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MULTI-JOINT ACTIVE CATHETER BASED ON SILICON MICROMACHINING
Lim, Geunbae,Minami, Kazuyuki,Sugihara, Masahisa,Uchiyama, Masaru,Esashi, Masayoshi 경북대학교 센서기술연구소 1994 센서技術學術大會論文集 Vol.5 No.1
We developed multi-joint active catheter based on silicon micromachining technique. Active catheter having sensors, and actuators can be used for medical purposes as interventional therapy. It consists of several segment-units and joints which have micro Shape Memory Alloy (SMA) actuators for bending movements. As this active catheter has multi-joint structure, it can bend actively and conform to the shape of narrow blood vessels. The outer diameter of the fabricated catheter is 3mm and the movable angle of each joint was 20 degree. SMA actuators are indirectly heated by surrounding heater element that is nickel thin film. This indirect heating method was more compatible than direct heating with built-in driving integrated circuits because of the high resistance of the thin film heater. We used silicon batch fabrication for the segment-unit to minimize assembly processes. Electrical connection between the segment-unit and the SMA actuator was implemented by UV (Ultra Violet) curing conductive resin to avoid the heating of the SMA during assembly process.
Jeon, Hyungkook,Kim, Suhyeon,Lim, Geunbae Elsevier 2018 MICROELECTRONIC ENGINEERING Vol.198 No.-
<P><B>Abstract</B></P> <P>Cell lysis and the separation of intracellular components are key steps in the analysis of intracellular components. Advances in micro-electro-mechanical system (MEMS) technologies have prompted a number of investigations into the potential applications of microfluidics to the development of cell lysis and sample separation methods. The electrical force is considered to have excellent potential for parallelizing and automating cell lysis and sample separation methods. In this review, we focus on research works related to electrical force-based continuous cell lysis and sample separation techniques. We provide brief explanations of the major developed techniques and summarize their advantages and limitations with respect to their applicability as a part of integrated microfluidic cell analysis system.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We summarize and classify continuous electrical force lysis and separation methods. </LI> <LI> We describe their strengths and weaknesses in comparison to other methods. </LI> <LI> We focus on analyzing their applicability to integrated cell analysis systems. </LI> <LI> This review provides useful insight about integrated cell analysis systems. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Cell behaviour on a polyaniline nanoprotrusion structure surface
Nam, Hyoryung,An, Taechang,Lim, Geunbae Springer 2014 NANOSCALE RESEARCH LETTERS Vol.9 No.1
<P>The extracellular matrix provides mechanical support and affects cell behaviour. Nanoscale structures have been shown to have functions similar to the extracellular matrix. In this study, we fabricated nanoprotrusion structures with polyaniline as cell culture plates using a simple method and determined the effects of these nanoprotrusion structures on cells.</P>
A Novel SPM Probe with MOS Transistor and Nano Tip for Surface Electric Properties
Lee, Sang H,Lim, Geunbae,Moon, Wonkyu Institute of Physics Publishing Ltd 2007 Journal of Physics: Conference Series Vol.61 No.1
<P>In this paper, the novel SPM (Scanning Probe Microscope) probe with the planar MOS (Metal-Oxide-Semiconductor) transistor and the FIB (Focused Ion Beam) nano tip is fabricated for the surface electric properties. Since the MOS transistor has high working frequency, the device can overcome the speed limitation of EFM (Electrostatic Force Microscope) system. The sensitivity is also high, and no bulky device such as lock-in-amplifier is required. Moreover, the nano tip with nanometer scale tip radius is fabricated with FIB system, and the resolution can be improved. Therefore, the probe can rapidly detect small localized electric properties with high sensitivity and high resolution. The MOS transistor is fabricated with the common semiconductor process, and the nano tip is grown by the FIB system. The planar structure of the MOS transistor makes the fabrication process easier, which is the advantage on the commercial production. Various electric signals are applied using the function generator, and the measured data represent the well-established electric properties of the device. It shows the promising aspect of the local surface electric property detection with high sensitivity and high resolution.</P>