Localisation of DNA Topoisomerase llα in Mouse Erythroleukemia Cells

Ivanova, emilia Ch.,Donev, Rossen M.,Djondjurov, Lalio P. Korean Society of Molecular Biology 1999 Molecules and cells Vol.9 No.3

Analysis of Chromosome Lesions in Women with Benign Breast Diseases, Residing in the Territories Contaminated as a Result of the Chernobyl Accident

Ivanova, T.,Smirnova, I.,Kondrashova, T.,Yun, Yeon Sook,Song, Jie Young,Han, Young Soo Trans Tech Publications, Ltd. 2005 Key Engineering Materials Vol.277 No.-

<P>Spontaneous levels of the chromosome aberrations in the peripheral lymphocytes of 173 women were analyzed in the course of a medical examination of the residents of the Bryansk District territories (Klintsy Region, and the town of Klintsy) contaminated after the Chernobyl NPP accident in April 1986. The study population included only women who had been premenopausal at the time of the accident (mean age in 1986 was 23.9±0.7 years, ranging 2 to 56 years). The territory contamination with 137Cs ranged from 1.8 to 23.7 Ci/km2, the mean value being 7.5±0.2 Ci/km2. The range of the calculated absorbed thyroid doses was 30 to 340 mGy (in average, 52.3±3.3 mGy). The number of women with benign breast diseases (BBD) was 116 (67%). All recognizable chromosome lesion types were scored in the first in vitro division metaphases stained with azure-eosin. The mean total aberration frequency in the sample studied was 3.5±0.2 per 100 metaphases, the main contribution being made by the chromatid deletions, which is typical for a normal spontaneous aberration pattern. Based on the results of the cytogenetic analysis, the study population was subdivided into two groups. Group A (128 women) included subjects who showed normal patterns of spontaneous chromosome aberrations. Abnormal patterns, including the aberration frequencies significantly (at p<0.05) exceeding the mean group value and/or the presence of chromosome type exchange aberrations, were found in 45 women (group B). Statistical hypotheses on the possible correlations between the cytogenetic anomalies, BBD, level of the territory radiation contamination, and the absorbed thyroid dose were tested. The proportion of women with BBD was approximately the same in groups A and B (68 and 64%, respectively; p=0.665), which did not allow us to state that abnormal chromosome patterns can be used as diagnosis markers. The data obtained showed some positive trends between the cytogenetic anomalies, breast disorders, level of the territory contamination and the thyroid dose. In addition, it is interesting to note that the inclusion of the body mass index (BMI) into the data analysis showed that, both in women with cytogenetic anomalies (group B) and among the women with BBD, this index was essentially lower than in the respective comparison groups. The BMI differences could not be explained by the age differences, since the latter were insignificant in all the cases (p>0.8).</P>

Peculiarities of the E-commerce Development in the Conditions of Digital Economy

Ivanova, Nataliia,Kublitska, Olena,Krupitsa, Iryna,Dybchuk, Luidmyla,Koval, Kristina,Hanieieva, Tetiana International Journal of Computer ScienceNetwork S 2021 International journal of computer science and netw Vol.21 No.12

The article is devoted to current issues of the development of e-commerce, which is gaining more importance in the conditions of widespread quarantine restrictions. As a result, of the research the importance of digitalization as a driver of economic development is substantiated and the main business models of e-commerce and their modifications are examined. The peculiarities of e-commerce in the context of digital economy were analyzed and their current state was established. Identified the main trends in the development of e-commerce at the current stage, which allowed to identify problem areas that require further study and evaluation. Presented the results of the market research of decorative cosmetics, based on which the summarized set of problems that affect the online sales in this segment of the market.

Marketing Strategy of the Small Business Adaptation to Quarantine Limitations in the Sphere of Trade Entrepreneurship

Ivanova, Nataliia,Popelo, Olha,Avhustyn, Ruslan,Rusak, Olena,Proshchalykina, Alina International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.1

The article considers the peculiarities of developing a marketing strategy for the adaptation of small businesses to quarantine restrictions in the field of commercial entrepreneurship. The importance of reformatting the existing marketing strategy in connection with the change of key conditions of trade activity with the introduction of quarantine restrictions due to the covid19 virus epidemic is substantiated. Quarantine restrictions and the temporary introduction of lockdown in various countries around the world, including Ukraine, have not only caused a crisis for small businesses. But they became a shock therapy and accelerated the digitalization of retail. Trends in digitalization and development of digital infrastructure allow both to adapt the structures of commercial entrepreneurship to the current conditions, and set directions for development in the long run. Particular attention in the article is paid to changing the business model and automation of sales processes based on the introduction of vending. The preconditions and existing experience of vending in Ukraine are analyzed. An outline of the business model of the project for the sale of goods through vending machines has been developed.

Mobile Banking Service in Mongolia: The Role of Online Convenience on the Acceptance and Use Behavior

Ivanova, Aisena,Noh, Grimm Korean Marketing Association 2022 ASIA MARKETING JOURNAL Vol.24 No.2

The goal of this study is to scrutinize the impact of individual online convenience dimensions on mobile banking acceptance and use in Mongolia. A total of 211 valid responses were collected from Mongolian university students who currently use mobile banking application services from local banks. The SmartPLS 3.3 software was used to conduct the confirmatory factor analysis and test the hypotheses. Using structural equation modelling, this research discovered that access convenience, transaction convenience, and possession/post-possession convenience are the main constructs related to the adoption of mobile banking services. Perceived innovation showed a significant positive effect on the adoption of mobile banking technologies. Through practical and theoretical implications, this research aims to assist mobile banking service channels of local and international banks in Mongolia. Identifying which online convenience dimensions impact the adoption and use of mobile banking will contribute to the adoption of competitive strategies for financial institutions and banks.

Study on Digitalisation of the Tourism Industry in the Regions of the Russian Federation

Ivanova, Raisa,Skrobotova, Olga,Polyakova, Irina,Karaseva, Galina,Strelnikova, Marina International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.8

The relevance of the published study lies in the fact that since the introduction of the first Global Distribution System, new information and communication technologies have constantly been changing the tourism industry. In the context of a current digital environment, travel agencies can't avoid participating in digital transformation processes aimed at rethinking operational models, skills, and organisational structures in the regions. This publication aims to present and provide a critical overview of digitalisation processes in tourism development in the regions of the Russian Federation, as well as to reflect on the challenges to the widespread digitalisation processes in the regional tourism sector. The subject of research is digitalisation processes, as they radically transform the modern tourism industry, in the regions as well. The pragmatic research paradigm was considered the most appropriate for the study of tourism digitalisation processes in the regions, as it does not require the selection of a specific theoretical basis for data collection. The pragmatic approach forms an alternative to classical theoretical approaches and serves as a particular type of grounded theory, combining both inductive and deductive methods. No software was used for the inductive part of the analysis. The deductive part was conducted using the qualitative data analysis software Nvivo 11. Given the wide diversity of interested parties in the regional tourism digital area, a stratified purposive sampling method was preferred due to its ability to adequately represent the full picture of the phenomenon under study. The selection and stratum criteria were chosen to maximise the representation of different perspectives in the regional tourism digital area. The novelty of the study is due to the digitalisation processes, with an implication of new needs, while opening up promising opportunities for more productive tourism business in the regions of the Russian Federation. Currently, e-tourism in the Russian Federation has become a subject of lively debate among scholars and practitioners. However, the involvement of advanced digitalisation technologies in the field of information processes in the regions of the Russian Federation is of a very sporadic character.

Breadcrumb as a New Substrate for Trametes versicolor and Schizophyllum commune Submerged Cultivation

Ivanova, Tetiana S.,Bisko, Nina A.,Krupodorova, Tetiana A.,Barshteyn, Victor Yu. The Korean Society for Microbiology and Biotechnol 2014 한국미생물·생명공학회지 Vol.42 No.1

A new substrate, breadcrumbs, was investigated for biomass accumulation, the pH of the cultural broth, the formation of primary metabolites such as the proteins and endopolysaccharides of Schizophyllum commune 1768 and Trametes versicolor 353, as well as its bioconversion efficiency. The results showed that S. commune gives more mycelial mass ($23.96{\pm}0.8g/l$) and in a shorter period (4 days) than T. versicolor ($15.76{\pm}0.5g/l$ in 5 days). The pH values changed from the initial 6.1 to 3.6 in S. commune cultural broth and to 4.4 in T. versicolor cultural broth. Maximal endopolysaccharide content in the mycelia of S. commune and T. versicolor were 7.13% and 6.42%, correspondingly. Crude protein content in S. commune mycelium was 18.83 % on the 4th day of cultivation, and 20.03%, in the mycelium of T. versicolor, on the 6th day of cultivation. Kinetic parameters for the quantitative estimation of cultivation efficiency were calculated for biomass, endopolysaccharide, and crude protein concentrations.

Peculiarities of Tundra Soil in the Northeastern Yakutia

Alexandra Ivanova,Roman Desyatkin 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Impact of Cross-Section-Covariance Data on Results of High-Confidence Criticality Validation

T. Ivanova,I. Duhamel,E. Letang 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23

Neutron cross-section-covariance data are used for high-confidence criticality validation based upon ``adjustment'' method. To investigate how they impact results of the validation study, three sets of the covariance data (ENDF/B-V, JENDL-3.2, and TENDL-2009) were used to establish prior and posterior (post-adjusted) uncertainties for application cases with typical uranium dioxide fuel used in criticality safety analysis. Data from the French Fission Product integral experiments were used for the adjustment. The experiments were thoroughly selected and analysed to establish correlation between experimental uncertainties. It is shown the k_(eff) uncertainties due to the original covariance data differ significantly. While the post-adjusted k_(eff) uncertainties decrease significantly and are similar, irrespective of the initial matrices, for the applications systems which are similar to the experiments in k_(eff) sensitivities to nuclear data. This demonstrates a prevalent role of the integral experiments in the uncertainty assessment with the adjustment technique if enough reliable experiments are available. Three sets of full initial and post-adjusted matrices of contributions to overall k_(eff) uncertainties due to neutron cross sections are compared. The comparison shows that the post-adjusted uncertainties are decreased because of negative cross-correlations, which appear between reactions for the same and different isotopes, rather than because of reduction of uncertainties.

Texture and microstructure development in hydroxyapatite coatings deposited by means of RF-magnetron sputtering

Anna IVANOVA,Maria SURMENEVA,Roman SURMENEV,Diederik DEPLA 한국진공학회 2016 한국진공학회 학술발표회초록집 Vol.2016 No.8