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Advancing Cardio-Oncology in Asia
Choon Ta Ng,Li Ling Tan,Il Suk Sohn,Hilda Gonzalez Bonilla,Toru Oka,Teerapat Yinchoncharoen,Wei-Ting Chang,Jun Hua Chong,Maria Katrina Cruz Tan,Rochelle Regina Cruz,Astri Astuti,Vivek Agarwala,Van Chi 대한심장학회 2023 Korean Circulation Journal Vol.53 No.1
Cardio-oncology is an emerging multi-disciplinary field, which aims to reduce morbidity and mortality of cancer patients by preventing and managing cancer treatment-related cardiovascular toxicities. With the exponential growth in cancer and cardiovascular diseases in Asia, there is an emerging need for cardio-oncology awareness among physicians and country-specific cardio-oncology initiatives. In this state-of-the-art review, we sought to describe the burden of cancer and cardiovascular disease in Asia, a region with rich cultural and socio-economic diversity. From describing the uniqueness and challenges (such as socio-economic disparity, ethnical and racial diversity, and limited training opportunities) in establishing cardio-oncology in Asia, and outlining ways to overcome any barriers, this article aims to help advance the field of cardio-oncology in Asia.
Proposal of a Novel Lung Fibrosis Scoring System for Post-COVID-19 Lung Fibrosis Patients
( Seo Hee Yang ),( Eun-ju Park ),( Hyung-jun Kim ),( Myung Jin Song ),( Yeon Wook Kim ),( Byung Soo Kwon ),( Sung Yoon Lim ),( Yeon-joo Lee ),( Jong Sun Park ),( Ho Il Yoon ),( Jae Ho Lee ),( Choon-ta 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.0
Background The usefulness of lung ultrasound (LUS) in the initial test for coronavirus disease 2019 (COVID-19) was already known, but ultrasound assessment of pulmonary fibrosis after intensive care for COVID-19 is not elucidated. We aimed to suggest new lung fibrosis scoring system and determine whether they correlate with traditional radiographic findings. Furthermore, we examined the usefulness of hand-held ultrasound at outpatient clinic in the evaluation of pulmonary complications of post- COVID-19 patients after recovery. Methods Severe COVID-19 patients who need for mechanical ventilation in intensive care unit were enrolled prospectively. All patients underwent LUS (GE Vscan Extend™) scans on the day of admission, discharge, and follow-up visit about one month after discharge. If possible, high resolution computed tomography (HRCT) was also taken. In 12 pulmonary zones, the presence or absence of A-line, pleural effusion, lung sliding, and consolidation were observed, and total lung fibrosis score was assigned by giving a score according to the degree of markers that could reflect fibrosis, such as B-lines, pleural thickening, or consolidation. Results We currently enrolled eleven patients, one of whom has died, three are still in the ICU. So far, seven had underwent LUS before discharge and are expected to be followed up at outpatient clinic. The average numbers of B-lines was 2.31 [1.93-2.43]; pleural thickness (mm) 2.11 [1.91-2.34] in the initial stage, and at the stage before discharge, 0.29 [0.14-0.43] in B-lines 2.47 [2.30-2.56] in the pleural thickness, respectively. They will be followed up in an outpatient clinic one month later using a portable handheld ultrasound and the correlation of quantitative assessment by HRCT also analyzed. Conclusions We have presented a novel scoring system for the evaluation of pulmonary fibrosis in post-COVID patients. We suggest that LUS can be considered as the first-line tool in outpatient setting for follow-up of post-COVID lung fibrosis.