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RISS 인기검색어
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- 저자 : Jun Hyung Moon(문준형) (검색결과 5 건)
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데모덱스 안검염 환자에서 폴리헥사메틸렌 비구아니드를 이용한 안검 세척의 치료효과
문준형,김재찬,Jun Hyung Moon,MD,Jae Chan Kim,MD,PhD 대한안과학회 2014 대한안과학회지 Vol.55 No.4
Purpose: To evaluate the treatment efficacy of polyhexamethylene biguanide (PHMB) lid scrub on Demodex blepharitis. Methods: Thirty-one patients diagnosed with Demodex blepharitis were evaluated every 2 weeks during 8 weeks of lid scrub treatment with 0.4% PHMB. Patients underwent epilation of 4 eyelashes in each eye, and the number of Demodex lesions was counted. The patients answered questionnaires regarding ocular surface discomfort and underwent ophthalmologic exams including slit lamp and tear breakup time (TBUT). Compliance was recorded as 1 of 3 stages (good, moderate, poor). Results: One patient was excluded for poor compliance. After PHMB lid scrub for 8 weeks, Demodex count was reduced in 28 of 30 patients (pre-PHMB 7.9 ± 3.6 counts, post-PHMB 2.2 ± 2.4 counts, <em>p </em>< 0.01). In addition, TBUT showed a statistically significant increase after PHMB lid scrub (pre-PHMB 2.7 ± 0.8 seconds, post-PHMB 3.4 ± 0.9 seconds, <em>p</em> < 0.01). Ocular surface disease index (OSDI) score was reduced in 28 of 30 patients (pre-PHMB 22.0 ± 10.7 points, post-PHMB 7.4 ± 6.0 points, <em>p</em> < 0.01). Conclusions: Eight weeks of treatment with polyhexamethylene biguanide lid scrub on Demodex blepharitis had good treatment efficacy for reducing Demodex counts and OSDI scores and increasing TBUT. J Korean Ophthalmol Soc 2014;55(4):493-497
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진균성 괴사성 공막염 환자에서 적절한 항진균제 치료 후 자가 귀구슬 연골막 이식술의 효과
문준형,김재찬,Jun Hyung Moon,Jae Chan Kim 대한안과학회 2013 대한안과학회지 Vol.54 No.12
Purpose: To compare the efficacy of an autologous tragal perichondrium graft after proper antifungal treatment between 2 cases of fungal necrotizing scleritis.<br /> Case summary: A 58-year-old female was referred to our clinic with fungal necrotizing scleritis of the left eye which had occurred after pterygium removal. Scleral melting around calcification was observed. After proper treatment with antifungal agents, the authors performed autologous tragal perichondrium graft; however, 3 months after surgery, a necrosis of sclera recurred and the, patient underwent additional treatment with antifungal agents. No complication has been observed up to 3 months postoperatively. A 36-year-old male visited our clinic with ocular pain and decreased visual acuity associated with necrotizing scleritis which occurred after local conjunctival resection. After 4 weeks of antifungal treatments, scleral lesions were stabilized and the authors confirmed negative findings with repetitive fungus smear test. Therapeutic autologous tragal perichondrium graft was performed, and no complication was observed 3 months postoperatively.<br /> Conclusions: When treating a patient with fungal necrotizing scleritis, preoperative antifungal therapy and confirmation of negative findings in repetitive fungus smear test are important. Autologus tragal perichondrium graft accompanied with proper antifungal therapy is an effective treatment of fungal necrotizing scleritis.<br /> J Korean Ophthalmol Soc 2013;54(12):1929-1934
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Rhodococcus fascians를 이용한 모래 컬럼내 디젤유 분해
문준형(Jun Hyung Moon),구자룡(Ja-Ryong Koo),윤현식(Hyun Shik Yun) 한국생물공학회 2011 KSBB Journal Vol.26 No.1
Contamination of soils, groundwater, air and marine environment with hazardous and toxic chemicals is major side effect by the industrialization. Bioremediation, the application of microorganism or microbial processes to degrade environmental contaminant, is one of the new environmental technologies. Because of low water solubility and volatility of diesel, bioremediation is more efficient than physical and chemical methods. The purpose of this study is biodegradation of diesel in sand by using Rhodococcus fascians, a microorganism isolated from petroleum contaminated soil. This study was performed in the column containing sand obtained from sea sides. Changes in biodegradability of diesel with various flow rates, inoculum sizes, diesel concentrations, and pH were investigated in sand column. The optimal condition for biodegradation of diesel by R. fascians in sand column system was initial pH 8 and air flow rate of 30 mL/min. Higher diesel degradation was achieved at larger inoculum size and the diesel degradation by R. fascians was not inhibited by diesel concentration up to 5%.
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유류 오염 토양에서 분리된 Rhodococcus fascians를 이용한 해수에서의 디젤유의 분해
구자룡(Ja-Ryong Koo),문준형(Jun Hyung Moon),윤현식(Hyun Shik Yun) 한국생물공학회 2009 KSBB Journal Vol.24 No.5
본 실험에 사용된 균주는 유류로 오염된 지역의 토양시료로부터 직접 분리한 Rhodococcus fascians로 이전 연구에서 항공유의 분해에 효과가 있는 것으로 밝혀진 균주이다. 디젤유가 항공유보다 R. fascians의 생장에 영향을 주는 것으로 나타났다. 해수중의 디젤 분해를 위해서는 2%이상의 접종량이 효과적이며 접종량이 증가할 경우 잔류량이 더 감소하였으나 큰 차이는 없었다. 해수중의 디젤이 5% 이상에서는 디젤유의 독성에 의해 R. fascians의 생장이 저해를 받아 디젤 잔류량이 높게 나타났다. R. fascians는 pH 8에서 가장 높은 디젤 분해속도를 보였으며 비교적 넓은 pH 범위에서 디젤 분해도가 유지되는 것으로 나타났다. R. fascians의 최적 성장온도 보다 높은 32℃에서는 디젤의 분해에 온도증가에 따른 자연분해의 영향이 큰 것으로 나타났다. R. fascians의 해수중 디젤유 분해의 최적온도는 27℃로 최적 생장온도에서 분해가 활발히 이루어지는 것을 알 수 있었다. Contamination of marine environment with hazardous and toxic chemicals is more common these days. Bioremediation is the application of microorganism or microbial processes to degrade environmental contaminant. Because of low water solubility and volatility of diesel, bioremediation is more efficient than physical and chemical methods. The objective of this study is biodegradation of diesel in sea water by using Rhodococcus fascians which is isolated petroleum-contaminated soil. R. fascians was cultured on sea water containing diesel to determine the diesel degradability. Changes in biodegradability of diesel with various inoculum sizes, diesel concentrations, initial pH, and culture temperature were analyzed by TPH analysis using gas chromatography. The inoculum size 2% was effective for biodegrdation of diesel in sea water by R. fascians. When diesel concentration was 5%, the growth of cell was inhibited by the toxicity of diesel. The optimal temperature and initial pH for degradation of diesel in sea water were 27℃ and pH 8.
KCI
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