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( Kannapu Hariprasad Reddy ),서영웅 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.1
The aim of the present research is to synthesize long chain aliphatic ketones (LCAK) from bio-based small carbon molecules via cross aldolcondensation over Cu/CeO<sub>2</sub> at elevated reaction temperature 240°C under nitrogen atmosphere using high pressure autoclave reactor. LCAK can be used as jet fuels and petrochemicals which are alternative to conventional fuels. Acetone and n-butanol are bio-based key reactants for the synthesis of LCAK. The Cu/CeO<sub>2</sub> catalysts were developed in two different manners such as (i) citric acid method and (ii) solvothermal method. Interestingly, the catalyst prepared by citrate method exhibited an excellent catalytic activity compared to that of solvothermal catalyst. The total yield of LCAK was about 73% while the selectivity of 6-undecanone was achieved about 44 % over Cu-CeO<sub>2</sub> citrate method catalyst. The prepared catalysts were well characterized using different analytical techniques. Finally, the activity and characterization results were well correlated.
Srividhya, Akkareddy,Vemireddy, Lakshminarayana R.,Sridhar, Sakile,Jayaprada, Mndduluru,Ramanarao, Puram V.,Hariprasad, Arremsetty S.,Reddy, Hariprasad K.,Anuradha, Ghanta,Siddiq, Ebrahimali 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.1
Moisture stress is the major constraint to rice production and its stability in rainfed, mainly irrigated, and aerobic environments. Identification of genomic regions conferring tolerance to stress would improve our understanding of the genetics of stress response and result in the development of drought tolerant cultivars. In the present study, quantitative trait loci for drought response related traits and as well as grain yield were identified using a set of 140 recombinant inbred lines derived from a cross between the popular high-yielding variety, IR64 and the landrace, INRC10192. A total of 36 QTL were identified for grain yield and its components under control and stress conditions. Strikingly, a QTL cluster flanked by the markers RM38 and RM331 on chromosome 8 was found to be associated with grain yield, plant height, no. of productive tillers, chaffy grains, and spikelet fertility on secondary rachis and biomass under stress treatment. The genomic regions associated with these QTL under drought stress will be useful for the development of marker-based breeding for drought tolerant, high-yielding varieties suited to drought-prone areas.
Akkareddy Srividhya,Lakshminarayana R Vemireddy,Sakile Sridhar,Mudduluru Jayaprada,Puram V Ramanarao,Arremsetty S Hariprasad,Hariprasad K Reddy,Ghanta Anuradha,Ebrahimali Siddiq 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.1
Moisture stress is the major constraint to rice production and its stability in rainfed, mainly irrigated, and aerobic environments. Identification of genomic regions conferring tolerance to stress would improve our understanding of the genetics of stress response and result in the development of drought tolerant cultivars. In the present study, quantitative trait loci for drought response related traits and as well as grain yield were identified using a set of 140 recombinant inbred lines derived from a cross between the popular high-yielding variety, IR64 and the landrace, INRC10192. A total of 36 QTL were identified for grain yield and its components under control and stress conditions. Strikingly, a QTL cluster flanked by the markers RM38 and RM331 on chromosome 8 was found to be associated with grain yield, plant height, no. of productive tillers, chaffy grains, and spikelet fertility on secondary rachis and biomass under stress treatment. The genomic regions associated with these QTL under drought stress will be useful for the development of marker-based breeding for drought tolerant, high-yielding varieties suited to drought-prone areas.
Esophageal Submucosal Injection of Capsaicin but Not Acid Induces Symptoms in Normal Subjects
( Robert H Lee ),( Hariprasad Korsapati ),( Vikas Bhalla ),( Nissi Varki ),( Ravinder K Mittal ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2016 Journal of Neurogastroenterology and Motility (JNM Vol.22 No.3
Background/Aims Transient receptor potential vanilloid-1 (TRPV1) is a candidate for mediating acid-induced symptoms in the esophagus. We conducted studies to determine if the presence of acid in the mucosa/submucosa and direct activation of TRPV1 by capsaicin elicited symptoms in normal healthy subjects. We also studied the presence of TRPV1 receptors in the esophagus. Methods Unsedated endoscopy was performed on healthy subjects with no symptoms. Using a sclerotherapy needle, normal saline (pH 2.0- 7.5) was injected into the mucosa/submucosa, 5 cm above the Z line. In a separate group of healthy subjects, injection of capsaicin and vehicle was also studied. Quality of symptoms was reported using the McGill Pain Questionnaire, and symptom intensity using the visual analogue scale (VAS). Immunohistochemistry was performed on 8 surgical esophagus specimens using TRPV1 antibody. Results Acid injection either did not elicit or elicited mild symptoms in subjects at all pH solutions. Capsaicin but not the vehicle elicited severe heartburn/chest pain in all subjects. Mean VAS for capsaicin was 91 ± 3 and symptoms lasted for 25 ± 1 minutes. Immunohistochemistry revealed a linear TRPV1 staining pattern between the epithelial layer and the submucosa that extended into the papillae. Eighty-five percent of papillae stained positive for TRPV1 with a mean 1.1 positive papillae per high-powered field. Conclusions The mechanism of acid-induced heartburn and chest pain is not the simple interaction of hydrogen ions with afferents located in the esophageal mucosa and submucosa. TRPV1 receptors are present in the lamina propria and their activation induces heartburn and chest pain. (J Neurogastroenterol Motil 2016;22:436-443)
Bommisetty Reddyyamini,Chakravartty Navajeet,Hariprasad K. R.,Rameshbabu P.,Sudhakar P.,Bodanapu Reddaiah,Naik Jeevula Bhukya,Reddy B. V. Bhaskar,Lekkala Sivrama Prasad,Gupta Saurabh,Tanti Bhaben,Lach 한국식물생명공학회 2023 Plant biotechnology reports Vol.17 No.2
The grain number is one of the highly complex and crucial traits determining the grain yield in rice. To identify grain number QTLs in rice, we employed the QTL-seq approach in the 297 F2 population derived from the cross between BPT5204 and NLR33892. In this investigation, five regions viz., qGN1, qGN3, qGN7, qGN9, and qGN12 on chromosomes 1,3,7,9, and 12, respectively, were identified as QTLs governing grain number per panicle in rice. To verify the QTLs identified in the present study, traditional QTL mapping was carried out using InDel markers and previously reported SSRs in the QTL region. From qGN12 QTL, RM6953 showed a significant association with the number of grains per panicle with a phenotypic variance of 24.58, 22.10, and 17.20% in F2, F2:3, and BC1F2 populations, respectively, at < 0.0001 P value, indicating major QTL. From genome resequencing data, a missense variance was observed in the exonic region of LOC_Os12g39330 gene controlling AP2 domain-containing protein which plays an important role in seed development in rice. Hence, this QTL can be a potential target for map-based cloning and marker-assisted transfer to enhance the grain number in rice.