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Ehud Elnekave,Boris Even-Tov,Boris Gelman,Beni Sharir,Eyal Klement 대한수의학회 2015 Journal of Veterinary Science Vol.16 No.1
Routine and emergency vaccination of small ruminants against foot-and-mouth disease (FMD) is mandatory in many endemic countries, yetdata on the field effectiveness of the vaccines used is scarce. We conducted an investigation of a serotype O FMD outbreak that took placein a sheep and goat pen, and estimated the effectiveness of various routine vaccination statuses. We also evaluated the protection providedby colostrum administration and emergency vaccination. Animals which were routinely vaccinated twice were not clinically affected whiledisease incidence was observed among animals routinely vaccinated only once (p = 0.004 according to a two-sided Fisher’s exact test). Ingroups vaccinated only once, there was a significant association between the average time that elapsed since last vaccination and the diseaseincidence (n = 5; Spearman correlation coefficient: rs = 1.0, p < 0.01). In addition, non-vaccinated lambs fed colostrum from dams vaccinatedmore than 2 months before parturition had a mortality rate of 33%. Administration of emergency vaccination 2 days after the occurrence ofthe index case was the probable reason for the rapid blocking of the FMD spread within 6 days from its onset in the pen.
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