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Naoki Mori,Naoko Yoshinaga 한국응용곤충학회 2013 한국응용곤충학회 학술대회논문집 Vol.2013 No.04
Fatty acid-amino acid conjugates (FACs), first identified from beet armyworm Spodoptera exigua larvae (Alborn et al., 1997), have been found in noctuid as well as sphingid caterpillar oral secretions and especially volicitin [N-(17-hydroxylinolenoyl)- L-glutamine, 17OH-volicitn] and its biochemical precursor, N-linolenoyl- L-glutamine, are known elicitors of induced volatile emissions in corn plants. We conducted FAC screening of 29 lepidopteran species and found FACs in 19 of these species (Yoshinaga & Mori et al., 2010). Thus, FACs are quite commonly synthesized through a broad range of lepidopteran caterpillars. From an evolutionary perspective, it is presumed that volicitin and the other FACs, although consequently unfavorable to the insect in the plant-herbivore interactions, are produced because they are essential part of the primary metabolism of the insects. In this context, we suggested that FACs in Spodoptera litura play an active role in nitrogen assimilation by regulating the amount of glutamine in the larval midgut (Yoshinaga & Mori et al., 2008). The benefits of the physiological function of FACs for the herbivores need to outweigh the costs caused by induction of plant defense
Allergenicity of simple chemicals in house dust mites detected by patch tests
Hideo Nakayama,Akiko Kumei,Naoki Mori,Yasumasa Kuwahara 한국응용곤충학회 2008 한국응용곤충학회 학술대회논문집 Vol.2008 No.10
Eczema due to contact allergy is usually produced by simple chemicals with the molecules less than 500 KD. A total of 100 cultivated house dust mites (HDM) were extracted with their lipid components in hexane, and they were analyzed by mass measuring gas chromatography. The same components were mixed in petrolatum at 5% or less, and patch tested using Finn Chambers, and the results were read by ICDRG standards. α-Acaridial, contained in Tyrophagus putrescentiae, turned out to have been a primary sensitizer, and could make prurigo reactions. Geranial, a main lipid component in dermatophagoides, showed positive rates at 58.8% at 5% concentration in atopic dermatitis and was expected to cross react to geraniol in cosmetics and soaps. It means that when one is sensitized by HDM, eczema can be provoked and maintained by the usage of ordinary soaps, shampoos and cosmetics, containing geraniol.
Valsalva Aneurysm Filled with Thrombi Mimicking a Cardiac Tumor
Yasuharu Lee,Naoki Mori,Daisuke Nakamura,Takahiro Yoshimura,Masayuki Taniike,Nobuhiko Makino,Hiroyasu Kato,Yasuyuki Egami,Ryu Shutta,Jun Tanouchi,Yoshio Yamada,Masami Nishino 대한심장학회 2012 Korean Circulation Journal Vol.42 No.12
A Valsalva aneurysm filled with thrombi can be difficult to diagnose, because it mimics a cardiac tumor. Both cardiac magnetic resonance imaging (MRI) and transesophageal echocardiogram (TEE) were performed on a patient who showed a low-echoic mass located between the atrial septum and the non-coronary sinus. Based on MRI findings allowing tissue characterization and the accurate location of the mass and the TEE findings of an irregular surface of the mass and a partial defect in the edge of the non-coronary sinus, we diagnosed the mass as a thrombosed Valsalva aneurysm that had perforated the inter-atrial septum. The operative findings coincided with the preoperative di-agnosis. Both MRI and TEE are useful for diagnosing this condition.
Hideyuki Tamai,Naoki Shingaki,Yoshiyuki Mori,Kosaku Moribata,Akira Kawashima,Yoshimasa Maeda,Toru Niwa,Hisanobu Deguchi,Izumi Inoue,Takao Maekita,Mikitaka Iguchi,Jun Kato,Masao Ichinose 거트앤리버 소화기연관학회협의회 2016 Gut and Liver Vol.10 No.4
Background/Aims: This study aimed to predict sustained viral response (SVR) to low-dose pegylated interferon (PEGIFN) plus ribavirin of elderly and/or cirrhotic patients with genotype 2 hepatitis C virus (HCV) using viral response within 2 weeks. Methods: Low-dose PEG-IFN-α-2b plus ribavirin was administered to 50 elderly and/or cirrhotic patients with genotype 2 HCV for 24 weeks. The dynamics of HCV RNA and HCV core antigen levels within 2 weeks were measured. Results: The patients’ median age was 66 years. There were 21 male and 29 female patients. The median baseline HCV RNA level was 5.7 log IU/mL. Rapid viral response was achieved in 17 patients (34%), SVR in 28 (56%), and two (4%) discontinued treatment. Univariate analysis of factors contributing to SVR showed significant differences for sex, baseline virus level, and response within 4 weeks. When 40 fmol/L was set as the cutoff value for the core antigen level at 1 week, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy for predicting SVR were 93%, 75%, 84%, 88%, and 85%, respectively. Conclusions: Low-dose PEG-IFN plus ribavirin was a safe and costeffective treatment for elderly and/or cirrhotic patients with genotype 2 HCV, and the viral response within 2 weeks was a useful predictor of SVR.
Yasumasa Kuwahara,Naoki Mori,Kiminori Shimizu,Chihiro Tanaka,Mitusya Tsuda Korean Society of Applied Entomology 1998 Journal of Asia-Pacific Entomology Vol.1 No.1
Female sex pheromones, which elicit mounting behavior of conspecific males, were identified in 4 species of the genus Caloglyphus(Acarina: Acaridae). Although the sex pheromones are distributed over both males and femles, they could be classified into two groups; one is an adult-specific pheromone, and the other is one that is detectable even in nymphal stages. In addition, in the adult-specific species, the pheromonal content ratios of female to male were found to be larger than those observed in the nonspecific species. The two types of pheromonal distribution were compared with phylogenetic relationships based on a portion of the mitochondrial cytochrome oxidase subunit I(COI) gene in the four species. The polymerase chain reaction was used to amplify the COI from the four mites, with primers used in spider mites(Tetranychidae). Fragments of the COI(453bp) were obtained for the three species. The phylogenetic tree, based on the COI sequences, was inferred using a maximum parsimony method. Analysis of the pheromonal distribution within this phylogenetic framework agreed with the hypothesis that the mite sex pheromone evolved from a common compound, which originally fundtioned as a male sexual excitant, into a biologically active, sex linked specific one.
Innentitelbild: Hexaphyrin Fused to Two Anthracenes (Angew. Chem. 39/2012)
Naoda, Koji,Mori, Hirotaka,Aratani, Naoki,Lee, Byung Sun,Kim, Dongho,Osuka, Atsuhiro WILEY‐VCH Verlag 2012 Angewandte Chemie Vol.124 No.39
<P><I>π</I>‐expandierte Porphyrinoide in denen aromatische Strukturteile an den Porphyrinring kondensiert sind, rücken zunehmend in den Blickpunkt. In ihrer Zuschrift auf S. 9994 ff. berichten D. Kim, A. Osuka et al. über die Bildung eines Hexaphyrins, das mit zwei Anthracenylsubstituenten oxidativ kondensiert wurde. Das rechteckige konjugierte System verleiht dem kondensierten Hexaphyrin eine bemerkenswerte rotverschobene und eine ungewöhnlich scharfe Q‐Banden‐ähnliche Absorption bei 1467nm. (Photos: kyoto‐design.jp)</P>