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Influence of the laser pulse shape in the treatment of stones in the upper urinary tract
Abdulmajeed Alghamdi,Alexander Kretschmer,Christian G. Stief,Frank Strittmatter 대한비뇨의학회 2020 Investigative and Clinical Urology Vol.61 No.6
Purpose: Urinary stones can be successfully treated using a Holmium: Yttrium-Aluminum-Garnet (Ho: YAG) laser. Regarding success rates, laser pulse energy, frequency, and pulse width are well-known contributing factors. Whether the pulse shape might be a further factor influencing the laser efficiency is unclear. This study aimed to evaluate different modes of laser pulse shapes in a real-world setting. Materials and Methods: The Dornier Medilas® H Solvo (Weßling, Germany) was used in the treatment of ureter and kidney stones. Patients were randomized into standard pulse shape (SPS) and new pulse shape groups (NPS1; ureter) and (NPS2; kidney pelvis), depending on the stone localization. The primary endpoint was laser efficiency defined as mm3 stone destruction per overall operating time. Secondary endpoints encompassed number of stone recoveries and stone-free rate. Results: Altogether 145 patients (24 SPS vs. 32 NPS1; 51 SPS vs. 38 NPS2) were included. No differences in sex, age, body mass index, stone localization and stone composition were found, except for preoperative stone size (133±95 [SPS] vs. 197±139 [NPS1] mm3; p=0.023) and (348±298 [SPS] vs. 525±429 [NPS2] mm3; p=0.042). Regarding the primary endpoint, a significant increase in laser efficiency could be detected for the NPS1 and NPS2 groups compared to the SPS groups (39.9±44.9 vs. 28.8±30.2 and 51.7±61.3 vs. 22.4±24.2 mm3/min [mean±standard deviation]). No statistically significant differences were found for secondary endpoints and perioperative complication rates. Conclusions: Efficiency of the Ho: YAG laser can be positively influenced by different pulse shapes. This adds the variable of individualized intraoperative decision making.
Alsultan, Abdulmajeed S. Techno-Press 2021 Advances in nano research Vol.11 No.1
This study analyzes the influence of surface effects on transportation vibrational properties. The evaluation of vibration impacts was done in accordance with the standards laid out in ISO 2631-1 for convenience on public transport (bus). The QCM (Quarter Car Model) with a quarter vehicle mass and variable was evaluated on exchange force between paving and three vehicle typologies (car, bus, and truck) using Matlab. The driver's, passengers in the center section, and passengers in the rear overhang's comfort is evaluated. The ten-degree oscillatory bus model has been designed for analytical requirements. First, the vibration propagation effects of different bus types are examined. Numerical methods are next briefly addressed to vibration propagation modeling inside the path and in the soil. Then a detailed discussion on the development of numerical models with an examination of the appropriateness of various modeling techniques for vehicle impact analysis will be given. Bus excitation has been created by using the asphalt-concrete road roughness power-spectral density as stated in the H. Braun model. This article illustrates how this dynamic overcharge might be predetermined according to the deterioration of the pavements'surface. This is a valuable resource for the design and maintenance of road pavements.
Android Operating System: Security Features, Vulnerabilities, and Protection Mechanisms
AlJeraisy, Lulwa Abdulmajeed,Alsultan, Arwa International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.11
In the age of smartphones, users accomplish their daily tasks using their smartphones due to the significant growth in smartphone technology. Due to these tremendous expansions, attackers are highly motivated to penetrate numerous mobile marketplaces with their developed malicious apps. Android has the biggest proportion of the overall market share when compared to other platforms including Windows, iOS, and Blackberry. This research will discuss the Android security features, vulnerabilities and threats, in addition to some existing protection mechanisms.
Preparation and Structure Properties of LaBa2Cu2O9, LaBa2CaCu3O12 and LaBa2Ca2Cu5O15 Perovskites
Kareem Ali Jasim,Hind Abdulmajeed Mahdi,Rafah Ismael Noori,Marwa Ayad Abdulmajeed 한국재료학회 2023 한국재료학회지 Vol.33 No.9
In this study we examine variations in the structure of perovskite compounds of LaBa2Cu2O9, LaBa2CaCu3O12 and LaBa2Ca2Cu5O15 synthesized using the solid state reaction method. The samples’ compositions were assessed using X-ray fluorescence (XRF) analysis. The La: Ba: Ca: Cu ratios for samples LaBa2Cu2O9, LaBa2CaCu3O12 and LaBa2Ca2Cu5O15 were found by XRF analysis to be around 1:2:0:2, 1:2:1:3, and 1:2:2:5, respectively. The samples’ well-known structures were then analyzed using X-ray diffraction. The three samples largely consist of phases 1202, 1213, and 1225, with a trace quantity of an unknown secondary phase, based on the intensities and locations of the diffraction peaks. According to the measured parameters a, b, and c, every sample has a tetragonal symmetry structure. Each sample’s mass density was observed to alter as the lead oxide content rose. Scanning electron microscope (SEM) images of the three phases revealed that different Ca-O and Cu-O layers can cause different grain sizes, characterized by elongated thin grains, without a preferred orientation.
Irshad, Mohammad,Mandal, Raju Kumar,Al-Drees, Abdulmajeed,Khalil, Mahmoud Salah,Abdulghani, Hamza Mohammad Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14
Background: Earlier studies on the association between p53 codon 72 Arg>Pro polymorphism and cancer risk were inconclusive and conflicting for the Saudi population. Therefore, we performed a meta-analysis to investigate the relationship between the codon 72 Arg>Pro polymorphism and overall cancer risk in Saudi Arabia. Materials and Methods: We searched all eligible published studies and data were pooled together to perform the meta-analysis. Pooled odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated for homozygous, heterozygous, dominant and recessive genetic models. Results: A total of five eligible published studies covering 502 cancer cases and 784 healthy controls were included in the meta-analysis. No publication bias was detected in this study. The results suggested that the variant (Pro vs Arg: p=0.960; OR=1.004, 95% CI=0.852-1.183), homozygous (Pro.Pro vs Arg.Arg: p=0.970; OR=1.006, 95% CI=0.729-1.390), heterozygous (Arg.Pro vs Arg.Arg: p=0.473; OR=0.783, 95% CI=0.402-1.527) carriers were not associated with overall cancer risk. Similarly, dominant (Pro.Pro+Pro.Arg vs Arg.Arg: p=0.632; OR=0.886, 95% CI=0.540-1.454) and recessive (Pro.Pro vs Pro.Arg+Arg.Arg: p=0.269; OR=1.163, 95%CI=0.890-1.521) models also did not indicate increased risk of cancer. Conclusions: The current meta-analysis suggests that the codon 72 Arg>Pro polymorphism of the p53 gene might not contribute to cancer susceptibility in Saudi population. Future well designed large case control studies are needed to validate our findings.
Taif Fawaz AlNojaidi,Sultan Nasser Alaqil,Abdullh Zafer AlQhtani,Abdulmajeed Saad Alhadlaq 대한미용성형외과학회 2023 Archives of Aesthetic Plastic Surgery Vol.29 No.1
Background Plastic surgery is considered one of the most competitive specialties globally. In Saudi Arabia, it was established in 2001 in the central province (Riyadh) and then expanded in 2009 to include more eastern and western provinces. Previous research has identified several factors that impact pursuing a career in plastic surgery. Methods This cross-sectional study was conducted through a five-page, five-section questionnaire distributed among senior medical students and interns using online platforms between August 2021 and January 2022. The overall number of questions was 25, which tackled different aspects, including sociodemographic characteristics (i.e., age and gender); the duration of the elective rotation; supervisor during the elective; encouraging, discouraging, and influencing factors; and the rating of participants’ desire to become a plastic surgeon. Results After elective training, the most common factor that influenced medical students to choose a plastic surgery career was exposure to a variety of cases (favorable to agree: 80.4%), followed by involvement in clinical activities (i.e., rounding, clinics, and case presentations) (favorable to agree: 70.6%). On the contrary, the most common factor discouraging students from choosing a plastic surgery career after elective training was plastic surgery being a competitive specialty for matching (favorable to agree: 62.7%), followed by the intense workload (favorable to agree: 56.9%). Conclusions Medical students were more likely than medical interns to explore a career in plastic surgery. Exposure to a variety of cases, inspiring mentors, and a decent amount of time spent in the operating room were the most influential factors.
apoptosis in N-acetyl-p-aminophenol-induced liver injury in mice is tissue factor dependent
Mohamed Sadek Abdel-Bakky,Gouda Kamel Helal,El-Sayed Mohamed El-Sayed,Elham Amin,Abdulmajeed Alqasoumi,Ahmad Alhowail,Eman Sayed Said Abdelmoti,Ahmed Saad Saad 대한생리학회-대한약리학회 2021 The Korean Journal of Physiology & Pharmacology Vol.25 No.5
Tissue factor (TF) activates the coagulation system and has an important role in the pathogenesis of various diseases. Our previous study stated that retinoid receptors (RAR-α and RXR-α) are released as a lipid droplet in monocrotaline/ lipopolysaccharide-induced idiosyncratic liver toxicity in mice. Herein, the interdependence between the release of retinoid receptors RAR-α and RXR-α and TF in Nacetyl- p-aminophenol (APAP)-induced mice liver toxicity, is investigated. Serum alanine transaminase (ALT) level, platelet and white blood cells (WBCs) counts, protein expression of fibrin, TF, cyclin D1 and cleaved caspase-3 in liver tissues are analyzed. In addition, histopathological evaluation and survival study are also performed. The results indicate that using of TF-antisense (TF-AS) deoxyoligonucleotide (ODN) injection (6 mg/kg), to block TF protein synthesis, significantly restores the elevated level of ALT and WBCs and corrects thrombocytopenia in mice injected with APAP. TF-AS prevents the peri-central overexpression of liver TF, fibrin, cyclin D1 and cleaved caspase- 3. The release of RXR-α and RAR-α droplets, in APAP treated sections, is inhibited upon treatment with TF-AS. In conclusion, the above findings designate that the released RXR-α and RAR-α in APAP liver toxicity is TF dependent. Additionally, the enhancement of cyclin D1 to caspase-3-dependent apoptosis can be prevented by blocking of TF protein synthesis.