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- 저자 : 崔乙順 (검색결과 3 건)
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加齡이 마우스 十二指腸 細胞更新系 에 미치는 影響에 關한 自記放射法的 硏究
崔乙順 고려대학교 의과대학 1972 고려대 의대 잡지 Vol.9 No.1
Postnatal growth and ageing effect on the cell renewal system of duodenal tissues were observed by means of microautoradiography. As experimental animals, 29 male and 38 female mice devided into different age groups; suckling young (4-day, 1 week, 2-week, and 3-week old), young adult (6-week old) and old adult (more than 50-week old) were observed. Single dose of H³-thymidine, 0.8 microcurie per gram of body weight were administered by intraperitoneal injection and labeling indices were counted through autoradiographs. 1. Cell renewal of the duodenal epithelium showed a generally high rate throughout the various ages. In the suckling young. the radioactive index rose progressively attaining a maximal value in the young adult groups. 2. In regards to the lamina propria, labelings were gradually decreased reaching minimal level in 3-week group. But in the young adult ages the renewing frequency showed a considerable rise. 3. The cell renewing behavior of the tunica muscularis externa differed from the above tissue components. rather it showed similar pattern of general muscular tissue. To elaborate, younger the age, higher the radioactive index. Finally, after 3 weeks almost no nuclear labeling was observed. 4. That the ovarian cycle has strong influence on the renewal of the epithelial cell was demonstrated during estrus of the young adult. A reverse phenomen was detected in the old adult, whether ageing effect and hormonal influence are involved factors in cell renewing still remains to be elucidated.
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申英澈,金聖淑,崔乙順 우석대학교 의과대학 1971 우석의대잡지 Vol.8 No.1
The author obtained the following results through the microscopic observation of fat storing cells in livers of 35 mice, 17 of them are normally fed mice containing 8 female, and 18 of them are fasted. 1. Concerning the number and morphological characteristics of fat storing cells of liver, no sexual difference were noted. 2. A large number of the fat storing cell contains single fat droplet measuring 2 to 3 microns in diameter. 3. The number of fat storing cell increased by fasting(short duration). The maximum number was observed at the 48 hrs. fasting group and gradual decrease was noted thereafter. 4. The rate of appearance of single fat droplet in the cell reduced when the cell number increased.
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