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Xie Zhenlian,Jiao Jianling,Liu Huimin 한국경영교육학회 2012 한국경영교육학회 학술발표대회논문집 Vol.2012 No.6
The paper uses economic value added (EVA) as a tool to analyze whether foreign-capital merger and acquisition (M&A) can effectively improve the performance of listed companies in China and the impact degree of the type of foreign-capital M&A on its performance, which will provide investment decision support for a listed company before its acquisition in order to achieve the rational use of foreign capital to integrate the resources. Using the modified EVA system, the paper compares vertically and analyzes the performance of M&A listed companies by foreign capital during 2003-2006 according to one year before, the year, one year after, and two years after the foreign-capital M&A, and examines the performance before and after M&A of the listed companies of horizontal, vertical and mixed M&A to verify whether foreign-capital M&A can bring value creation for listed companies in China. The results show that all the sample companies'average EVA is increased year by year after M&A from one year before to two years after the M&A. Foreign-capital M&A activities helps to improve the performance of the listed companies, and it creates value for the company; Different types of M&A results in different M&A performance, seeing from the average EVA, horizontal M&A companies'performance is increased year by year in the three years from the year before to the year after M&A, which demonstrates horizontal M&A can promote the company's development by scale economy effect in a short of time and create M&A value. The performance of vertical M&A and mixed M&A companies are all first decreased then increased,"@which shows that performanceproducing needs a process for both the vertical M&A focusing on the transaction costs reduce and the mixed M&A designed to achieve diversification operations of the company, in this process, the company's performance may even fall down temporarily. Both vertical M&A and mixed M&A have certain of risk, the successfully integration after M&A is the key to the expected effects. Through internal market transactions, vertical M&A can expedite supply and marketing channels, reduce the uncertainty of risk and cost, obtain the purpose of enhancing the stability of company development; while through diversification operations, mixed M&A can realize industry transformation of the company to foster new earnings point, thus disperse risk, and improve corporate performance.
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Identification and characterization of scirr1, a novel geneup-regulated after spinal cord injury
Tao Liu,Zhenlian Ma,Haiping Que,Xin Li,Yanli Ni,Shuqian Jing,Shaojun Liu 생화학분자생물학회 2007 Experimental and molecular medicine Vol.39 No.3
Spinal cord injury and regeneration involves trans-criptional activity of many genes, of which many remain unknown. Using the rat spinal cord full- transection model, bioinformatics, cloning, expres-sion assays, fusion proteins, and transfection techniques, we identified and characterized one such differentially expressed gene, termed scirr1 (spinal cord injury and/or regeneration related gene 1). Fourteen orthologs were found in 13 species from echinoderm to insect and human by Blast search of NCBI protein reference sequence database. However, no further information is available for these homo-logues. Using whole-mount in situ hybridization, mouse scirr1 mRNA was expressed temporally and spatially in accordance with the early development sequence of the central nervous system. In adult rat spinal cord, expression of scirr1 mRNA was localized to neurons of gray matter by in situ hybridization. Using immunohistochemistry, SCIRR1 protein was found to be up-regulated and expressed more highly in spinal cord neurons farther from the epicenter of injury. Although the precise function of SCIRR1 is unknown, its unique pattern of expression during CNS early development and up-regulation after spinal cord injury sugges t that SCIRR1 should be involved in the succeeding injury and/or repair processes of the injured spinal cord. Also, the typical F-box and leucine-rich repeat (LRR) architecture of substrate recruiting role in the pleiotropic ubiquitin/ proteasome pathway. All these make scirr1 a new interesting start to study the spinal cord injury and regeneration mechanism.
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