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RISS 인기검색어
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- 저자 : 김석완 ( Seoung Wan Kim ) (검색결과 1 건)
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원저(原著) : 한국인 헌혈자에서의 C형간염항체 양성률 고찰 -제3세대 효소면역측정법 및 확인시험-
최범열 ( Bum Ryoul Choi ),최중문 ( Joong Moon Choi ),김혜경 ( Hye Kyoung Kim ),김석완 ( Seoung Wan Kim ),민태희 ( Tai Hee Min ) 대한임상병리사협회 1995 임상수혈검사학회 발표자료집 Vol.2 No.1
After test the blood samples donated by 33,838 Koreans with Lucky HCD, 3rd generation Hepatitis C diagnostic reagent, using ELISA method, We selected the samples found positive and retest them with Lucky HCD confirm, which is the diagnostic reagent confirming Hepatitis C in Immunoblot method and achieved the following results. 1. Among blood doner 33,838, 133 which is equivalent to 0.39 % of the total were found anti-CV positive. Among the male, 31,023(92 %), 126 which is equivalent to 0.41 % were found positive. Among the female 2.815(8 %), 7 which is equivalent to 0.25 % were found positive. 2. When tested 133 which were found positive by ELISA method with Lucky HCD confirm in order to confirm the test results, 40(30 %) were found positive, 93(70 %) were false positive, 17(3 %) were indeterminate, and 76(57 %) were negative. Summarizing from the total blood donors, 0.12 % were anti-HCV and the false positive percentage except indeterminate were 0.22 %. 3. The ALT value of 32,159(95 %) of the total blood donors were less then 45IU/L(normal). When 32,159 were tested with HCD3.0, 109(0.34 %) were found anti-HCV. When 109 were rested with Lucky confirm, 24(0.07 %) were found positive. 771(2.3 %) of the total blood donors were having ALT value from 46 to 59 IU/L. When 771 were tested with HCD3.0, 8 were found positive. When 8 were retested with Lucky confirm, 3(0.39 %) were found positive. 908(2.7 %) of the total donors were having ALT value above 60IU/L. When 908 were tested with HCD 3.0, 16(1.76 %) were found positive. 16 were retested with Lucky confirm, and 13(1.43 %) were found positive. These statistics show that the potential percentage of HCV positive grows in the proportion of the ALT value. As shown above, the substantial quantity of the blood donated are presently decided false positive by the Hepatitis C Antibody test using 3rd generation ELISA method in the Red Cross Blood Center and destroyed. By noticing such results to the blood donors having goodwill, The Red Cross might lose it`s faith for testing the blood and it will eventually affect the controlling the blood donors To supplement the current testing system, we consider that we need to have final confirm test at the end of the test procedure before release the test results.
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