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Changes in the Optogalvanic Signal Amplitude in a Hollow Cathode Discharge
Lee, Jun-Hoi,Koo, Kyung-Wan,Lee, Ki-Sik The Korean Institute of Electrical and Electronic 2009 Transactions on Electrical and Electronic Material Vol.10 No.6
The spatial distribution of the optogalvanic (OG) signal in argon at the 801.489 nm ($1s_5-2p_8$ transition at the metastable level in Paschen notation) was investigated in the radial direction of a hollow cathode discharge tube. The results of this experiment showed that the OG signal amplitude decreases in accordance with the following two conditions; first, the level of discharge current and second, the distance from the cathode dark space. These results can be quantified by analyzing the electron density profile along the discharge regions, which can directly influence the collisional ionization induced by electron impact.
Lee, Sang Jin,Heo, Dong Nyoung,Lee, Hak Rae,Lee, Donghyun,Yu, Seung Jung,Park, Su A,Ko, Wan-Kyu,Park, Se Woong,Im, Sung Gap,Moon, Ji-Hoi,Kwon, Il Keun The Royal Society of Chemistry 2015 Journal of materials chemistry. B, Materials for b Vol.3 No.26
<P>In the last decade, titanium has been effectively used in the dental field for oral surgery as an implant material. However, disinfected Ti can be easily re-infected by the surrounding environment. Thus, a novel anti-fouling treatment for Ti implants is currently necessary. In this study, we designed an anti-fouling surface comprised of poly<I>N</I>-isopropylacylamide (PIPAAM) grafted Ti by introducing poly glycidyl methacrylate (pGMA) coating<I>via</I>an initiated chemical vapor deposition (iCVD) system to prevent bacterial infection. The results indicate that pristine Ti was well coated with pGMA with a film thickness of approximately 60 nm and uniformly grafted with PIPAAM. The bacteria were effectively detached after rinsing with a buffer solution at room temperature, while hADSCs were well attached on the surface treated Ti surface at oral temperature. All tests clearly confirm that our strategy may be a useful means of imparting anti-fouling characteristics to Ti in order to prevent bacterial adhesion and resultant peri-implantitis.</P>
Lee, Sang Jin,Heo, Dong Nyoung,Moon, Ji-Hoi,Park, Ha Na,Ko, Wan-Kyu,Bae, Min Soo,Lee, Jung Bok,Park, Se Woong,Kim, Eun-Cheol,Lee, Chang Hoon,Jung, Bock-Young,Kwon, Il Keun American Scientific Publishers 2014 Journal of nanoscience and nanotechnology Vol.14 No.10
<P>Electrospun chitosan (CTS) nanofibers have been well known for use as a wound dressing in the biomedical field. Nevertheless, fatal bacterial infections are still a serious problem when CTS nanofibers are used for wound treatment. In this study, we designed a novel wound dressing based on blending the chitosan with polyurethane (CTS/PU) containing silver sulfadiazine (AgSD) in order to enhance both antibacterial activity and mechanical strength. This fiber sheet was produced using the electrospinning (ELSP) technique. The CTS/PU containing AgSD fiber sheet was characterized by energy-dispersive X-ray spectroscopy (EDX). The physicochemical properties of the CTS/PU/AgSD fiber sheets were also characterized by thermogravimetric analysis (TGA) and Fourier transform infrared spectroscopy (FT-IR). The electrospun fibers were morphologically characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). For an in vitro evaluation, the CTS/PU/AgSD fiber sheets were tested for their antibacterial activity against gram-negative Pseudomonas aeruginosa (P. aeruginosa), gram-positive Staphylococcus aureus (S. aureus) and Methicillin-resistant Staphylococcus aureus (MRSA). The results indicate that CTS/PU/AgSD fiber sheets have strong antimicrobial activity as displayed by inhibition of bacterial growth and prevention of infection during the healing process. These results indicate that this material would be good for use as a wound dressing material.</P>
Noh, Wan-Woo,Lee, Sin-Hyung,Lee, Gyujeong,Lee, In-Ho,Park, Hea-Lim,Kim, Min-Hoi,Lee, Sin-Doo American Scientific Publishers 2016 Journal of nanoscience and nanotechnology Vol.16 No.8
<P>We demonstrated the effect of the hydrophobicity of a gate insulator on the bias stress in a solution-processed organic thin-film transistor (OTFT). Without changing the surface morphology, only the hydrophobicity of the gate insulator was systematically tailored to achieve the electrical stability of the OTFT against the bias stress. The shift of the threshold voltage (V-TH) by the gate bias stress was found to decrease with increasing the hydrophobicity of the gate insulator. The shift of V-TH in the optimized OTFT was as small as -1.09 V under the gate bias stress for 1000 s.</P>
Lee, Jun Ho,Kim, Jie Wan,Ko, Na Young,Mun, Se Hwan,Her, Erk,Kim, Bo Kyung,Han, Jeung Whan,Lee, Hoi Young,Beaven, Michael A.,Kim, Young Mi,Choi, Wahn Soo Elsevier 2008 The journal of allergy and clinical immunology Vol.121 No.5
<P><B>Background</B></P><P>Activation of mast cells through the high-affinity receptor for IgE (FcϵRI) underlies atopic allergic reactions. Curcumin can block this activation, but the mechanism and the effects of curcumin on IgE-mediated allergic reactions are unknown.</P><P><B>Objectives</B></P><P>We sought to determine the antiallergic activity of curcumin <I>in vivo</I> and its mechanism of action in mast cells.</P><P><B>Methods</B></P><P>The antiallergic activity of curcumin was evaluated in mast cell cultures and the passive cutaneous anaphylaxis model. The effects of curcumin on mast cell signaling events were examined by using immunoblotting, immunoprecipitation, RT-PCR, and other molecular biologic approaches.</P><P><B>Results</B></P><P>Curcumin inhibited antigen-mediated activation of mast cells and passive cutaneous anaphylaxis in mice. Suppression of degranulation and secretion of TNF-α and IL-4 was apparent at concentrations as low as 3 μmol/L curcumin in activated mast cells. Similar concentrations of curcumin suppressed Syk-dependent phosphorylations of the adaptor proteins linker of activated T cells and Grb2-associated binder 2, which are critical for mast cell activation. Although curcumin did not inhibit the phosphorylation of Syk itself, it directly inhibited Syk kinase activity <I>in vitro</I>. Further downstream, activating phosphorylations of Akt and the mitogen-activated protein kinases p38, p44/42 (extracellular signal-regulated kinase 1/2), and c-Jun N-terminal kinase, which are critical for the production of inflammatory cytokines, were also inhibited.</P><P><B>Conclusions</B></P><P>Curcumin inhibits Syk kinase–dependent signaling events in mast cells and might thus contribute to its antiallergic activity. Therefore curcumin might be useful for the treatment of mast cell–related immediate and delayed allergic diseases.</P>
잘 훈련된 운동 선수와 훈련되지 않은 성인의 근육 효소 비교
이규훈,황치문,김용걸,김성수,최현진,김혜완,김민석,김희상,안경회,송종일 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.2
Objective : The muscle enzymes which are CPK, LDH, and AST were increased during exercise and after exercise in blood and tissues. There is substaintial evidence that CPK, LDH, AST rise less in well physical trained men than untrained after exercise. But were not known well trained men base line level of CPK, LDH and AST. Therefore we would evaluate the difference of base line of CPK, LDH and AST between well trained men, national level athlete, and untrained men. Method : Control group was composed of 138 men and 146 women not taking any particular training. Trained athletes were divided upon amount of exercise. Experimental group 1 that took relatively less amount of exercise was composed of 34 national level shooting men athlete and 17 women. Experimental group 2 that took relatively more amount of exercise was composed of 25 national level judo men athlete and 19 women. We measured CPK, LDH and AST in the serum of control group and experimental group 1 and 2 after 16 hours rest. Result : CPK and LDH were significantly increased in the experimental group 1 and 2 compared to the control group(p<0.05). but AST were not significantly increased in the experimental group 1 and 2 compared to the control group(p<0.05). Conclusion : In order to understand between the base line level of muscle enzyme and training effect, more extensive long-term study would be necessary.