http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : ( Weipeng Jing ) (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
An open Scheduling Framework for QoS resource management in the Internet of Things
( Weipeng Jing ),( Qiucheng Miao ),( Guangsheng Chen ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.9
Quality of Service (QoS) awareness is recognized as a key point for the success of Internet of Things (IOT).Realizing the full potential of the Internet of Things requires, a real-time task scheduling algorithm must be designed to meet the QoS need. In order to schedule tasks with diverse QoS requirements in cloud environment efficiently, we propose a task scheduling strategy based on dynamic priority and load balancing (DPLB) in this paper. The dynamic priority consisted of task value density and the urgency of the task execution, the priority is increased over time to insure that each task can be implemented in time. The scheduling decision variable is composed of time attractiveness considered earliest completion time (ECT) and load brightness considered load status information which by obtain from each virtual machine by topic-based publish/subscribe mechanism. Then sorting tasks by priority and first schedule the task with highest priority to the virtual machine in feasible VMs group which satisfy the QoS requirements of task with maximal. Finally, after this patch tasks are scheduled over, the task migration manager will start work to reduce the load balancing degree.The experimental results show that, compared with the Min-Min, Max-Min, WRR, GAs, and HBB-LB algorithm, the DPLB is more effective, it reduces the Makespan, balances the load of VMs, augments the success completed ratio of tasks before deadline and raises the profit of cloud service per second.
-
-
Gao Ran,Guo Wenjun,Fan Tianfei,Pang Junling,Hou Yangfeng,Feng Xiaohang,Li Bolun,Ge Weipeng,Fan Tianhui,Zhang Tiantian,Lu Jiakai,Jing He,Jin Mu,Yan Chen,Wang Jing 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
Abdominal aortic aneurysm (AAA) is a permanent expansion of the abdominal aorta that has a high mortality but limited treatment options. Phosphodiesterase (PDE) 4 family members are cAMP-specific hydrolyzing enzymes and have four isoforms (PDE4A-PDE4D). Several pan-PDE4 inhibitors are used clinically. However, the regulation and function of PDE4 in AAA remain largely unknown. Herein, we showed that PDE4D expression is upregulated in human and angiotensin II-induced mouse AAA tissues using RT-PCR, western blotting, and immunohistochemical staining. Furthermore, smooth muscle cell (SMC)-specific Pde4d knockout mice showed significantly reduced vascular destabilization and AAA development in an experimental AAA model. The PDE4 inhibitor rolipram also suppressed vascular pathogenesis and AAA formation in mice. In addition, PDE4D deficiency inhibited caspase 3 cleavage and SMC apoptosis in vivo and in vitro, as shown by bulk RNA-seq, western blotting, flow cytometry and TUNEL staining. Mechanistic studies revealed that PDE4D promotes apoptosis by suppressing the activation of cAMP-activated protein kinase A (PKA) instead of the exchange protein directly activated by cAMP (Epac). Additionally, the phosphorylation of BCL2-antagonist of cell death (Bad) was reversed by PDE4D siRNA in vitro, which indicates that PDE4D regulates SMC apoptosis via the cAMP-PKA-pBad axis. Overall, these findings indicate that PDE4D upregulation in SMCs plays a causative role in AAA development and suggest that pharmacological inhibition of PDE4 may represent a potential therapeutic strategy.
ScienceON
KISS연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
