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개솔새(Cymbopogen tortilis) 精油가 胃液分泌 및 胃運動에 미치는 影響
朴駿瀅,鄭基坤 慶北大學校 1984 論文集 Vol.38 No.-
Cymbopogen tortilis is native weeds which is widely distributed in Korean fields and mountains and its flower contains a strong aromatic essential oil. It is known that the essential oil of Cymbopogen tortilis contains borneol, cadinene, camphene, and elemicin etc. But, there is no report about the effect of essential oil of Cymbopogen tortilis or its constituents on the gastric secretion and the gastric motility. To examine the effect of essential oil of Cymbopogen tortilis on the gastric secretion in rats and the gastric motility in pigeons, this paper was investigated. The results were as follows. The intraperitoneal administration of 1% essential oil solution of Cymbopogen tortilis at the ratio of 1.0ml, 0.5m1, 0.25ml/l00g B.W. to rat reduced their average gastric secretion volume to 2.1±0.29m1, 4.4±1.02m1, and 4.7±1.04ml respectively. In contrast to 9.5±1.3m1 of control rat's secretion. these numbers show 77.89%, 53.68% and 50.53% of gastric secretion inhibition rate. In pigeons, transient gastric inhibition which can be divided into 2 types was observed by the intraperitoneal injection of the drug at the same ratio to that of rats. In one type, gastric motility was inhibited in the state of transient gastric relaxation after drug administration, it recovered to normal with time. In the other type, gastric motility was inhibited transient gastric relaxation, soon its tone moved into contraction state, maintained this condition for some time, and this condition gradually recovered to normal. In conclusion, the essential oil of Cymbopogen tortilis inhibits strongly gastric secretion in rats and transiently gastric motility in pigeons.