Synthesis and properties of waterborne polyurethane-acrylate hybrid/graphene nanocomposite

강무석,김병규 한국고분자학회 2014 한국고분자학회 학술대회 연구논문 초록집 Vol.2014 No.10

Emulsion Polymerization of Acrylic Rubbers

강무석,김병규 한국고분자학회 2013 한국고분자학회 학술대회 연구논문 초록집 Vol.2013 No.10

혈류부전을 동반한 하지의 다양한 미세수술적 구제술

우상현,김성언,설정현,강무석 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.5

In the past 5 years, the authors have performed microsurgical reconstruction of the lower leg in 37 patients. Among them, modified microsurgical salvage procedures were performed in 11(29.7) cases with vascular compromise, suggested by the preoperative angiogram of the affected lower leg demonstrating no visible, or only one visible major arter. Modified salvage procedures included free flap operations using distally-based arterial inflow(n=2), temporary diversion of the single main artery with secondary vein grafting(n=2), cross-leg fashioned free flaps(n=4), and end-to-side anastomosis of the main artery((n=1). In absence of arterial flow after lower leg trauma, as interpositional vein graft(n=2) was performed to restore blood flow. No vascular problems occurred after the free flap transfer. However, 9 patients experienced different degrees of limping gait, ranging from as mild(n=2), moderate(n=6) to severe(n=1) at the mean follow-up period of 18 months. In reconstruction of a vascular compromised lower leg, modified salvage procedures should be reviewed and selected after exploration of all vessels, both proximal and distal to the zone of the injury. When evaluating what method is the most appropriate, socioeconomic efficiency and patients' individual requirments should be considered.

가토의 하악골 연장시 Sodium fluoride 투여가 골형성에 미치는 영향

김용하,설정현,변우목,김정철,우상현,강무석 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.4

The purpose of this study was to improve bone formation and shorten the period involved in distraction osteogenesis using sodium fluoride (NaF). This has been used in managing osteoporosis for several decades. This study was carried out on 40 New Zealand white rabbits. Twenty animals were used for a control group (no medication) and 20 for the experimental group. NaF 1 mg/kg/day was administered to each experimental animal via drinking water beginning 4 weeks prior to surgery and continued until sacrifice for examination. A distraction device was applied to the left mandible along a plane perpendicular to the direction of osteotomy. After a 5-day latent period, the mandibles were lengthened at 1 mm per 24 hours for 10 days. Five rabbits from each group were sacrificed on the 1st day, 2nd week, 4th week and 8th week of the consolidation period. After lengthening, all the rabbits developed a severe cross-bite. By the 4th week, cortical continuity was seen. Bone densities at the site of bony lengthening were measured by quantitative computer tomography (QCT) and dual X-ray absorptiometry (DXA). The results were as follows: the measurements of the experimental group were significantly higher than of the control group by the 1st day of the consolidation period (p<0.05) and insignificantly higher after the 2nd week. Histologically, in the experimental group, there were more osteoblasts, increased and thickened trabeculae and more mature lamellar bones than in the control group. This study showed that osteogenesis of the experimental group was significantly higher during and immediately after distraction. Our study suggested that the use of NaF could improve bone formation and decrease the period of distraction osteogenesis if a safe dose and method of fluoride administration can be determined for growing humans.

가토의 하악골 연장에서 잠복기간 단축의 영향

김용하,설정현,최준혁,강무석 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.5

To evaluate the effect of shortening the latent period for distraction osteogenesis, the authors experimented with distraction osteogenesis for a 24-hour latent period in the mandibles of rabbits. This study was carried out on 32 New Zealand white rabbits, each weighting 2000 to 2500 gm. Twenty animals were used for the control group and 12 for the experimental group. A unilateral external fixation device was applied to the left mandible. The mandibles were lengthened at 1 mm per 24 hours for 10 days. Five rabbits from the control group and three from the experimental group by random selection were sacrificed on the first day, and at the second, fourth and eighth week of the consolidation period. After lengthening bone densities at the site of the left mandibular bony lengthening were measured by quantitative computer tomography (QCT) and dual energy x-ray absorptiometry (DXA). As a result, the DXA value showed no difference compared to the control group after two week's consolidation. The trabeculae were thicker and had begun to be surrounded by lamellar bone both in the control and experimental groups histologically. In conclusion, the results of this study indicate that the osteogenetic effect in the experimental group was nearly the same as in the control group. If stable fixation and minimal periosteal dissection were performed during the procedure, the latent period would not be an important factor in distraction osteogenesis of membranous bone.

디지털 치료제에 적합한 전자동의 프로세스 개발: 디지털 도구의 차이가 사용자에게 미치는 영향

강무석(Museok Kang),한지현(Jeehyun Han),오진환(Oh jinhwan),조윤영(Yunyoung Jo),김진우(Jinwoo Kim) 한국HCI학회 2022 한국HCI학회 학술대회 Vol.2022 No.2

디지털 기술의 발전으로 인해 디지털 치료제 산업이 전 세계적으로 증가하고 있다. 디지털 치료제는 사용자 맞춤형 의료 서비스를 제공할 수 있으며, 독성과 부작용이 적고 비용 대비 효과적이기 때문에 새로운 치료 대안으로 떠오르고 있다. 디지털 치료제 역시 사람을 대상으로 제공하는 서비스기 때문에 전통적인 의학적 검증과 신뢰할 수 있는 연구 디자인을 통해 검증을 받아야 한다. 그러나 대부분의 디지털 치료제 및 디지털 헬스케어 서비스들을 이해하고 연구 참여에 도움이 되는 사전동의 형태는 과거 프로세스와 동일하며, 그로 인해 사용자들의 연구 참여 및 이해 수준이 떨어져 연구 참여를 하지 않을 수 있다. 본 연구는 기존 사전동의 방법에 대한 이해를 바탕으로 디지털 치료제에 적합한 전자동의 프로세스를 제안한다. 이를 위해 세 가지 형태의 디지털 도구를 제공하여 사용자의 연구 이해 수준, 연구 참여 의도, 정보 제공 의도를 확인함으로써 디지털 치료제에 적합한 전자동의 프로세스를 개발하는데 큰 목적을 둔다.

화상후 만성궤양에서 발생한 평활근육종의 치험례

강무석,우상현,설정현,최준혁 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.2

Leiomyosarcoma is a malignant tumor showing smooth muscle differentiation, and it accounts for 2% to 8% of soft tissue sarcoma. Clinically, substantial mortality and morbidity are related to the propensity for distant metastasis and local recurrence, respectively. Microscopic findings characteristically reveal intersecting bundles of spindle-shaped cells having fibrillar cytoplasm and blunt-ended nuclei. Immunohistochemistry for intermediate filaments is helpful in establishing a definitive diagnosis. We experienced a case of large protruding leiomyosarcoma that developed on an old burn scar of the medial calf of a 45-year-old man. On preoperative evaluation, we recommended amputation due to a distant metastasis to the lung(stage Ⅳ). As the patient refused amputation of his lower leg, the tumor was radically excised and immediate reconstruction was done using free latissimus dorsi muscle flap and skin graft. Four months after excision despite adjuvant chemotherapy, amputation was performed due to local recurrence.

제한적 접근을 통한 관골 부정유합의 재건

설정현,강무석,김용하 大韓成形外科學會 1988 Archives of Plastic Surgery Vol.25 No.6

This study includes 40 patients of post-traumatic facial bone deformities to whom underwent realignment of zygomatic bone. In 13 cases, we modified the approach technique using limited exposure such as subciliary, intraoral and preauricular incisions instead of conventional wide exposure. Preoperative evaluation of deformity was done by using x-rays, photographs and detail communication with the patients. Through this limited exposure, osteotomy and repositioning of the zygoma were accomplished. There were no postoperative differences between wide and limited exposure, but limited exposure was more advantageous in terms of reduced operative time, transfusion, hospitalization and scaring. This approach was an effective method for the relatively simple tetrapod type-malunited fracture of zygoma without comminution.

835명 환자에서 1,210예의 안면골 골절에 대한 분석 : 최근 5년간 분석

김용하,강무석,정재호,최병철,설정현,우상현 大韓成形外科學會 1998 Archives of Plastic Surgery Vol.25 No.4

This retrospective study was undertaken to provide information when considering aspects of future prevention and quantifying demand fir medical services. And it comprised 835 patients with facial bone fractures in various accidents and treated in the department of Plastic and Reconstructive Surgery, the Yeungnam University Hospital during the past five years from January 1991 to December 1996. The medical records of this 835 patients(1,210 fractures) were reviewed and analyzed in order to obtain the clinical pattern and understand the therapeutic tendency. The following results were obtained; 1. The greatest number of patients were sustained facial bone injuries between midnight and 3:00. The monthly incidence showed in September at the most and at the least in December. The increase of facial bone injuries of 11.3% per year was shown. 2. The mean age of patients was 30 years. The most prevalent age group was at third decade(31.9%). Males were predominated more than female(3.6 : 1). 3. The most common cause was traffic accidents(41.6%) followed by violence, fall, industrial accidents and others. 4. The most common fracture was found in the nose(35.1%) followed by mandible(22.6%), zygoma(21.1%), and maxilla(11.2%). 5. Associated injuries were as following order of frequency; ophthalmologic injury(21.0%), other facial bone fractures(18.2%), head injury(10.2%). 6. Open reduction was used for 53.9% of total cases while 40.6% of total cases required closed reduction, and 5.5% of total cases treated conservatively. The complication rate was 18.5% and complications were as following order of frequency; facial asymmetry(37.2%), diplopia and enophthalmos(19.4%), and local infection(12.8%).

다양한 술식을 이용한 유두유륜의 재건

김해진,강무석,정재호,설정현 대한미용성형외과학회 1999 Archives of Aesthetic Plastic Surgery Vol.5 No.2