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Han, Sanghoon,Han, Kyoung Hee Korean Society of Pediatric Nephrology 2019 Childhood kidney diseases Vol.23 No.2
Bilateral renal obstruction is a rare critical condition, requiring a prompt diagnostic approach and treatment to restore the renal function. The most commonly observed obstructive uropathy in children is congenital malformation, such as posterior urethral valves and bilateral ureteropelvic junction obstruction. Malignant pelvic masses obstructing the ureter are widely reported in adults but are rarely observed in children. The treatment of ureteral obstruction related to pelvic malignancy is a therapeutic challenge with a median survival duration of 3-7 months in adults; however, pediatric patients with pelvic malignancy leading to ureteral obstruction had better outcomes, with a reported 5-year mortality rate of 20%, than the adult patients. Here, we report a rare case of bilateral ureteral obstruction associated with pelvic rhabdomyosarcoma presenting with acute kidney injury treated by ureteral diversion with double J stent, and concommittent emergency hemodialysis, leading to restoration of good renal function. We suggest that bilateral ureteral obstruction should be released as soon as possible using surgical or interventional approach to minimize the obstruction period, and subsequential chemotherapy may contribute to improvement of survival and recovery of renal function.
Sanghoon Han(한상훈) 한국인지과학회 2009 인지과학 Vol.20 No.3
이전의 연구들이 외부 피드백 정보에 대한 반응민감도에 성격특성적 개인차가 반영된다는 사실을 밝힌바 있지만, 재인기억과 관련한 의사결정에서 이러한 기질 혹은 특성적 개인차가 어떻게 관여하는지는 아직 알려진 바가 없다. 본 연구는 재인기억 과제에서 피드백에 근거한 의사결정 준거의 순응적 변화정도와 피드백에 대한 일반적 반응민감도의 개인차간 관계를 살펴보았다. 통제 조건인 실험 1에서는 올바른 피드백 조건이 의사결정 준거의 유동성에 영향을 미치지 않음을 보인 반면 피드백 조작이 이루어진 실험 2에서는 확신도가 높은 오기억 반응에만 선택적으로 편향된 피드백이 주어졌음에도 전반적인 Old/New 반응 범주의 결정준거 또한 순응적으로 이동함이 나타났다. 보다 중요하게 이 피드백에 근거한 의사결정 준거 학습에 나타나는 개별 피험자들의 반응민감도 차이가 강화 추구 혹은 불안 회피와 밀접하게 관련된 안정적 성격(Behavioral Activation System-BAS 혹은 Behavioral Inhibition System-BIS)의 개인차에 의해 유의미하게 예측될 수 있음이 나타났다. 이러한 결과는 그동안 외현적인 재인 기억 의사 결정에 있어서 중요하게 여기지 않았던 점증적 강화학습 기제가 결정 준거의 설정에 관여할 수 있음을 보여준다는 데에서 중요한 의미를 찾을 수 있다. Although it is known that there are personality characteristic variances in the sensitivity to environmental feedback, the trait individual difference has scarcely been explored in the context of recognition memory decision. The present study investigated this issue by examining the relationship between the feedback-based adaptive flexibility of recognition criterion positioning and personality differences in general sensitivity to non-laboratory outcomes. Experiment 1 demonstrated that veridical feedback itself had little effect on the recognition decision criterion whereas Experiment 2 demonstrated that biased feedback manipulations selectively restricted to high confidence errors, induced shifts even in the overall Old/New category criterion. Critically, individual differences in stable personality characteristic linked to reward seeking(Behavioral Activation System-BAS) and anxiety avoidance (Behavioral Inhibition System-BIS) has been shown to predict the sensitivity of subjects to this form of feedback-induced criterion learning. This data further support the idea that incremental reinforcement-based learning mechanism not often considered important during explicit recognition decisions may play a key role in criterion setting.
자동차용 Head Up Display의 LED 방열시스템 최적화에 관한 연구
한상훈(Sanghoon Han),이명래(Myungrae Lee),한영훈(Yeonghoon Han),노종원(Jongwon Noh),박종현(Jonghyun Park) 한국자동차공학회 2017 한국자동차공학회 부문종합 학술대회 Vol.2017 No.5
This paper is an experimental study of topology optimization and sensitivity analysis for considering conduction heat transfer in a LED thermal management. An optimization example is examined for PCB shape of LED Module of Head Up Display in order to design a heat exchanger as verification. Especially, we simulated the finite element model of the LED PCB and found out the thermal pattern area in which thermal via hole can have influence on the heat dissipation characteristic. The result remarkably shows that changing the topology of PCB Pattern can increase the total heat dissipation performance. The result is verified by the heat dissipation experiments in a real thermal environment of Head Up Display.
한상훈(Sanghoon Han),김성구(Sungku Kim),최환석(Hwanseok Choi) 한국추진공학회 2016 한국추진공학회 학술대회논문집 Vol.2016 No.12
액체로켓 엔진 연소기의 유동박리 및 측면하중 계산을 위한 이차원 축대칭 전산해석을 수행하였다. 설계점 및 탈설계점(OD#1)에서 해석을 수행하여 노즐 플룸 구조를 확인하였고 설계점 및 탈설계점(OD#1)에서는 유동박리가 발생하지 않음을 확인하였다. 구동압력비에 따른 플룸 형태 및 유동박리 현상을 파악하기 위하여 구동압력비 10부터 65까지 계산을 수행하였다. 본 연소기의 경우 낮은 구동압력비에서 자유충격파 박리만 발생하고 제한충격파 박리는 발생하지 않을 것으로 예측되었다. 자유충격파 박리에 의한 측면하중을 계산하기 위해 Schmucker에 의해 제안된 모델을 적용하여 보았다. Two dimensional axi-symmetry numerical analysis was conducted to compute side load and flow separation of liquid rocket engine combustor. Nozzle plume structures without flow separation were confirmed at design point and off design point(OD#1). To understand plume structure and flow separation phenomenon for the combustor nozzle, computations from NPR=10 to NPR=65 were conducted. In case of this combustor nozzle, it was predicted that free shock separation was just occurred at low NPR without restricted shock separation. In order to compute side load by free shock separation, the model suggested by Schmucker was applied.
한상훈(Sanghoon Han),조미옥(Miok Joh),김성구(Seong-Ku Kim),최환석(Hwan-Seok Choi) 한국추진공학회 2014 한국추진공학회 학술대회논문집 Vol.2014 No.5
액체로켓엔진 연소기 재생냉각 채널의 연료 분기구조에 대한 설계 및 해석을 수행하였다. 구조 제작성 및 안정성을 고려한 분기구조를 설계하였고, 설계된 분기구조에 대해 전산 해석을 수행하여 분기구조에 의해 분배되는 연료의 상, 하류 분배량과 채널 내의 압력 손실을 평가하였다. 또한 복합 열전달 해석을 병행하여 연료에 의한 재생냉각 채널의 냉각 성능도 확인하였다. The design and analysis of fuel split structure for a liquid rocket engine combustor were performed. The fuel split structure was designed in order to satisfy manufacturing and thermal stabilization. Through CFD analyses, distribution ratio between upstream and downstream of fuel was predicted. And pressure loss in regenerative cooling channel were evaluated. In addition, cooling performance of regenerative cooling channel was confirmed by conjugated heat transfer computation.