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      저자 : 金貞天(Chung Ock Kim) (검색결과 1 건)
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        Chlorhexidine Gluconate Solution 의 殺園效果에 關한 寶驗的 硏f究

        鄭文植(Moon Shik Zong),鄭圭寬(Kyu Kwan Chong),金泰植(Tae Shik Kim),金貞天(Chung Ock Kim) 한국환경보건학회 1987 한국환경보건학회지 Vol.13 No.1

        Owing to the modification of testing methods of disinfectants or antiseptics, variations of bacteria according to characteristics of regions and resistance changes of bacteria, it is necessary that the bactericìdal activities of disinfectants or antiscptics should be reevaluated nowadays. This study was carried out to reevaluate in the vitro bactericidal activity of Chlorhexidine gluco. nate solution. The results of experiment were summarized as follows. 1. For Chlorhexidine gluconate solution, minimal inhibitory concentrations of total bacteria taken from sewage water and Legionella bozemanii were 2.0 x 10-3%, 1.0 x 10-2%, respectively and were comparatively high. Minimal inhibitory concentration of Shige/la flexneri was 1.6 x 10-4%, and was comparatively low. 2. For total bacteria taken from sewage water, it was killed within 15 minute in 0 .1 % Chlorhexidine gluc‘)nate solution w hen number of cells was 1 .6 x 107 fm1. 3. For 0.0125% Ch10rhexidine gluconate solution, decimal reduction times of Ps. aeruginosa. S. typhi. E. Coli were 45 sec, 25 sec, 18 sec repectively. For 1%, 0.125% Chlorhexidine gluconate solution, deciml!l reduction times of Legionella bozemanii were 10 sec, 45 sec respectively. 4. There was significantdifference in the bactericidal activity of Chlorhexidine gluconate solution according to temperature. 5. Phenol coefficient of Chlorhexidine gluconate solution as using Staph. aureus was 100 and comparatively rugher than that of other disinfectants. 6. In comparison with other disinfectants‘ Legionella bozemanii was killed witrun 5 minutes in 0.02% KMn04 and 0 .1 25% CWorhexidine gluconate solution but was not ki1Ied within 3 minutes in 1% O-cresoI. 1 % PhenoI.

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