http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
혈액종양 : 맥락막으로 전이된 대장암 환자에서 시행된 완화적 방사선 치료 1예
허솔미 ( Sol Mi Huo ),안호정 ( Ho Jung An ),이종은 ( Jong Eun Lee ),음상훈 ( Sang Hoon Eum ),김민영 ( Min Young Kim ),장유나 ( Yu Na Jang ),심병용 ( Byoung Yong Shim ) 대한내과학회 2015 대한내과학회지 Vol.89 No.6
Choroidal metastasis from colorectal cancer is very rare and has not been reported before in Korea. We report a case of eye hyperemia and discomfort in a patient with advanced colon cancer. Orbit magnetic resonance imaging and positron emission tomography revealed an enhancing mass within the temporal side of the left orbit, suggestive of choroidal metastasis from the colorectal adenocarcinoma. The condition’s rarity may be due to the long and distant pathway from the colon to the orbit. The presentation usually suggests extensive hematogeneous cancer dissemination and a poor prognosis. However, palliative radiotherapy may be an effective treatment for choroidal metastasis. (Korean J Med 2015;89:723-727)
증 례 : EGFR 돌연변이와 ALK 재배열 공존하는 폐선암 환자 1예
김민아 ( Min Ah Kim ),강진형 ( Jin Hyoung Kang ),김인호 ( In Ho Kim ),김태정 ( Tae Jung Kim ),김승준 ( Seung Joon Kim ),성숙환 ( Sook Whan Sung ),허솔미 ( Sol Mi Huo ) 대한내과학회 2016 대한내과학회지 Vol.90 No.1
A 58 year-old woman was diagnosed with lung adenocarcinoma (cT3N1M0). We detected a point mutation in epidermal growth factor receptor (EGFR) exon 21 (L858R) and an echinoderm microtubule-associated protein-like 4- anaplastic lymphoma kinase (ALK) rearrangement. The patient was treated with preoperative neoadjuvant chemotherapy and underwent a left lower lobectomy with mediastinal lymph node dissection. However, we could not detect any mutation in EGFR or the ALK rearrangement from the tumor tissue removed. Then, 70 days after completion of adjuvant chemotherapy, she visited our outpatient clinic with diminished visual accuracy and tinnitus. A single brain metastatic lesion was seen on brain magnetic resonance imaging. She underwent surgical removal of the brain mass, which showed a mutation of EGFR, exon 21, but no ALK rearrangement. We report this unusual case of lung adenocarcinoma with a coexisting EGFR mutation and ALK rearrangement, and identify gene alterations before chemotherapy, after chemotherapy, and at recurrence. (Korean J Med 2016;90:72-77)