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정맥피판의 생존에 지연조작술과 Fibronectin 및 Basic fibroblast Growth Factor의 효과
이정형,조병채,백봉수 大韓成形外科學會 1994 Archives of Plastic Surgery Vol.21 No.5
This study was conducted to evaluate the survival rate of three groups of venous flaps The first group is a proximal pedicled venous flap with one vein, and the second group is a delayed proximal pedicled venous flap with one vein and this second group was subdivided into 5,7,10, and 14days delayed groups. The third group consists of a fibronectin injection group and a basic fibroblast growth factor injection group to the group 1 and group 2. 10 venous flaps were elevated from the posterior surface of rabbit's ears for each group. The results were as followings : The survival rate of a proximal pedicled venous flap with one vein(the first group) was 38.5%. The survival rates of delayed proximal pedicled venous flap with one vein(the second group) were 51.4, 65.2,97.1 and 99.0% in 5,7,10 and 14 days delay. There was a significant increase in survival rate than the first group(p<0.001). In the fibronectin injection group, survival rates were 75.6% in the first group, and 72.1, 80.5,99,99.0% in 5,7,10,14 days delayed second group. The survival rates were significantly increased than those of the first and second group(p<0.001). In the basic firboblast growth factor injection group, the survival rates were 78.3% in the first group, and 79.7,83.2,99.05% in 5,7,10,14 days delayed second group. The survival rates were also significantly increased than those of the first and second group(p<0.001). These findings suggest that delay procedure, fibronectin and basic fibroblast growth factor increase the survival rate of a venous flap.