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국내 추출물 분야 연구의 주름 관리 효과에 대한 메타분석
김남산(Nam-San Kim) 한국인체미용예술학회 2021 한국인체미용예술학회지 Vol.22 No.2
Meta-analysis was conducted to comprehensively analyze the number of prior studies that reported extract efficacy in terms of improving wrinkles in the cosmetics sector. The data was collected and verified using the search term antioxidant and wrinkle improvement for studies published from 2000 to February 2021 for research purposes, and a total of 18 papers were used for analysis. The data analysis was conducted using Excel and the CMA2 program, and a 95% confidence interval was calculated by selecting Random Model, interpreting in terms of small effect size less than 0.3 , medium effect size less than 0.3“-0.8 , and large effect size, >0.8 . As a result, first, the overall effect size for the extract related to wrinkle improvement is 0.545 (Z=3.110, p<0.05), which is a moderate effect, The second extractd showed significant effect sizes, and included Rutin (1.573), Ogafi (1,372), Gold Silver Flower (1.329), Rose Haute (1.133), Bulgaria (1.022). Third, the effect size of an extract on wrinkle improvement is (0.827), which is a large effect and percutaneous moisture (0.616) was shown to have a medium effect size. The lower strain effect was (1.133). There was a large effect sizes less less than 4 weeks (0.717) and less than 2 weeks (0.686). Therefore, it was found that the application of extracts to evaluate the effectiveness of wrinkle improvement was appropriate, and the extracts were effective for moisturizing the skin, wrinkles, and percutaneous moisture.
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글릭콜릭산 필링 후 rhEGF and Palmitoyl pentapeotide-4의 피부 재생 효과
주지현 ( Ji Hyun Ju ),김도현 ( Do Hyeon Kim ),박건 ( Kun Park ),김남산 ( Nam San Kim ),김정희 ( Jeonghee Kim ) 한국미용학회 2020 한국미용학회지 Vol.26 No.1
Glycolic acid peel is a popular superficial peeling technique associated with low morbidity and prompt recovery. These processes, as well as the final step of corneodesmolysis, which mediates exfoliation, are often disturbed by environmental conditions, resulting in dry, flaky skin conditions. Therefore, aftercare is required to avoid these side effects and achieve the maximum possible improvement in skin condition. To evaluate the skin regeneration effect of rhEGF and palmitoyl pentapeptide-4 after glycolic acid peeling. A base gel, a gel containing rhEGF, and a gel containing palmitoyl pentapeptide-4 were prepared, and their safety was evaluated by patch test. The 30 healthy female volunteers (age 25-39 years) underwent a glycolic acid (20%) face peel once per week and then the prepared gels were applied to the face for 4 weeks. Stratum corneum hydration, transepidermal water loss (TEWL), and erythema index were then evaluated. No specific skin reaction in prepared gels was detected by a patch test. In the application group of rhEGF and palmitoyl pentapeptide-4, stratum corneum hydration is increased, TEWL and erythema index are reduced. Therefore, the skin regeneration effect was confirmed. The skin regeneration effect of the palmitoyl pentapeptide-4 application group was shown to be the best result in particular. The gels containing rhEGF and palmitoyl pentapeptide-4 were safe and effective for skin recovery after glycolic acid peeling. The palmitoyl pentapeptide-4-containing gel was superior to the rhEGF-containing gel in terms of skin regeneration after peeling.
KCI
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