http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Sustainability in Manufacturing and Factories of the Future
Christoph Herrmann,Christopher Schmidt,Denis Kurle,Stefan Blume,Sebastian Thiede 한국정밀공학회 2014 International Journal of Precision Engineering and Vol.1 No.4
An increasing global demand for natural resources and the inherent challenges accompanying this demand pose a great task for manufacturing companies. Apart from this, new technologies and a demographic change of the workforce as well as the desire for new individualized products make manufacturing more challenging than ever. To succeed in this new setting manifold perspectives of a factory have been proposed in order to enhance the understanding of the complex interdependencies between the factory elements. Against this background, this paper starts with a short overview regarding the paradigm change in manufacturing including contemporary trends triggering the requirements for factories of the future. Subsequent to that, a selection of factory perspectives is revised indicating the demand for a new holistic perspective of a factory that is more suitable with respect to the new trends. For that reason a new holistic perspective on the factory of the future is presented.
A Methodology for Customized Prediction of Energy Consumption in Manufacturing Industries
Christopher Schmidt,Wen Li,Sebastian Thiede,Sami Kara,Christoph Herrmann 한국정밀공학회 2015 International Journal of Precision Engineering and Vol.2 No.2
Regulative measures and rising energy cost foster the trend towards energy efficient manufacturing. However, companies are facing hurdles such as high effort and little expertise when implementing energy efficiency measures. Moreover, the embodied energy of products cannot be determined accurately in eco-assessments of factories. This paper presents a methodology for the reliable prediction of energy consumption of arbitrary manufacturing processes. It is based on minimal measurements and requires little effort and previous knowledge due to precise guidelines. Consumption models help to allocate energy cost to products, to calculate the product carbon footprint and to derive and validate measures to improve energy efficiency in production. The methodology has been applied in a medium size company with a large number of different products and machines.
Schmidt, Slawa,Piglosiewicz, Bj?rn,Sadiq, Diyar,Shirdel, Javid,Lee, Jae Sung,Vasa, Parinda,Park, Namkyoo,Kim, Dai-Sik,Lienau, Christoph American Chemical Society 2012 ACS NANO Vol.6 No.7
<P>We demonstrate adiabatic nanofocusing of few-cycle light pulses using ultrasharp and ultrasmooth single-crystalline gold tapers. We show that the grating-induced launching of spectrally broad-band surface plasmon polariton wavepackets onto the shaft of such a taper generates isolated, point-like light spots with 10 fs duration and 10 nm diameter spatial extent at its very apex. This nanofocusing is so efficient that nanolocalized electric fields inducing strong optical nonlinearities at the tip end are reached with conventional high repetition rate laser oscillators. We use here the resulting second harmonic to fully characterize the time structure of the localized electric field in frequency-resolved interferometric autocorrelation measurements. Our results strongly suggest that these nanometer-sized ultrafast light spots will enable new experiments probing the dynamics of optical excitations of individual metallic, semiconducting, and magnetic nanostructures.</P>
Black-Box Accuracy Compensation for a Cable-Driven Parallel Robot
Valentin Schmidt,Werner Kraus,Christoph Martin,Xuejun Jin,Andreas Pott 제어로봇시스템학회 2017 제어로봇시스템학회 국제학술대회 논문집 Vol.2017 No.10
This paper presents the findings of experiments done to increase the accuracy of a fully constrained cabledriven parallel robot with 8 cables and 6 degrees of freedom. Measurements were conducted using a Laser Tracker in 3 dof and the position accuracy mapped. Measurements were performed in a grid with 1920 points. From the measurement data distortion to the actual desired position is measured and using a linear approximation subsequent trajectories are compensated for any systematic errors. On an example robot, this black box correction brought an average improvement from 10.6 mm distance to the desired point to 2.47 mm distance from the desired point. This is a significant improvement m accuracy.
Observing the localization of light in space and time by ultrafast second-harmonic microscopy
Mascheck, Manfred,Schmidt, Slawa,Silies, Martin,Yatsui, Takashi,Kitamura, Kokoro,Ohtsu, Motoichi,Leipold, David,Runge, Erich,Lienau, Christoph Springer Science and Business Media LLC 2012 Nature photonics Vol.6 No.5
( Henusha D. Jhundoo ),( Tobias Siefen ),( Alfred Liang ),( Christoph Schmidt ),( John Lokhnauth ),( Brice Moulari ),( Arnaud B. Duneau ),( Yann Pellequer ),( Crilles Casper Larsen ),( Alf Lamprecht ) 한국응용약물학회 2021 Biomolecules & Therapeutics(구 응용약물학회지) Vol.29 No.5
5-amino salicylic acid (5-ASA) is a standard therapy for the treatment of mild to moderate forms of inflammatory bowel diseases (IBD) whereas more severe forms involve the use of steroids and immunosuppressive drugs. Hyaluronic acid (HA) is a naturally occurring non-sulfated glycosaminoglycan that has shown epithelium protective effects in experimental colitis recently. In this study, both 5-ASA (30 mg/kg) and HA (15 mg/kg or 30 mg/kg) were administered rectally and investigated for their potential complementary therapeutic effects in moderate or severe murine colitis models. Intrarectal treatment of moderate and severe colitis with 5-ASA alone or HA alone at a dose of 30 mg/kg led to a significant decrease in clinical activity and histology scores, myeloperoxidase activity (MPO), TNF-α, IL-6 and IL-1β in colitis mice compared to untreated animals. The combination of HA (30 mg/kg) and 5-ASA in severe colitis led to a significant improvement of colitis compared to 5-ASA alone. Combined rectal therapy with HA and 5-ASA could be a treatment alternative for severe cases of IBD as it was the only treatment tested that was not significantly different from the healthy control group. This study further underlines the benefit of searching for yet unexplored drug combinations that show therapeutic potential in IBD without the need of designing completely new drug entities.