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Optical Technique to Measure Five-Degree-of-Freedom Error Motions for a High-Speed Microspindle
Hiroshi Murakami1,Norio Kawagoishi,Eiji Kondo,Akira Kodama 한국정밀공학회 2010 International Journal of Precision Engineering and Vol. No.
We present an optical technique to measure five-degree-of-freedom error motions of a high-speed microspindle. The measurement system consists of a rod lens, a ball lens, four divided laser beams, and multiple divided photodiodes. When the spindle rotates with its concomitant rotation errors, the rod and ball lenses, which are mounted to the chuck of the spindle, are displaced, and this displacement is measured using an optical technique. For this study, we decide the design parameters of the optical system using ray tracing, fabricate a prototype of the measurement system, and evaluate it experimentally. The results show that the measurement system has a resolution of 5 nm and can be used to evaluate high-speed microspindle rotation errors.
Setting the scene: CFD and symposium overview
Murakami, Shuzo Techno-Press 2002 Wind and Structures, An International Journal (WAS Vol.5 No.2
The present situation of CWE(Computational Wind Engineering) and the papers presented to the CWE 2000 Symposium are reviewed from the following viewpoints; 1) topics treated, 2) utilization of commercial code (software), 3) incompleteness of CWE, 4) remaining research subjects, 5) prediction accuracy, 6) new fields of CWE application, etc. Firstly, new tendencies within CWE applications are indicated. Next, the over-attention being given to the application field and the lack of attention to fundamental problems, including prediction error analysis, are pointed out. Lastly, the future trends of CFD (Computational Fluid Dynamics) applications to wind engineering design are discussed.
Murakami, Katsuhisa,Rommel, Mathias,Hudec, Boris,Rosová,, Alica,Huš,eková,, Kristí,na,Dobroč,ka, Edmund,Rammula, Raul,Kasikov, Aarne,Han, Jeong Hwan,Lee, Woongkyu,Song, S American Chemical Society 2014 ACS APPLIED MATERIALS & INTERFACES Vol.6 No.4
<P>Topography and leakage current maps of TiO<SUB>2</SUB> films grown by atomic layer deposition on RuO<SUB>2</SUB> electrodes using either a TiCl<SUB>4</SUB> or a Ti(O-i-C<SUB>3</SUB>H<SUB>7</SUB>)<SUB>4</SUB> precursor were characterized at nanoscale by conductive atomic force microscopy (CAFM). For both films, the leakage current flows mainly through elevated grains and not along grain boundaries. The overall CAFM leakage current is larger and more localized for the TiCl<SUB>4</SUB>-based films (0.63 nm capacitance equivalent oxide thickness, CET) compared to the Ti(O-i-C<SUB>3</SUB>H<SUB>7</SUB>)<SUB>4</SUB>-based films (0.68 nm CET). Both films have a physical thickness of ∼20 nm. The nanoscale leakage currents are consistent with macroscopic leakage currents from capacitor structures and are correlated with grain characteristics observed by topography maps and transmission electron microscopy as well as with X-ray diffraction.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2014/aamick.2014.6.issue-4/am4049139/production/images/medium/am-2013-049139_0008.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am4049139'>ACS Electronic Supporting Info</A></P>
Murakami, Haruyasu,Nokihara, Hiroshi,Hayashi, Hidetoshi,Seto, Takashi,Park, Keunchil,Azuma, Koichi,Tsai, Chun‐,Ming,Yang, James Chih‐,Hsin,Nishio, Makoto,Kim, Sang‐,We,Kiura, Katsuyu John Wiley and Sons Inc. 2018 CANCER SCIENCE Vol.109 No.9
<P>Epidermal growth factor receptor (EGFR)‐activating mutations confer sensitivity to tyrosine kinase inhibitor (TKI) treatment for non‐small‐cell lung cancer (NSCLC). ASP8273 is a highly specific, irreversible, once‐daily, oral, EGFR TKI that inhibits both activating and resistance mutations. This ASP8273 dose‐escalation/dose‐expansion study (NCT02192697) was undertaken in two phases. In phase I, Japanese patients (aged ≥20 years) with NSCLC previously treated with ≥1 EGFR TKI received escalating ASP8273 doses (25‐600 mg) to assess safety/tolerability and to determine the maximum tolerated dose (MTD) and/or the recommended phase II dose (RP2D) by the Bayesian Continual Reassessment Method. In phase II, adult patients with T790M‐positive NSCLC in Japan, Korea, and Taiwan received ASP8273 at RP2D to further assess safety/tolerability and determine antitumor activity, which was evaluated according to Simon's two‐stage design (threshold response = 30%, expected response = 50%, α = 0.05, β = 0.1). Overall, 121 (n = 45 [33W/12M] phase I, n = 76 [48W/28M]) phase 2) patients received ≥1 dose of ASP8273. In phase I, RP2D and MTD were established as 300 and 400 mg, respectively. As 27 of the 63 patients treated with ASP8273 300 mg achieved a clinical response, ASP8273 was determined to have antitumor activity. The overall response rate at week 24 in all patients was 42% (n = 32/76; 95% confidence interval, 30.9‐54.0). Median duration of progression‐free survival was 8.1 months (95% confidence interval, 5.6, upper bound not reached). The most commonly reported treatment‐related adverse event in phase II was diarrhea (57%, n = 43/76). ASP8273 300 mg was generally well tolerated and showed antitumor activity in Asian patients with both EGFR‐activating and T790M mutations.</P>
Near Net Shape Processing of RE-Ba-Cu-O Bulk Superconductors
Murakami M.,Fujishiro M.,Miyazaki T.,Nariki S.,Sakai N.,Hirabayashi I. 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1
Several practical applications of melt-textured bulk superconductors require the complex-shaped products such as curved, ring-shaped, and drilled blocks rather than simple shaped pellets. However, melt-textured bulk superconductors are often damaged when they are cut, grinded, or drilled. With the aim of reducing such damages, we have investigated the preparation of the complex-shaped bulk superconductors by previously machining binder-added precursors and pre-sintered precursors. We could produce various complex-shaped bulk superconductors without cracking from these machined precursors
Murakami, Hideki 한국해운학회 2002 해운물류연구 Vol.36 No.-
This paper theoretically analyses the effects of an alliance by two small (dwarf) airlines on their own profit, their rival's profit, and the economic welfare. The rival is assumed to be a gigantic Gulliver. The Gulliver and the dwarves' profits will change in a different direction in the post-alliance situation. With regards to the social welfare, as long as the dwarf airline's alliance leads to the simultaneous achievement of strong economies of density, thorough product differentiation, seamlessness, and cost reduction, the social welfare would presumably be improved. The political implication is that firms' asymmetric factors (cost difference and product differentiation) should be maintained in the post alliance situation: otherwise, we cannot tell whether the dwarves' alliance will improve the social welfare or not.