원격탐사 방법을 이용한 식생분류 -

김현옥,Kim, Hyun-Ok 한국조경학회 2012 韓國造景學會誌 Vol.40 No.5

도시자연은 물리적 환경개선 기능은 물론 사회적, 정서적 측면에서도 중요한 역할을 한다. 특히, 학교에서 생활하는 시간이 많은 우리나라의 경우 학교 옥외공간을 비롯하여 인근에 조성된 녹지공간은 자연체험의 기회가 적은 도시 아이들이 가장 쉽게 자연을 접할 수 있는 일차적인 장소이다. 본 연구에서는 우리나라 대도시의 녹지현황을 학교 주변을 중심으로 살펴보고자 한다. 서울시 185개 초등학교를 선정하고, 학교 옥외공간을 포함한 반경 300m 이내(본 연구에서 '학교존'으로 정의) 주변 녹지 현황을 RapidEye 다중분광 인공위성 영상을 사용하여 분석하였다. 학교존 평균 녹지율은 약 21%이고, 최고 74%에서 최소 0.7%까지 편차가 매우 큰 것으로 나타났다. 그리고 과반수 이상의 학교존 녹지율이 20% 미만이다. 학교존 녹지율이 높은 학교 대부분이 산기슭에 위치하고 있어 산림면적이 학교존 녹지율을 높이는데 기여한 것으로 분석되며, 산림녹지의 경우 식생활력 또한 기타 도심지에 조성된 조경수목식재지보다 상대적으로 높은 것으로 나타났다. 반면, 학교존 녹지율이 낮은 학교들 대부분은 고밀 주택지 인근에 위치하고 있으며, 녹지의 식생활력 또한 상대적으로 낮게 나타났다. 도시산림을 제외한 시가화지역에서 학교존 녹지의 많은 부분을 차지하는 것은 아파트단지내 조경녹지시설이며, 그 밖에 친환경적인 학교 옥외공간이나 가로공원 등 도시오픈스페이스가 차지하는 비중은 미미하다. 이러한 현실을 감안하여, 도시계획적인 맥락에서 학교존 녹지율이 낮은 지역을 우선 대상으로 학교숲 조성사업을 지원하거나 주변지역의 옥상녹화를 장려하고, 학교주변 아파트단지내 녹지공간을 학교옥외공간과 유기적으로 연계하여 쉽게 접근할 수 있는 도시오픈스페이스로 개방하는 등의 체계적인 대책 마련이 필요하다고 하겠다. Urban nature plays an important role not only in the improvement of the physical environment but also from the perspective of psychological and social function. In particular, schoolyards as well as the green spaces near school surroundings function as a primary space for urban children to experience nature in Korea, as they spend most of their time at school. In this study, the status of urban green spaces near school surroundings was examined. For the analysis, 185 elementary schools in Seoul were selected and the green spaces within a radius of 300m(defined as 'school zone' in this study) were analyzed using the Rapid Eye multispectral satellite image data. The mean green space ratio of school zone accounts to about 21% with a high variation from 74% to 0.7% and more than half of the school zone have a green space ratio of less than 20%. Schools with a high green space ratio in their school zone are mostly located near urban forests, so forest areas particularly contribute to increase the green space ratio. Furthermore, forest vegetation shows relatively higher vitality than other green spaces located in urbanized areas. In contrast, schools with a low green space ratio in their school zone are mostly situated in high-density residential areas and the green spaces show relatively low vegetation vitality. Except for the urban forest, the majority of urban green spaces in urbanized areas are landscape green facilities in apartment districts. The other types of urban open spaces such as environmentally shaped schoolyards or street parks account only for a very small proportion of school surroundings. Therefore, it is needed to establish countermeasures in the context of urban planning; e.g. to promote the school forest projects preferentially by selecting schools with a extremely low green space ratio in their school zone, to foster roof greening in near surroundings, and to connect schoolyards organically with nearby apartment landscape green facilities as an easily accessible urban open space.

백서 가토 및 닭에 있어서 그 년령에 따라 조직내 Dehydroascorbic Acid Reductase 활성에 대한 연구

김현옥,사혜순,송정석,Kim, Hyun-Ock,Sa, Hae-Soon,Song, Chung-Suk 생화학분자생물학회 1973 한국생화학회지 Vol.6 No.3

백서 가토 및 닭의 여러장기에서 dehydro-L-ascorbic acid reductase(DHA-reductase)의 활성을 측정하고 다음과 같은 결과를 얻었다. 1) 백서 가토 및 닭의 각 동물의 간, 뇌, 신, 소장, 근육, 부신에서 DHA-reductase 활성은 모두 부신에서 높았고, 근육에서 가장 낮았다. 간, 뇌, 소장에서 DHA-reductase 활성은 부신에서 보다는 낮고, 근육에서 보다는 높았다. 그리고 신장에서는 간, 뇌, 소장에서 보다 약간 낮았다. 2) 간에서 DHA-reductase 활성은 백서와 가토에서는 생후 일차 떨어지다가 다시 증가 하였고, 닭에서 생후 처음부터 증가 하였다. 3) 백서에서 DHA-reductase 활성은 cytosol에만 있었다. Dehydro-L-ascorbic acid reductase (DHA-reductase) activities in various tissues of rats, rabbits and chicken were determined and the following results were obtained: 1) Among the DHA-reductase activities in liver, brain, kidney, small intestine, muscle and adrenal of rats, rabbits and chicken, the highest activity was found in adrenal and the lowest activity in muscle of each animal. The DHA-reductase activities in liver, brain and small intestine were lower than that in adrenal, but were higher than that in muscle of each animal and the activity in kidney was slighly lower than those in liver, brain and small intestine. 2) DHA-reductase activities were decreasing immediately after the birth but soon were increasing in liver of rats and rabbits, but the DHA-reductase activity in liver of chicken was increasing immediately after the birth. 3) DHA-reductase activity in rats was found only in cytosol.

흰 쥐에서 비타민 A 흡수에 미치는 비타민 C의 영향

김현옥,김제현,송정석,Kim, Hyun-Ock,Kim, Je-Hyun,Song, Chung-Suk 생화학분자생물학회 1974 한국생화학회지 Vol.7 No.2

백서에 있어서 비타민 C가 비타민 A의 장내 흡수에 미치는 영향에 관하여 관찰하였다. 백서는 백미식, 10% casein 첨가식, 10% casein 식, 30% casein 식 등 단백함량이 다른 여러 식이로 사육하였다. 비타민 A는 실험에 따라 2000 혹은 40,000 I.U.를 매일 tube-feeding 방법으로, 비타민 C는 10mg 씩 매일 복강내 주사로 3~7일간 투여하였다. 바다민 A의 혈액과 간내의 농도는 삼염화안티몬에 의한 색반응을 이용하여 측정하였으며 다음과 같은 결과를 얻었다. 1) 모든 생체내 실험에서 혈청 비타민 A의 농도는 비타민 C에 의하여 증가되었고 특히 30% casein 식이군은 10% casein 식이군에 비하여 비타민 C의 영향이 컸다. 2) 10%, 30% casein 식이군에서 간내 바타민 A 농도는 비타민 C에 의하여 증가되었다. 3) 유리관류 간 실험에서 비타민 C는 혈청과 간의 비타민 A 농도 변화에 아무 영향도 주지 못하였다. 이러한 결과로 보아 바타민 C는 비타민 A의 장내흡수에는 관여하지만 혈청에서 간으로의 이동에는 관여하지 않는 것 같다. The effect of vitamin C on the intestinal absorption of vitamin A was observed in the rat. The various protein content diets (rice. 10% casein added in rice. 10%, and 30% casein) were fed. Vitamin A(2,000-40,0000 IU) and vitamin C(10 mg) at each day were administered for 3-7 days by the tube-feeding and the intraperitoneal injection, respectively. Vitamin A content in serum and liver was determined by the method of Oser et al. (1943). The following results were obtained: 1) Vitamin A content in the serum was increased by vitamin C in the all in vivo experiments, and 30% casein diet enhanced vitamin C effect on the increasing content as compared with 10% casein diet. 2) Vitamin A content in the liver was increased by the vitamin C in 10% and 30% casein diets. 3) Vitamin C did not significantly change the net vitamin A content in serum and liver in the isolated perfused system. These results may indicate that vitamin C may give effect on the enhancement of the intestinal absorption of vitamin A. but not on the circulatory transport into the liver.

백서 가토 및 닭에 있어서 그 연령에 따라 조직내 Dehydroascorbic Acid Reductase 활성에 대한 연구

김현옥,사혜순,송정식 ( Hyun Ock Kim,Hae Soon Sa,Chung Suk Song ) 생화학분자생물학회 1973 BMB Reports Vol.6 No.3

Dehydro-L-ascorbic acid reductase (DHA-reductase) activities in various tissues of rats, rabbits and chicken were determined and the following results were obtained: 1) Among the DHA-reductase activities in liver, brain, kidney, small intestine, muscle and adrenal of rats, rabbits and chicken, the highest activity was found in adrenal and the lowest activity in muscle of each animal. The DHA-reductase activities in liver, brain and small intestine were lower than that in adrenal, but were higher than that in muscle of each animal and the activity in kidney was slightly lower than those in liver, brain and small intestine. 2) DHA-reductase activities were decreasing immediately after the birth but soon were increasing in liver of rats and rabbits, but the DHA-reductase activity in liver of chicken was increasing immediately after the birth. 3) DHA-reductase activity in rats was found only in cytosol.