http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Joonki Kim,Sung Hun Kim,Deuk-Sik Lee,Dong-Jin Lee,Soo-Hyun Kim,Sungkwon Chung,Hyun Ok Yang 고려인삼학회 2013 Journal of Ginseng Research Vol.37 No.1
This study examined the effect of fermented ginseng (FG) on memory impairment and β-amyloid (Aβ) reduction in models of Alzheimer’s disease (AD) in vitro and in vivo. FG extract was prepared by steaming and fermenting ginseng. In vitro assessment measured soluble Aβ42 levels in HeLa cells, which stably express the Swedish mutant form of amyloid precursor protein. After 8h incubation with the FG extract, the level of soluble Aβ42 was reduced. For behavioral assessments, the passive avoidance test was used for the scopolamine-injected ICR mouse model, and the Morris water maze was used for a transgenic (TG) mouse model, which exhibits impaired memory function and increased Aβ42 level in the brain. FG extract was treated for 2 wk or 4 mo on ICR and TG mice, respectively. FG extract treatment resulted in a significant recovery of memory function in both animal models. Brain soluble Aβ42 levels measured from the cerebral cortex of TG mice were significantly reduced by the FG extract treatment. These findings suggest that FG extract can protect the brain from increased levels of Aβ42 protein, which results in enhanced behavioral memory function, thus, suggesting that FG extract may be an effective preventive or treatment for AD.
Kim, Joonki,Lee, Hye-Jung,Nogoy, Franz Marielle,Yu, Dal-A,Kim, Me-Sun,Kang, Kwon-Kyoo,Nou, Illsup,Cho, Yong-Gu The Korean Society of Plant Biotechnology 2016 식물생명공학회지 Vol.43 No.3
Seed size traits are controlled by multiple genes in crops and determine grain yield, quality and appearance. However, the molecular mechanisms controlling the size of plant seeds remain unclear. We performed functional analysis of BrPATL4 encoding Sec14-like protein to determine the genetic architecture of seed size, shape and their association analyses. We used 60 $T_3$ transgenic rice lines to evaluate seed length, seed width and seed height as seed size traits, and the ratios of these values as seed shape traits. Pleiotropic effects on general architecture included small seed size, erect panicles, decreased grain weight, reduced plant height and increased sterility, which are common to other mutants deficient in gibberellic acid (GA) biosynthesis. To test whether BrPATL4 overexpression is deleterious for GA signal transduction, we compared the relative expression of GA related gene and the growth rate of second leaf sheath supplied with exogenous $GA_3$. Overexpression of BrPATL4 did not affect GA biosynthesis or signaling pathway, with the same response shown under GA treatment compared to the wild type. However, the causal genes for the small seed phenotype (D1, SRS1, and SRS5) and the erection of panicles showed significantly decreased levels in mRNA accumulation compared to the wild type. These results suggest that the overexpression of BrPATL4 can control seed size through the suppression of those genes related to seed size regulation. Although the molecular function of BrPATL4 is not clear for small seed and erect panicles of BrPALT4 overexpression line, this study provides some clues about the genetic engineering of rice seed architecture.
민준기(Joonki Min),팽성일(Seongil Paeng),조중현(Junghyun Cho) 전력전자학회 2011 전력전자학술대회 논문집 Vol.2011 No.7
태양광 시장의 확대과 스마트 그리드에 대한 기대로 태양광 인버터의 수요는 크게 증가할 것으로 예상되며, 이와 관련하여 기존에 없었던 새로운 기능에 대한 요구가 증가되고 있다. 대표적인 요구사항은 계통연계형 태양광 시스템에 에너지 저장 기능을 가지도록 하여 야간에도 발전기능을 유지하게 하는 것과 이와 비슷하게 독립형 태양광 시스템에 계통연계 기능을 가지도록 하여 에너지 저장장치의 충전이후 계통연계 발전을 하도록 하는 개념이다. 본 논문에서는 이러한 기능의 구현을 위한 요구사항에 대해 살펴보고, 향후 제품에 적용가능한 운전 시나리오를 검토한다.