http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Clinical and Laboratory Findings of Pigmented Purpuric Dermatoses
( Muzeyyen Gonul ),( Seray Kulcu Cakmak ),( Nimet Ozcan ),( Isil Deniz Oguz ),( Ulker Gul ),( Zeynep Bıyıkll ) 대한피부과학회 2014 Annals of Dermatology Vol.26 No.5
Background: Pigmented purpuric dermatoses (PPD) are chronic, recurrent group of disorders characterized by petechial and pigmentary macules usually localized on the lower limbs. Its etiopathogenesis is unknown. There are very few clinical and etiological studies on PPD in the literature. Objective: We aim to examine the etiopathogenetic factors of PPD retrospectively. Methods: Demographic characteristics, history of co-morbid disorders and drug usage, hepatitis markers, levels of serum lipids, findings of Doppler ultrasonography in lower extremities, and patch test resultsof the 24 patients of PPD were examined retrospectively. The patch test results, history of drug use, and co-morbid disorders of the patients were compared with those of thecontrol groups. Results: The male-to-female ratio was 1 : 2, and 83.3% of the patients had Schamberg disease. Seventeen patients had co-morbid disorders and 16 used various drugs, but there was no statistically significant difference between the controls and patients. One patient was positive for hepatitis B surface antigen and 1, for anti-hepatitis C virus antibody. Nine had elevated total cholesterol levels, and 5 had elevated triglyceride levels. Further, 30% of them were positive for at least 1 allergen, while 16% of the controlsubjects were positive for at least 1 allergen, but statistically significant difference was not found between the 2 groups. Variable degrees of venous insufficiency were detected in 75% of the patients on Doppler ultrasonography of the lower extremities. Conclusion: Venous insufficiency and hypercholesterolemiamight be the basic predisposing factors for PPD. Further studies are needed to show if diabetes mellitus and hypertension may cause perivascular inflammation in PPD. (Ann Dermatol 26(5) 610∼614, 2014)
( Basak Yalcın ),( Seray Cakmak ),( Betul Yıldırım ) 대한피부과학회 2015 Annals of Dermatology Vol.27 No.4
Acute generalized exanthematous pustulosis (AGEP) is a cutaneous reaction principally induced by drugs. Spontaneous resolution is observed in most patients. However, severe cases required systemic corticosteroid administration. Hydroxychloroquine, which is used to treat some dermatologic and rheumatologic diseases because of its anti-inflammatory and immunosuppressive effects, is an uncommon cause of AGEP. A 67-year-old female patient presented with severe AGEP due to hydroxychloroquine treatment. She was recalcitrant to supportive care and systemic corticosteroid treatment butwas successfully treated with cyclosporine. Hydroxychloroquine-induced AGEP occurs in women with underlying rheumatologic diseases, has a longer latent period, and has a severe course usually requiring systemic treatment. (Ann Dermatol 27(4) 431∼434, 2015)
CASE REPORT : Two Cases of Unilateral Lichen Planus Following the Lines of Blaschko
( Derya Yayla ),( Seray Kulcu Cakmak ),( Isıl Deniz Oguz ),( Muzeyyen Gonul ),( Esra Ozhamam ),( Aysel Colak ),( Ulker Gul ) 대한피부과학회 2014 Annals of Dermatology Vol.26 No.5
A 50-year-old man and 71-year-old woman presented to ourclinic with unilateral, linear, erythematous, pruritic lesions along the lines of Blaschko. On the basis of clinical andhistopathological findings, the lesions were diagnosed as lichen planus with a Blaschkoian distribution, which is a rare form of lichen planus. The patients were treated with topical corticosteroids and antihistamines. (Ann Dermatol 26(5) 636 ∼638, 2014)