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Tumor DNA Content Analysis by Flow Cytometry
Wittwer.Carl T 啓明大學校 醫科大學 1989 계명의대학술지 Vol.8 No.2
DNA Content flow cytometry is a useful diagnostic and prognostic tool(1,2). Both proliferative activity (cell cycle analysis) and the presence of abnormal amounts of DNA(DNA content aneuploidy) often correlate with tumor stage, histolotic grade, and prognosis(3,4).
Wind tunnel study of plume dispersion with varying source emission configurations
Adrián R. Wittwer,Acir M. Loredo-Souza,Edith B. Camaño Schettini,Hugo G. Castro 한국풍공학회 2018 Wind and Structures, An International Journal (WAS Vol.27 No.6
The concentration fields in the proximities of a local gas emission source are experimentally analyzed in several combinations of wind incidences and source emissions. These conditions are determined by the plume buoyancy, emission velocity and incident flow wind speed. Concentration measurements are performed by an aspirating probe in a boundary layer wind tunnel. The analysis included the mean concentration values and the intensity of concentration fluctuations in a neutral atmospheric boundary layer flow. Different configurations are tested: an isolated stack in a homogeneous terrain and a stack with a bluff body in close proximity, located windward and leeward from the emission source. The experimental mean concentration values are contrasted with Gaussian profiles and the dilution factor is analyzed with respect to the empirical curves of the minimum dilution. Finally, a study on the plume intermittency is performed in a cross-sectional plane near the emission source. It is possible to highlight the following observations: a) plume vertical asymmetry in the case of an isolated emission source, b) significant differences in the dispersion process related to the relative location of the emission source and bluff body effects, and c) different probabilistic behavior of the concentration fluctuation data in a cross-sectional measurement plane inside the plume.
Characteristics of Zonda wind in South American Andes
Loredo-Souza, Acir M.,Wittwer, Adrian R.,Castro, Hugo G.,Vallis, Matthew B. Techno-Press 2017 Wind and Structures, An International Journal (WAS Vol.24 No.6
This paper discusses some features and conditions that characterize the Zonda wind, focusing particularly on the implications for wind engineering applications. This kind of wind, typical of mountainous regions, is far from being adequately characterized for computational simulations and proper modeling in experimental facilities such as boundary layer wind tunnels. The objective of this article is to report the research works that are being developed on this kind of wind, describing the main obtained results, and also to establish some general guidelines for the proper analysis of the Zonda in the wind engineering context. A classification for the Zonda wind is indicated and different cases of structural and environmental effects are described. Available meteorological data is analyzed from the wind engineering point of view to obtain the Zonda wind gust factors, as well as basic wind speeds relevant for structural design. Some considerations and possible directions for the Zonda wind-tunnel and computational modeling are provided. Gust factor values larger than those used for open terrain were obtained, nevertheless, the basic wind speed values obtained are similar to values presented by the Argentinian Wind Code for three-second gust, principally at Mendoza airport.
Noncontact techniques for monitoring of tunnel linings
White, Joshua,Hurlebaus, Stefan,Shokouhi, Parisa,Wittwer, Andreas,Wimsatt, Andrew Techno-Press 2014 Structural monitoring and maintenance Vol.1 No.2
An investigation of tunnel linings is performed at two tunnels in the US using complimentary noncontact techniques: air-coupled ground penetrating radar (GPR), and a vehicle-mounted scanning system (SPACETEC) that combines laser, visual, and infrared thermography scanning methods. This paper shows that a combination of such techniques can maximize inspection coverage in a comprehensive and efficient manner. Since ground-truth is typically not available in public tunnel field evaluations, the noncontact techniques used are compared with two reliable in-depth contact nondestructive testing methods: ground-coupled GPR and ultrasonic tomography. The noncontact techniques are used to identify and locate the reinforcement mesh, structural steel ribs, internal layer interfaces, shallow delamination, and tile debonding. It is shown that this combination of methods can be used synergistically to provide tunnel owners with a comprehensive and efficient approach for monitoring tunnel lining conditions.
Characteristics of Zonda wind in South American Andes
Acir M. Loredo-Souza,Adrian R. Wittwer,Hugo G. Castro,Matthew B.Vallis 한국풍공학회 2017 Wind and Structures, An International Journal (WAS Vol.24 No.6
This paper discusses some features and conditions that characterize the Zonda wind, focusing particularly on the implications for wind engineering applications. This kind of wind, typical of mountainous regions, is far from being adequately characterized for computational simulations and proper modeling in experimental facilities such as boundary layer wind tunnels. The objective of this article is to report the research works that are being developed on this kind of wind, describing the main obtained results, and also to establish some general guidelines for the proper analysis of the Zonda in the wind engineering context. A classification for the Zonda wind is indicated and different cases of structural and environmental effects are described. Available meteorological data is analyzed from the wind engineering point of view to obtain the Zonda wind gust factors, as well as basic wind speeds relevant for structural design. Some considerations and possible directions for the Zonda wind-tunnel and computational modeling are provided. Gust factor values larger than those used for open terrain were obtained, nevertheless, the basic wind speed values obtained are similar to values presented by the Argentinian Wind Code for three-second gust, principally at Mendoza airport.