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수정된 SCORM 표준을 적용한 목표지향 개인화 이러닝 시스템 설계 연구
이미정(Mijoung Lee),박종선(Jong-Sun Park),김기석(Kiseok Kim) 한국IT서비스학회 2008 한국IT서비스학회지 Vol.7 No.4
This paper suggests an e-learning system model, a goal-driven personalized e-learning system, which increase the effectiveness of learning. An e-learning system following this model makes the learner choose the learning goal. The learner’s choice would lead learning. Therefore, the system enables a personalized adaptive learning, which will raise the effectiveness of learning. Moreover, this paper proposes a SCORM standard, which modifies SCORM 2004 that has been insufficient to implement the “goal driven personalized e-learning system.” We add a data model representing the goal that motivates learning, and propose a standard for statistics on learning objects usage. We propose each standard for contents model and sequencing information model which are parts of “goal driven personalized e-learning system.” We also propose that manifest file should be added for the standard for contents model, and the file which represents the information of hierarchical structure and general learning paths should be added for the standard for sequencing information model. As a result, the system could sequence and search learning objects. We proposed an e-learning system and modified SCORM standards by considering the many factors of adaptive learning. We expect that the system enables us to optimally design personalized e-learning system.
Lee, Mijoung,Kim, Hyungha,Jeon, Deahyun,Hwang, Intaek,Choi, Bonghwan,Myung, Kyuho,Kim, Hyunggee,Choi, Yunjaie,Paik, Sanggi,Baik, Myunggi 충남대학교 생물공학연구소 1997 생물공학연구지 Vol.5 No.-
To understand molecular mechanisms of mammary gland involution, several clones were isolated after the primary differential screening of a total 40,000 pfu of involution-specific dDNA library, and further characterized. The partial sequences and Northern analysis revealed that iron metalbolism-related genes and mitochondrial genes were induced during mammary gland involution. The exrpession of the lactoferrin gene was induced at involution days 1, 2, and 3. The expression of ferritin heavy chain gene was induced at involution days 1, 2, 3 and 4. Cytochrome oxidase subunit 1 and cytochrome oxidase subunit 2 genes were induced at involution days 4 and 7. The expression of cytochrome b gene was induced at involution day 7. These results imply that iron metabolism and mitochondrial function may be altered during mammary gland involution. ⓒ 1996 Acdemic Press, Inc.
EGF Inhibits Expression of WDNM1 and Sulfated Glycoprotein-2 Genes in Mammary Epithelial Cells
Lee, Mijoung,Hwang, Intaek,Choi, Yunjaie,Paik, Sanggi,Lee, Hwanghee Blaise,Baik, Myunggi 충남대학교 생물공학연구소 1998 생물공학연구지 Vol.6 No.-
We have previously shown that expressions of ferritin heavy chain (FHC), WDNM1, and sulfated glycoprotein-2(SGP-2)genes are induced at an livolution stage of mammary gland. Here we studied the effect of lactogenic hormones and EGF on the expression of involution-induced genes in HC11 mammary epithelial cells. Insulin, dexamethasone, prolactin, and its combinations did not affect expression of the genes. When cells were cultured in growth medium containing EGF, expression of WDNM1 and SGP-2 genes was strongly inhibited in a dose- and time- dependent manner, whereas expression of FHC gene was not influenced by EGF. Results demonstrate that EGF inhibits expression of WDNM1 and SGP-2 genes in mammary epithelial cells. ⓒ 1997 Academic Press