RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 원문제공처
        • 등재정보
        • 학술지명
        • 주제분류
        • 발행연도
        • 작성언어
        • 저자
          펼치기

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • KCI등재
      • KCI등재
      • KCI등재
      • 消化性潰瘍의 手術前後 胃酸度 및 胃 Pepsin値의 變動

        徐在皓 고려대학교 의과대학 1966 고려대 의대 잡지 Vol.3 No.1

        The problem of peptic ulcer therapy is not the relief of symptoms, but the prevention of recurrent ulceration and complications. The main objective of surgical treatment is to reduce the acid secretion of the gastric mucosa. Therefore, the observation of hydrochloric acid and pepsin in gastric juice before and after operations for the purpose of studying surgical treatment of peptic ulcer with different operative choice, is being studied on our department from both physiochemical and clinical standpoints including roentgenologic studies with 28 patients of peptic ulcer ranging from 18 to 66 of ages in both female and male. In this paper we give the results of 1) Billroth Ⅱ type subtotal gastrectomy, 2) antrectomy with vagotomy, and 3) Billroth Ⅱ type subtotal gastrectomy with vagotomy on gastric acid secretion and gastric pepsin. 1) Effect of Billroth Ⅱ subtotal gastrectomy on acid secretion and gastric pepsin is a considerable reduction. Preoperative mean is 57.36±21.81 in gastric acid and 1774.07±740.59 in gastric pepsin. Postoperative mean is 3.03±1.36 in gastric acid and 1557.29±654.31 in gastric pepsin. The mean reduction for the 8 subjects was 94.56 per cent in gastric acid secretion and 12.40 per cent in gastric pepsin. 2) The results for antrectomy with vagotomy was observed. Each mean of gastric acid and gastric pepsin is 52.28±9.73, 1571.86±306.45 in preoperative and 2.78±1.93, 1370.62±256.24 in postoperative. A substantial mean reduction in 5 patients was 95.2 per cent of acid secretion and 13.5 per cent of gastric pepsin. 3) Billroth Ⅱ type subtotal gastrectomy with vagotomy results in a very marked reduction of acid secretion in these patients. Preoperative mean is 50.95±16.05 in gastric acid and 1476.17±657.75 in gastric pepsin. Postoperative mean is 1.875±1.91 in gastric acid and 1242.16±524.30 in gastric pepsin. The mean reduction in 12 cases was 96.22 per cent of gastric acid secretion and 15.00 per cent of gastric pepsin. In these results, we submit the Billroth Ⅱ type subtotal gastrectomy with vagotomy reduces most effectively the level of the gastric acid secretion and gastric pepsin for the peptic ulcer surgery.

      • 膽囊空腸吻合術과 膽囊空腸吻合 및 空腸間吻合術의 實驗的硏究

        徐在皓,睦敦相 우석대학교 의과대학 1971 우석의대잡지 Vol.8 No.2

        Few systematic, comparative investigations have been performed on liver function, bile bacteriology and histopathological view during complete experimental biliary stasis together with a follow-up after release of the obstruction in dogs. Some biliary decompression techniques were performed for restoring bile flow to the jejunum 10 days after biliary obstruction. The following variables were studied before, during and after release of complete biliary obstruction: hemoglobin concentration in blood, bilirubin, protein, cholesterol, activities of alkaline phosphatase and transaminase. Bile culture, biliary reflux and histopathological findings of the liver were studied. 1) After 10 days' biliary stasis progressive anemia developed. After release of the biliary obstruction by decompression procedures, the hemoglobin concentration of the blood and body weight soon returned to normal. 2) The concentration of bilirubin especially direct reacting bilirubin reached a higher level after 10 days' biliary stasis. After release of the stasis, the bilirubin concentration returned to normal in both cholecystojejunostomy and cholecystojejunostomy with entero-enterostomy groups. 3) The observations were nade during biliary obstruction for the serum cholesterol, activity of alkaline phospatase and serum transaminase which increased markedly after 10 days's obstruction. The mean value of serum G.P.T. were more increased than G.P.T.. The G.P.T. activity was thus considered to be a better mirror of biliary stasis on the liver cells. After release of stasis, their activities returned to almost normal. 4) Serum globulin and thymol turbidity were increased during biliary obstruction, and returned to almost normal after release of the obstruction. 5) After complete biliary obstruction, the bile was sterile as in the control group while many organisms such as enterococcus were cultured after biliary-intestinal anastomosis in both biliary decompression groups. 6) The most anastomosed stomas between biliary and intestinal tract were shown to be stenosed slightly to moderately. Reflux into the biliary tract was present in all in face of the entero-enterostomy. 7) The most striking feature of the liver during the experimental biliary obstruction was cholestasis, which resulted in the dilatation of ductules, and the bile plugs in canaliculi, particularly in the centrilobular area. A significant degree of ductal cell proliferation and more prominent bile pigmented granules in Kupffer cells were observed. Focal necrosis of the liver cells of the centrilobular area were found especially in dogs which showed a marked increase of serum G.P.T.. Edema of the portal tracts, infiltration of inflammatory cells, proliferation of collagen fibers and periductal fibrosis were more remarkable in complete biliary obstruction group. After release of the obstruction by surgical decompression, slight bile pigmented granules in the Kupffer cells were found and moderate degree of infiltration of the inflammatory cells, except neutrophil, was seen with proliferation of collagen fibers and periductal fibrosis in both groups. 8) Gallbladder and the common bile duct showed marked infiltration of inflammatory cells in both cholecystojejunostomy and cholecystojejunostomy with entero-enterostomy groups. The reaction was rather severe in the gallblader. 9) There was no differencies between cholecystojejunostomy and cholecystojejunostomy with entero-enterostomy in liver function test, histopathology, degree of the stricture, biliary reflux and bacterilolgy.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼