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( A. Cordova ),( W. A. King ),( G. F. Mastromonaco ) 한국축산학회(구 한국동물자원과학회) 2017 한국축산학회지 Vol.59 No.11
Over the past decades, in vitro culture media have been developed to successfully support IVF embryo growth in a variety of species. Advanced reproductive technologies, such as somatic cell nuclear transfer (SCNT), challenge us with a new type of embryo, with special nutritional requirements and altered physiology under in vitro conditions. Numerous studies have successfully reconstructed cloned embryos of domestic animals for biomedical research and livestock production. However, studies evaluating suitable culture conditions for SCNT embryos in wildlife species are scarce (for both intra- and interspecies SCNT). Most of the existing studies derive from previous IVF work done in conventional domestic species. Extrapolation to non-domestic species presents significant challenges since we lack information on reproductive processes and embryo development in most wildlife species. Given the challenges in adapting culture media and conditions from IVF to SCNT embryos, developmental competence of SCNT embryos remains low. This review summarizes research efforts to tailor culture media to SCNT embryos and explore the different outcomes in diverse species. It will also consider how these culture media protocols have been extrapolated to wildlife species, most particularly using SCNT as a cutting-edge technical resource to assist in the preservation of endangered species.
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Initial Report for the Radiation Effects Research Foundation F1 Mail Survey
Milder, CM,Sakata, R,Sugiyama, H,Sadakane, A,Utada, M,Cordova, KA,Hida, A,Ohishi, W,Ozasa, K,Grant, EJ Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.3
To study the full health effects of parental radiation exposure on the children of the atomic bomb survivors, the Radiation Effects Research Foundation developed a cohort of 76,814 children born to atomic bomb survivors (F1 generation) to assess cancer incidence and mortality from common adult diseases. In analyzing radiation-associated health information, it is important to be able to adjust for sociodemographic and lifestyle variations that may affect health. In order to gain this and other background information on the F1 cohort and to determine willingness to participate in a related clinical study, the F1 Mail Survey Questionnaire was designed with questions corresponding to relevant health, sociodemographic, and lifestyle indicators. Between the years 2000 and 2006, the survey was sent to a subset of the F1 Mortality Cohort. A total of 16,183 surveys were completed and returned: 10,980 surveys from Hiroshima residents and 5,203 from Nagasaki residents. The response rate was 65.6%, varying somewhat across parental exposure category, city, gender, and year of birth. Differences in health and lifestyle were noted in several variables on comparison across city and gender. No major differences in health, lifestyle, sociodemographics, or disease were seen across parental exposure categories, though statistically significant tests for heterogeneity and linear trend revealed some possible changes with dose. The data described herein provide a foundation for studies in the future.
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M. A. Vallejo,M. Perez,P. V. Ceron,R. Navarro,C. Villaseñor,T. Cordova,M. Sosa 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.12
Phosphate glasses doped with Dy3+ ions and containing silver nanoparticles (SNPs) were synthesized in the present work. We report photoluminescence characterization by absorption and emission spectra. The effect of Ag concentration on the thermoluminescence (TL) glow curves was studied. The scanning electron microscopy (SEM) shows the formation of SNP. Absorption spectra of the samples show the influence of the SNP in the bands 350 nm at 425 nm associated with the Dy3+, in the same spectra we can see the bands 750, 800, 875, 1098, 1278 nm and 1675 nm belonging to the Dy3+. Emission spectra show two prominent bands at 480 nm and 574 nm and one faint band at 665 nm corresponding to 4 F 9/2 → 6 H 15/2, 4 F 9/2 → 6 H13/2 and 4 F 9/2 → 6 H 11/2 transitions, respectively. All bands under 364 nm pumping, and the fluorescence in the 550 nm and 590 nm spectral range enhanced four times. The Commission Internationale de 1'Eclairage (CIE) color coordinates were evaluated from the emission spectra to simulate white light emission from the phosphate glasses. The photostability of the samples was also studied in the UVA (315–403 nm) and UVB (280–315 nm) ranges. TL due to ultraviolet radiation (UVR) was studied; the glow curves show significant dependence of the TL intensity with the increment of SNPs in the samples. These results show the phosphate glasses doped with Dy3+ and containing SNP as a potential candidate have to be used in solid-state illumination and retrospective dosimetry.
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Large-Pore Apertures in a Series of Metal-Organic Frameworks
Deng, H.,Grunder, S.,Cordova, K. E.,Valente, C.,Furukawa, H.,Hmadeh, M.,Gandara, F.,Whalley, A. C.,Liu, Z.,Asahina, S.,Kazumori, H.,O'Keeffe, M.,Terasaki, O.,Stoddart, J. F.,Yaghi, O. M. American Association for the Advancement of Scienc 2012 Science Vol.336 No.6084
<P>We report a strategy to expand the pore aperture of metal-organic frameworks (MOFs) into a previously unattained size regime (>32 angstroms). Specifically, the systematic expansion of a well-known MOF structure, MOF-74, from its original link of one phenylene ring (I) to two, three, four, five, six, seven, nine, and eleven (II to XI, respectively), afforded an isoreticular series of MOF-74 structures (termed IRMOF-74-I to XI) with pore apertures ranging from 14 to 98 angstroms. All members of this series have noninterpenetrating structures and exhibit robust architectures, as evidenced by their permanent porosity and high thermal stability (up to 300C). The pore apertures of an oligoethylene glycol-functionalized IRMOF-74-VII and IRMOF-74-IX are large enough for natural proteins to enter the pores.</P>
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