Anterior capsular reconstruction with acellular dermal allograft for subscapularis deficiency: a report of two cases

Raffy Mirzayan,Shane Korber 대한견주관절학회 2024 대한견주관절의학회지 Vol.27 No.1

Anterior glenohumeral instability with an irreparable subscapularis tear is a challenging problem for the orthopedic shoulder surgeon. Current techniques, including tendon transfers, yield inconsistent results with high rates of recurrent instability. Acellular dermal allografting has been used in young patients with massive superior rotator cuff tears with early success, but acellular dermal allografting is comparatively unstudied in anterior deficiency. We present two cases of anterior capsular reconstruction with an acellular dermal allograft in patients ages 66 and 58 years with irreparable subscapularis tendon tears. Follow-up for both patients exceeded 4 years, with forward flexion >140°, external rotation exceeding 60°, a Single Assessment Numeric Evaluation score >90 points, a visual analog scale score of 0 points, and an American Shoulder and Elbow Score of 98 points. In conclusion, acellular dermal allografting can be used to reconstruct the anterior capsule in patients with massive irreparable subscapularis tears, similar to its use in superior capsular reconstruction in patients with massive posterosuperior rotator cuff tears.

Synthesis of Ag-Loaded TiO2 Electrospun Nanofibers for Photocatalytic Decolorization of Methylene Blue

M. Raffi,Zaira Batool,Mashkoor Ahmad,M. Zakria,Rana I. Shakoor,Muhammad Aslam Mirza,Arshad Mahmood 한국섬유공학회 2018 Fibers and polymers Vol.19 No.9

Titanium dioxide (TiO2) is one of the excellent photocatalysts used for degradation of environmetal pollutants. In this work, 2.5, 5.0 and 7.5 wt.% of silver (Ag)-loaded TiO2 nanofibers of mean size 52-134 nm were synthesized by electrospinning method. These electrospun nanofibers were calcined at 500 oC to enable the transformation of Rutile (R) phase to Anatase (A), elimination of reaction moieties from the TiO2 matrix and subsequently formation of Ag clusters. The effect of Ag loading on the morphology, crystal structure, phase transformation, and band gap of these electrospun nanofibers have been characterized by scannining electron microscopy (SEM), X-ray diffraction (XRD), fourier transform infrared spectroscopy (FTIR), raman spectroscopy and UV-visible spectroscopy. These nanofibers exhibited a red-shift in the absorbance edge and a significant enhancement of light absorption in the wavelength range of 250-550 nm. These electrospun nanofibers were investigated for photodecomposition of methylene blue (MB), and photocatalytic decolorization rates were determined by pseudo-first-order equation. The rate constants for the pure and those of 2.5, 5.0, and 7.5 wt% Agloaded TiO2 nanofibers were computed to be 0.1439 min-1, 0.1608 min-1, 0.1876 min-1, and 0.2251 min-1 respectively.

Soil Chemical Properties of Selected two Herbs Intercropped With Paraserianthes Falcataria at Degraded Forest Area in Tangkulap Forest Reserve, Telupid, Sabah

Affendy Hassan,Normah Awang Besar Raffie,Azmy Mohamed 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Reinforcement of Electromagnetic Wave Absorption Characteristics in PVDF‑PMMA Nanocomposite by Intercalation of Carbon Nanofibers

Anam Naseer,Muhammad Mumtaz,Muhammad Raffi,Izhar Ahmad,Sabih D. Khan,Rana I. Shakoor,Shaista Shahzada 대한금속·재료학회 2019 ELECTRONIC MATERIALS LETTERS Vol.15 No.2

With the recent developments in the millimeter and sub-millimeter wave instruments and devices, there is a need to developelectromagnetic (EM) wave absorbing materials in these frequency bands for applications like electromagnetic interferencecontrol, electromagnetic compatibility, etc. In this work, carbon nanofi bers (CNF) were uniformly dispersed in a blend ofpoly(methyl methacrylate), polyvinylidene fl uoride and cyanoacrylate for air spray coating a fi lm on the cellulosic substrates. The samples were characterized for evaluation of their structure, morphology, electrical and EM absorption properties in0.15–1.2 THz range by X-ray diff raction, fi eld emission electron microscopy, I–V measurements and terahertz time domainspectroscopy. These coatings can conveniently be applied to the material surfaces by conventional air spray painting method,which makes this technique cost-eff ective as well as easy to deploy in various applications. The electrical conductivityenhancement in the samples has been attributed to the formation of conducting network by uniform distribution of CNFs inthe insulating polymer matrix. As a result, the shielding eff ectiveness (SE) has been observed to improve with the increasein CNF’s loading in the polymer matrix. The SE is also a function of frequency, which is attributed to the increase in theskin depth. A SE of 20 dB has been estimated in these samples for the frequencies 1 THz and higher, which is of signifi cantimportance for the use of this technique in practical applications.

A Cenozoic record of the equatorial Pacific carbonate compensation depth

P채like, Heiko,Lyle, Mitchell W.,Nishi, Hiroshi,Raffi, Isabella,Ridgwell, Andy,Gamage, Kusali,Klaus, Adam,Acton, Gary,Anderson, Louise,Backman, Jan,Baldauf, Jack,Beltran, Catherine,Bohaty, Steven M.,Bo Nature Publishing Group, a division of Macmillan P 2012 Nature Vol.488 No.7413

Atmospheric carbon dioxide concentrations and climate are regulated on geological timescales by the balance between carbon input from volcanic and metamorphic outgassing and its removal by weathering feedbacks; these feedbacks involve the erosion of silicate rocks and organic-carbon-bearing rocks. The integrated effect of these processes is reflected in the calcium carbonate compensation depth, which is the oceanic depth at which calcium carbonate is dissolved. Here we present a carbonate accumulation record that covers the past 53 million years from a depth transect in the equatorial Pacific Ocean. The carbonate compensation depth tracks long-term ocean cooling, deepening from 3.0??3.5??kilometres during the early Cenozoic (approximately 55??million years ago) to 4.6 kilometres at present, consistent with an overall Cenozoic increase in weathering. We find large superimposed fluctuations in carbonate compensation depth during the middle and late Eocene. Using Earth system models, we identify changes in weathering and the mode of organic-carbon delivery as two key processes to explain these large-scale Eocene fluctuations of the carbonate compensation depth.

Probing of Potential Luminous Bacteria in Bay of Bengal and Its Enzyme Characterization

( Senthil S Balan ),( S M Raffi ),( S Jayalakshmi ) 한국미생물 · 생명공학회 2013 Journal of microbiology and biotechnology Vol.23 No.6

The present study dealt with the isolation, identification and enzyme characterization of potential luminous bacteria from water, sediment, squid, and cuttle fish samples of the Karaikal coast, Bay of Bengal, India during the study period September 2007 - August 2008. Bioluminescent strains were screened in SWC agar and identified using bi℃hemical tests. As Shewanella henadai was found to be the most common and abundant species with maximum light emission [69,702,240 photons per second (pps)], the optimum ranges of various physic℃hemical parameters that enhance the luciferase activity in Shewanella hanedai were worked out. The maximum luciferase activity was observed at the temperature of 25℃ (69,674,387 pps), pH of 8.0 (70,523,671 pps), salinity of 20 ppt (71,674,387 pps), incubation period of 16 h (69,895,714 pps), 4% peptone (70,895,152 pps) as nitrogen source, 0.9% glycerol (71,625,196 pps), and the ionic supplements of 0.3% CaCO3 (73,991,591 pps), 0.3% K2HPO4 (73,919,915 pps), and 0.2% MgSO4 (72,161,155 pps). Shewanella hanedai was cultured at optimum ranges for luciferase enzyme characterization. From the centrifuged supernatant, the proteins were precipitated with 60% ammonium sulfate, dialyzed, and purified using anionexchange chromatography, and then luciferase was eluted with 500 mM phosphate of pH 7.0. The purified luciferase enzyme was subjected to SDS-PAGE and the molecular mass was determined as 78 kDa.

Safety Evaluation of LB10522,a New Cephalosporin Antibiotic

Lee, Chang ho,Kim, Seong Il,Kwak, Jin Hwan,Mikaelian, Raffi,Kim, In Chull 한국응용약물학회 1995 Biomolecules & Therapeutics(구 응용약물학회지) Vol.3 No.4

All the pharmacological studies of LB10522 described here were carried out with high doses (fifteen to sixty times of the therapeutic dose) to determine an indication of potential side effects in clinical use in terms of the acute clinical signs, cardiovascular and central nervous system. LB10522 does not produce any observable clinical signs except for the symptoms such as moist eye, skin rash, slight salivation, vomitting, and slightly reduced activity. The effects of LB10522 on the hemodynamics and cardiac function of anesthetized beagle dogs are as follows; heart rates and mean arterial blood pressure had a tendency to increase mildly, which is a normal finding in anesthetized dogs. All the animals except for one showed relatively stable respiratory rates throughout the observation period. Each animal treated with LB10522 showed slight increase in the left cardiac work and left ventricular stroke work which are mainly related to corresponding increases in cardiac output. Femoral blood flow were shown to be increased in some animals treated with LB10522. The epileptogenic activities of various cephalosporins were assessed by a direct intracerebral injection of appropriate concentration of test articles. The CD_(50) values (nmol) obtained from the analysis of the dose-response data are as follows; 78.2, 175.3, 156.3, and 53.5 for cefazolin, cephaloridine, ceftazidime, and LB 10522, respectively. LB10522 seems to be equipotent with cefazolin or to be three times more potent than cephaloridine and ceftazidime in causing adverse CNS stimulation. Taken into consideration all the information obtained, LB10522 is not supposed to induce much changes in the functions examined in these studies in man at therapeutic doses.

3D field phase-space control in tokamak plasmas

Park, Jong-Kyu,Jeon, YoungMu,In, Yongkyoon,Ahn, Joon-Wook,Nazikian, Raffi,Park, Gunyoung,Kim, Jaehyun,Lee, HyungHo,Ko, WonHa,Kim, Hyun-Seok,Logan, Nikolas C.,Wang, Zhirui,Feibush, Eliot A.,Menard, Jon NATURE PUBLISHING GROUP 2018 NATURE PHYSICS Vol.14 No.12

Functional characterization of a T-DNA inserted STN8 kinase mutant of Rice

Krishna Nath,Sujata R Mishra,Ismayil S Zulfugarov,Sharif Ar Raffi,Gynheung An,Choon Hwan Lee 한국육종학회 2007 한국육종학회 학술발표회 발표요지 Vol.39 No.-

The Clinical Impact of Advanced Age on the Postoperative Outcomes of Patients Undergoing Gastrectomy for Gastric Cancer: Analysis Across US Hospitals Between 2011–2017

Lee David Uihwan,Fan Gregory Hongyuan,Chang Kevin,Lee Ki Jung,Han John,Jung Daniel,Kwon Jean,Karagozian Raffi 대한위암학회 2022 Journal of gastric cancer Vol.22 No.3

Purpose This study systematically evaluated the implications of advanced age on post-surgical outcomes following gastrectomy for gastric cancer using a national database. Materials and Methods The 2011–2017 National Inpatient Sample was used to isolate patients who underwent gastrectomy for gastric cancer. From this, the population was stratified into those belonging to the younger age cohort (18–59 years), sexagenarians, septuagenarians, and octogenarians. The younger cohort and each advanced age category were compared in terms of the following endpoints: mortality following surgery, length of hospital stay, charges, and surgical complications. Results This study included a total of 5,213 patients: 1,366 sexagenarians, 1,490 septuagenarians, 743 octogenarians, and 1,614 under 60 years of age. Between the younger cohort and sexagenarians, there was no difference in mortality (2.27 vs. 1.67%; P=0.30; odds ratio [OR], 1.36; 95% confidence interval [CI], 0.81–2.30), length of stay (11.0 vs. 11.1 days; P=0.86), or charges ($123,557 vs. $124,425; P=0.79). Compared to the younger cohort, septuagenarians had higher rates of in-hospital mortality (4.30% vs. 1.67%; P<0.01; OR, 2.64; 95% CI, 1.67–4.16), length of stay (12.1 vs. 11.1 days; P<0.01), and charges ($139,200 vs. $124,425; P<0.01). In the multivariate analysis, septuagenarians had higher mortality (P=0.01; adjusted odds ratio [aOR], 2.01; 95% CI, 1.18–3.43). Similarly, compared to the younger cohort, octogenarians had a higher rate of mortality (7.67% vs. 1.67%; P<0.001; OR, 4.88; 95% CI, 3.06–7.79), length of stay (12.3 vs. 11.1 days; P<0.01), and charges ($131,330 vs. $124,425; P<0.01). In the multivariate analysis, octogenarians had higher mortality (P<0.001; aOR, 4.03; 95% CI, 2.28–7.11). Purpose This study systematically evaluated the implications of advanced age on post-surgical outcomes following gastrectomy for gastric cancer using a national database. Materials and Methods The 2011–2017 National Inpatient Sample was used to isolate patients who underwent gastrectomy for gastric cancer. From this, the population was stratified into those belonging to the younger age cohort (18–59 years), sexagenarians, septuagenarians, and octogenarians. The younger cohort and each advanced age category were compared in terms of the following endpoints: mortality following surgery, length of hospital stay, charges, and surgical complications. Results This study included a total of 5,213 patients: 1,366 sexagenarians, 1,490 septuagenarians, 743 octogenarians, and 1,614 under 60 years of age. Between the younger cohort and sexagenarians, there was no difference in mortality (2.27 vs. 1.67%; P=0.30; odds ratio [OR], 1.36; 95% confidence interval [CI], 0.81–2.30), length of stay (11.0 vs. 11.1 days; P=0.86), or charges ($123,557 vs. $124,425; P=0.79). Compared to the younger cohort, septuagenarians had higher rates of in-hospital mortality (4.30% vs. 1.67%; P<0.01; OR, 2.64; 95% CI, 1.67–4.16), length of stay (12.1 vs. 11.1 days; P<0.01), and charges ($139,200 vs. $124,425; P<0.01). In the multivariate analysis, septuagenarians had higher mortality (P=0.01; adjusted odds ratio [aOR], 2.01; 95% CI, 1.18–3.43). Similarly, compared to the younger cohort, octogenarians had a higher rate of mortality (7.67% vs. 1.67%; P<0.001; OR, 4.88; 95% CI, 3.06–7.79), length of stay (12.3 vs. 11.1 days; P<0.01), and charges ($131,330 vs. $124,425; P<0.01). In the multivariate analysis, octogenarians had higher mortality (P<0.001; aOR, 4.03; 95% CI, 2.28–7.11).