정상 성인에서 총콜레스테롤의 분별치와 관련 요인 : 전북지역 한 종합병원의 정기검진자를 중심으로

김지식,여영규,홍인선 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 1996 Journal of biomedical laboratory sciences Vol.2 No.2

정상 성인에서 혈청 총 콜레스테롤의 분별치 및 관련된 제요인을 파악하기 위하여 1995년 3월부터 10월까지 8개월 동안 전주 예수병원에서 의료보험 피보험자와 피부양자를 대상으로한 정기 건강 검진을 받은 대상자 중 성별, 연령별, 혈압, 체중, 기타 생화학적 검사 결과를 분석하였으며, 이들 중 고혈압 등 질병이 없는 건강한 집단으로 1,818명을 분석하였다. 혈청 총 콜레스테롤의 분별치를 산정 하기 위한 75th percentile값을 보면, 21∼30세군에 191 mg/dl, 31∼40군에서 195 mg/dl, 41∼50세군에서 214 mg/dl, 51∼60세군에서 227 mg/dl, 그리고 61세 이상 군에서 222 mg/dl이었다. 90th percentile값을 보면, 21∼30세군에서 214 mg/dl, 31∼40군에서 214 mg/dl, 41∼50세군에서 239 mg/dl, 51∼60세군에서 253mg/dl, 그리고 61세 이상군에서 248 mg/dl 이었다. 혈청 총 콜레스테롤과 각 변수간의 상관관계는 연령과는 남.여 모두 유의한 관계를 보였고(p<0.001), 특히 여자에서 높은 상관성을 보였다. 비만지수인 PIBW, BMI와도 유의한 상관성을 보였고, 수축기혈압과 이완기혈압과도 관련성을 보였다. 대상자들의 흡연 여부와 혈청 총 콜레스테롤과의 관계는 흡연군이 191.6±35.0 mg/dl 이었고, 비흡연군이 194.9±35.9 mg/dl였으며 두 집단간에는 유의한 차이를 보이지 않았다. 음주에 따른 혈청 총 콜레스테롤의 측정치는 비음주군에서는 196.0±36.0 mg/dl 이었고, 음주군에서는 188.9±34.5 mg/dl로 두 군간에는 유의한 차이를 보였다. 운동 습관과 혈청 총 콜레스테롤의 관계는 규칙적으로 운동을 하는 군은 192.1±33.3 mg/dl이었고, 운동을 하지 않는 군은 195.8±37.0 mg/dl였으며 두 군간에는 유의한 차이를 보였다. The cut-off values and related factors for total cholesterol of serum in normal Korean adults were studied from March to October, 1995, based on the data of 1,818 healthy adults of human involved the male and female. The comparisons of the serum total cholesterol levels were analyzed by sex, age, systolic blood pressure, diastolic blood pressure, body weight, height, PIBW, BMI and other biochemical tests. 1. The serum total cholesterol level were 194.4 mg/dl in total group, 186.9 mg/dl for male, and 197.6 mg/dl for female. 2. There was no significant differences by sex among the 21 to 50 ages group, but significantly higher in women than in men over 51 years old. 3. In general, the levels of serum total cholesterol were increased with age, the highest level in men was 192.7 mg/dl in 51 to 60 years old, and 210.5 mg/dl in more than 60 years old in women. 4. The cut-off values of serum total cholesterol for moderate risk were 191 mg/dl in 21 to 30 years group, 195 mg/dl in 31 to 40 years, 214 mg/dl in 41 to 50 years, 227 mg/dl in 51 to 60 years, and 222 mg/dl in more than 61 years. The cut-off values of serum total cholesterol for high risk were 214 mg/dl in 21 to 30 years group, 214 mg/dl in 31 to 40 years, 239 mg/dl in 41 to 50 years, 253 mg/dl in 51 to 60 years, and 248 mg/dl in more than 61 years. 5. The mean values of serum total cholesterol were showed positive correlation with age, PIBW, BMI, systolic blood pressure and diastolic blood pressure. 6. Serum total cholesterol level of drinking group(188.9±34.5mg/dl) was showed lower than those of non-drinking group(196.0±36.0mg/dl). 7. Serum total cholesterol levels of regular excercise group(192. 1±33.3 mg/dl) was significantly lower than those of non regular excercise group(195.8± 37.0 mg/dl).

대학의 홍보가 대학 이미지 및 경쟁력 지각에 미치는 영향에 관한 연구 : 2년제 대학의 홍보전략을 중심으로

정형식,김영심,김영인 朝鮮大學校 2002 經營經濟硏究 = Management and economics research Vol.25 No.1

셰익스피어 작품속의 우정에 대한 연구

추영식 조선대학교 인문학연구소 1998 外國文化硏究 Vol.21 No.1

Critical work on the subject of friendship in the plays of Shakespeare is limited. Clifford Leech and Muriel Bradbrook have discussed the relationship between Proteus and Valentine in The Two Gentlemen of Verona, and a handful of critics, have investigated the complex friendship of Leontes and Polixenes in Winter's Tale. But they attempted to evaluate Shakespeare's Treatment of friendship inside the context of the individual play. In this paper I'd like to attempt to treat friendship theme rather than heterosexual love even restricted to the genre of comedy and romance. I will try to demonstrate that the conflict in The Two Gentlemen of Verona is not between friendship and love as much as between submission and control. Valentine's love for Silvia, like that of Proteus for Julia, is much closer to Romeo's initial infatuation with Rosaline than his love for Juliet. The rivalry between the two friends has little to do with the love of a woman; it has everything to do with hurt pride, with the attempted of the adolescent to assert his identity and establish control.

The Old Man and the Sea에 나타난 克己의 意味

秋英植 조선대학교 인문학연구소 1983 外國文化硏究 Vol.6 No.1

본고에서는 Hemingway의 모든 작품에 빠지지 않고 등장하는 violent한 상황의 연유를 그가 체험한 실재사실의 관점에서 살펴보고 The Old Man and the Sea의 Santiago 노인이 보여주는 우애와 범애정신 그리고 극기의 의미를 고찰하고자 한다.

학습제어기를 이용한 다이렉트 드라이브 매니퓰레이터의 위치제어에 관한 연구

안영주,신춘식,황용연 釜慶大學校 1996 釜慶大學校 論文集 Vol.1 No.2

Direct drive robots are suitable to the position and force control with high accuracy, but it is difficult to design a controller because of the system's nonlinearity and link-interactions. This paper is concerned with the study of the position control of direct drive robots. The proposed algorithm consists of a feedback controller and neural networks. After the completion of learning, the output of the feedback controller is nearly equal to zero, and the neural networks play an important role in the control system. Therefore, the optimum setting of control parameters is unnecessary. In other words, the proposed algorithm does not need any knowledge of the controlled system in advance. The effectiveness of the proposed algorithm is demonstrated by the experiment on the position control of the parallelogram link-type direct drive robot.

새조개 가공부산물을 이용한 속성 액젓의 제조 및 저장안정성

김명희,조영철,배태진,손정호,김귀식 여수대학교 1997 論文集 Vol.11 No.2

A rapid processing for fermented fish sauce from cockle shell by-product and their quality and storage stability was investigated. The weight ratio of cockle shell by-product about the whole cockle shell was 32.7%, and contents of moisture, portein, lipid, carbohydrate and ash were 83.1%, 10.7%, 2.4%, 1.0% and 2.9%, respetively. The cockle shell by-product was homogenized with addition of water and hydrolyzed at 50℃ for 8 hours added 4% Protease N.P.(3.14ㆍ10⁴U/g). The hydrolysate was thermally treated at 100℃ for 60 minutes with 4% invert sugar and 20% table salt was finally added to the product. The chemical compositon of moisture, carbohydrate, ash, salinity, total nitrogen and amino type nitrogen of fermented sauce from cockle shell by-product were 65.4%, 3.9%, 20.8%, 18.9%, 1,683 mg% and 1,426 mg%, respectively. The major nucleotides and their relative compounds in the product were AMP and hypoxanthine and their contents were 3.36μ mole/g and 1.95μ mole/g. And major free amino acid were glutamic acid, lysine, leucine, valine and aspatic acid.

백서에서 치아이동 후 보정기간 동안 교합이 치주조직섬유의 재형성에 미치는 영향

정권희,박영준,이기헌,황현식 대한치과교정학회 2003 대한치과교정학회지 Vol.33 No.2

본 연구는 실험적 치아이동 후 보정기간 동안 교합이 치주조직섬유의 물리적 강도에 미치는 영향을 알아보고자 시행되었다. 체중 200g 내외의 Sprague-Dawley계 백서 수컷에서 상악 양측 제1대구치와 2대구치 사이에 교정용 고무줄을 삽입하여 4일 동안 치아를 이동시킨 다음, 각 실험동물의 하악 좌측 베1, 2, 3대구치를 발치하여 우측은 대합치가 있는 교합측으로, 좌측은 비교합측으로 구분하였다. 상악 제1대구치와 2대구치 사이의 인접면에 유지구를 형성하고 광중합형 레진으로 채워 보정을 시행한 후 시작 0일, 4일, 8일, 12일, 16일 또는 20일 경과한 후 백서를 희생시킨 다음, 만능물성 시험기를 이용하여 상악 제1대구치를 발치할 때 필요한 최대인장강도를 측정 좌우간 비교 분석하여 다음과 같은 결과를 얻었다. 1. 교합측은 비보정군에서 보정 4일, 8일, 12일, 16일, 20일군으로 갈수록 최대인장강도사 증가하였고, 보정 12일군 이후부터 통계적으로 유의한 차이를 보였다(p<0.05). 2. 비교합측은 비보정군에서 4일, 8일, 12일, 16일, 20일군으로 갈수록 최대인장강도가 증가하는 경향을 보였으나 통계적으로 유의한 차이를 보이지 않았다(p<0.05) 3. 교합측과 비교합측의 최대인장강도를 비교한 결과 보정 8일군까지 통계적으로 유의한 차이를 보이지 않았으나 (p>0.05), 보정 12일군 이후 보정 20일군까지 통계적으로 유의한 차이를 보였다(p<0.05). 이상의 결과는 실험적 치아이동 후 보정기간 동안 교합이 치주조직 섬유의 재형성에 영향을 미침으로 보정장치의 선택, 기간설정 등 보정계획서 교합에 대한 고려가 필요함을 시사하였다. The purpose of this study was to valuate the effect of occlusion on the mechanical strength of periodontal fibers during retention periods after experimental tooth movement. In the Sprague-Dawley male rats weighing 200g or more, the intraoral elastics were inserted into the both right and left interproximal space between upper first and second molars for tooth movement. After 4 days later, the left lower first, second, and third molars were extracted for differentiating the non-occlusal side from the occlusal side in the same mouth. At the same time the elastics were removes and than light cured resin was placed in the space between upper first and second molard following undercut was made for retention bilaterally. From the beginning of retention, 7 rats were sacrificed at 0, 4, 8, 12, 16, 20 days respectively. For evaluating of magnitude on the mechanical strength of periodontal tissue, the maximal shear load of the upper first molars were measured bilaterally during extraction using Instron Universal Testing Machine. The results of this study were obtained as follows : 1. In the occlusal side, the maximal shear load was increased from no retention to retention 20 days group as time was going and statistically difference was shown from retention 12 days group (p<0.05). 2. In the non-occlusal side, the maximal shear load was increased slightly from no retention 20 days group as time was going but there was no statistically difference (p>0.05) 3. The result compared with the maximal shear load between occlusal and nonocclusal side showed no statistically difference until retention 8 day group (p>0.05), but showed statistically difference from retention 12 day to 20 day group (p<0.05). These results show that occlusion had an effect on mechanical strength of the periodontal fibers during retention periods after experimental tooth movement; therefore, it is suggested that occlusion should be considered while the retainer types and retention period are planned.

Heparin : Structure and Aniticoagulant Activity

Yeong Shik Kim 생화학분자생물학회 1990 90년도 학술대회 초록 Vol.- No.-

ANALYSIS OF GLYCOPROTEIN AND POLYSACCHARIDE USING FLUORESCENCELABLED CONJUGATES WITH HPLC AND ELECTROPHORESIS

Yeong Shik Kim,Kyung Shin Park,Bum Soo Han 생화학분자생물학회 1993 생화학분자생물학회 춘계학술발표논문집 Vol.- No.-

Glycosaminoglycan lyases and acharan sulfate

Yeong Shik Kim 한국당과학회 2009 한국당과학회 학술대회 Vol.2009 No.1

Glycosaminoglycans (GAGs) are unbranched, polydisperse, acidic polysaccharides, often covalently linked to a protein core to form proteoglycans (PGs). The most common GAGs are heparin, heparan sulfate (HS), hyaluronic acid (HA), chondroitin sulfate (CS), dermatan sulfate (DS), and keratan sulfate (KS). Heparin, an anticoagulant isolated from animal tissue, is an important and chemically unique polysaccharide of considerable biological significance. In order to understand the complicated structure of GAGs, GAG lyases from microorganisms have been widely used and their reaction products were analyzed using various HPLC methods. We have cloned and expressed GAG lyases of Bacteroides thetaitaomicron in E.coli. In collaboration with Dr Mirek Cygler’s group, the tertiary structures of recombinant chondroitinases ABC and heparinase have been solved. These things will be presented. Acharan sulfate (AS), isolated from the giant African snail Achatina fulica, primarily consists of the repeating disaccharide structure a-D-N-acetylglucosaminyl (1→4) 2-sulfoiduronic acid. Its structure is related to heparin and heparan sulfate but is distinctly different from all known members of these classes of glycosaminoglycans. Because of its structural similarities to heparin, a diverse array of biological activities and functions have been studied. Because of its high molecular weight and copper binding affinity, specific proteins in the plasma could be purified by affinity chromatography.