http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Development of Creatine and Arginine-6-Oligomer for the Ring-Opening Polymerization of Cyclic Esters
Ewa Oledzka,Marcin Sobczak,Mateusz Kolakowski,Bartlomiej Kraska,Wojciech Kamysz,Waclaw Kolodziejski 한국고분자학회 2013 Macromolecular Research Vol.21 No.2
Natural creatine and arginine-6-oligomer have been effectively engaged as ring-opening polymerization initiators of poly(L-lactide) (PLLA) and poly(ε-caprolactone) (PCL) in bulk. The nonlinear structure and thermal properties of the resulted polymers were further elucidated by 1H, 13C nuclear magnetic resonance, and a modulated differencial scanning calorimetry (MDSC). Thermal analysis indicated that the synthesized polymers had lower melting points, glass-transition temperatures, fusion enthalpy, and crystallization temperature than those of linear PCL or PLLA due to the presence of the arginine-6-oligomer in the macromolecule and crystalline imperfections caused by the branched structure. This study provides an efficient and metal-free method for the synthesis of branched biodegradable polymers with incorporated compounds, which exhibit therapeutic properties, adequate for the drug carrier applications.
( Baranska Rybak Wioletta ),( Malgorzata Dawgul ),( Sylwia Bielinska ),( Bartlomiej Kraska ),( Lidia Piechowicz ),( Wojciech Kamysz ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.5
Nowadays, there are a number of colorimetric techniques available for the determination of a time killing assay in a manner much easier and faster than those previously more commonly used, which were much more time-consuming and laborious colony counting procedures. Here, an attempt has been made to test the antimicrobial peptides of Citropin 1.1, Palm-KK-NH2, and Temporin A on a reference strain of Staphylococcus aureus using resazurin as the cell viability reagent. Staphylococcus aureus was exposed to the test compounds over varying periods of time and the metabolic activity measured, with a profile of antimicrobial activity then established. The results are in agreement with data from previous literature, thus confirming the relevance of the application of resazurin for the testing of antimicrobial agents.