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Jiang, Hua‐,Wei,Kim, Taeyeon,Tanaka, Takayuki,Kim, Dongho,Osuka, Atsuhiro WILEY‐VCH Verlag 2016 Chemistry Vol.22 No.1
<P><B>Abstract</B></P><P>Directly 2,12‐ and 2,8‐linked Zn<SUP>II</SUP> porphyrin oligomers were prepared from 2,12‐ and 2,8‐diborylated Zn<SUP>II</SUP> porphyrin by a cross platinum‐induced coupling with a 2‐borylated Zn<SUP>II</SUP> porphyrin end unit followed by a triphenylphosphine (PPh<SUB>3</SUB>)‐mediated reductive elimination. Comparative studies on the steady‐state absorption and fluorescence spectra and the fluorescence lifetimes led to a conclusion that the exciton in the S<SUB>1</SUB> state is delocalized over approximately four and two Zn<SUP>II</SUP> porphyrin units for 2,12‐ and 2,8‐linked Zn<SUP>II</SUP> porphyrin arrays, respectively.</P>
Compute-and-forward transmission scheme in cell-free massive MIMO systems
Jiang Hua,Kong Linghong,Du Sidan 한국통신학회 2023 ICT Express Vol.9 No.6
Cell-free massive multi-input-multi-output (MIMO) systems comprise a large number of distributed access points (APs) to serve a small number of user equipments (UEs). In this paper, compute-and-forward (CF) is investigated for uplink in cell-free massive MIMO. We propose a novel reverse CF precoding scheme for downlink transmission for cell-free massive MIMO. The APs send the linear equations of messages over a multiple access channel, and the UEs recover messages without interferences. The max–min power allocation is investigated to provide uniformly good service to all UEs. Numeral results demonstrate the performance improvement provided by the proposed reverse CF precoder against zero-forcing, conjugate beamforming, and linear minimum mean-square error precoder.
Jiang, Hua‐,Wei,Tanaka, Takayuki,Kim, Taeyeon,Sung, Young Mo,Mori, Hirotaka,Kim, Dongho,Osuka, Atsuhiro WILEY‐VCH Verlag 2015 Angewandte Chemie. international edition Vol.54 No.50
<P><B>Abstract</B></P><P>A set of 5,15‐biphenylene‐bridged porphyrin wheels, namely, [<I>n</I>]cyclo‐5,15‐porphyrinylene‐4,4′‐biphenylenes <B>[<I>n</I>]CPB</B>, have been synthesized through the platination of 5,15‐bis(4‐(pinacolboranyl)phenyl) nickel(II) porphyrin and subsequent reductive elimination of Pt<SUP>II</SUP>(cod)‐bridged cyclic porphyrin intermediates. The calculated strain energies for <B>[3]CPB</B>, <B>[4]CPB</B>, <B>[5]CPB</B>, and <B>[6]CPB</B> are 49.3, 32.9, 23.5, and 16.0 kcal mol<SUP>−1</SUP>, respectively. UV/Vis absorption spectra and cyclic voltammetry indicated characteristic ring‐size‐dependent absorption‐peak shifts and redox‐potential shifts, which presumably reflect the degree of strain in the π‐systems. Excitation‐energy hopping (EEH) times were determined to be 5.1, 8.0, 8.0, and 9.6 ps for <B>[3]CPB</B>, <B>[4]CPB</B>, <B>[5]CPB</B>, and <B>[6]CPB</B>, respectively, in a pump‐power‐dependent TA experiment.</P>
MicroRNA-338-3p as a novel therapeutic target for intervertebral disc degeneration
Jiang Hua,Moro Abu,Wang Jiaqi,Meng Dihua,Zhan Xinli,Wei Qingjun 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-
Recent studies have demonstrated the pivotal role played by microRNAs (miRNAs) in the etiopathogenesis of intervertebral disc degeneration (IDD). The study of miRNA intervention in IDD models may promote the advancement of miRNA-based therapeutic strategies. The aim of the current study was to investigate whether intradiscal delivery of miRNA can attenuate IDD development. Our results showed that miR-338-3p expression was significantly increased in the nucleus pulposus (NP) of patients with IDD. Moreover, there was a statistically significant positive correlation between the expression level of miR-338-3p and the severity of IDD. Our functional studies showed that miR-338-3p significantly influenced the expression of extracellular matrix synthesis genes, as well as the proliferation and apoptosis of NP cells. Mechanistically, miR-338-3p aggravated IDD progression by directly targeting SIRT6, a negative regulator of the MAPK/ERK pathway. Intradiscal injection of antagomir-338-3p significantly decelerated IDD development in mouse models. Our study is the first to identify miR-338-3p as a mediator of IDD and thus may be a promising target for rescuing IDD.
Prediction of Power Generation in China Using Process Neural Network
Jianghua Ge,Jiwei Wen,Chuntao Zhang,Yaping Wang,Gang Ding 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.5
The power generation prediction problem can be seen as a time series prediction problem in nature. The traditional time series prediction methods based on regression analysis do not take account into the time accumulation effect existed in the time series due to their discrete input values. This limitation causes the low prediction accuracy of the time series prediction methods based on regression analysis. To solve this problem, a power generation time series prediction model based on the process neural network is proposed. The inputs of the proposed prediction model can be continuous time-varying functions. The time accumulation effect existed in the power generation time series can be expressed and computed by the integration operator of the process neural network. The proposed prediction model is trained and the efficiency of the proposed prediction model is tested by the month power generation data form January 2001 to April 2012, and the comparison experiment results indicate that the process neural network performs better than the auto regression analysis.
Research on the Error Detection Technology of Complex Parts based on Improved Bee Colony Algorithm
Jianghua Ge,Huihui Zhang,Yaping Wang,Xiulin Sui,Yongguo Sun 보안공학연구지원센터 2015 International Journal of Security and Its Applicat Vol.9 No.12
For Parts of complex structures with multiple characteristics, traditional methods are often difficult and inefficient, so the three-dimensional detection techniques have been developed. But the detection used for the complex structural components still get some problems, such as : it’s difficult to collect data of complex structural components in the data collection process, because of size is always limited ; features of parts retained difficultly in data processing; there are many iterations and calculations in the optimization algorithm of geometric error evaluation, and the search direction is blind. In this paper, the improved colony algorithm is used to get the cylindrical error by establishing the mathematical model with the point cloud data that has been processed. First, collect data acquisition of more structural parts with hand-held laser scanners; Secondly, denoise and streamline the raw point cloud collected before, and then make registration and alignment with the actual CAD model of part; Finally, according to the resultant point cloud data above, in accordance with the principle of minimum condition assessment, establish evaluation model of cylinder error based on improved bee colony algorithm. Experimental results show that for various structural parts, the precision of this detection method is high enough, and detecting speed is also fast.
Jianghua Ou,Tao Wu,Rolf Sijmons,Duo Ni1,Wenting Xu,Halmurat Upur 한국유방암학회 2013 Journal of breast cancer Vol.16 No.1
Purpose: The aim of this study is to further understand the status of BRCA1 and BRCA2 mutation among Chinese high-risk breast cancer patients in multiple-ethnic regions of China. Methods: A total of 79 blood samples of high-risk breast cancer patients from Xinjiang Uyghur autonomous region were analyzed by PCR-DHPLC sequencing analysis. Results: Analysis with full length of the two genes identified a total of 6 deleterious mutations (2073delA, 2394C-T [Q759X] and IVS16+1G>A in BRCA1; 1627A-T [K467X], 6873delCTCC and 9481delA in BRCA2) in this cohort. The prevalence of BRCA1/2 germline mutation was about 7.6% (6/79) in the Xinjiang multiple ethnic region of China. Among them, 3 novel deleterious mutations, 2073delA in BRCA1 (Han ethnic Chinese) and BRCA2 variants 6873delCTCC and 9481delA (both are Kazakh ethnic Chinese), were identified and they had never been reported in breast cancer information core (BIC) database before. 2394C-T (Q759X) and IVS16+1G>A, in BRCA1 and BRCA2 variants 1627A-T were previously reported in other populations but not Chinese. Among 6 of the BRCA-related tumors, three BRCA1- and one BRCA2-associated tumors were in triple negative (estrogen receptor, progesterone receptor, and HER2 negative expressed) status and exhibited a high tumor grade. So far none of these 6 deleterious mutations were reported in ethnic Han Chinese. Conclusion: BRCA germline mutation in Chinese multiple ethnicity region may exhibit different genotypes compared to ethnic Han Chinese in other regions. These differences may arise from interaction of genetic background and environmental factors.