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RISS 인기검색어
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- 저자 : 정순재(Soon-Je Jung) (검색결과 2 건)
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Borrmann 4형 위암 환자에서 장기 생존자의 특성과 예후인자
류제호 ( Je Ho Ryu ),육정환 ( Jeong Hwan Yook ),김병식 ( Byung Sik Kim ),오성태 ( Sung Tae Oh ),정순재 ( Soon Tae Jung ),최원용 ( Won Yong Choi ) 대한소화기학회 2003 대한소화기학회지 Vol.41 No.1
Background/Aims: Prognosis of Borrmann type 4 gastric cancer is still poor. To improve the prognosis of patients with Borrmann type 4 gastric cancer, it is important to understand the clinicopathological features of patients with a long-term survival. Thus, we compared the characteristics of the patients with a long-term survival (survival duration more than 5 years) with patients with a short-term survival. Methods: We analyzed retrospectively 370 patients who were diagnosed as having Borrmann type 4 gastric cancer and underwent gastric resection between 1989 to 1997 at our hospital. Twenty-one percent of the patients survived longer than 5 years. For comparison of clinicopathlogical factors, the chi-square test was used and multivariate analysis was performed in order to focus on prognostic factors. Results: The 5-year survival rate of the total 370 patients was 21%. Significant difference was noted in the following variables: location of tumor, size, peritoneal metastsis, hepatic metastasis, lymph node metastasis, depth of invasion, stage and curability. In multivariate analysis, the location of tumor was the most significant independent prognostic factor. Conclusions: These results suggest that even in Borrmann type 4 gastric cancer, a localized disease can be cured by a radical resection. (Korean J Gastroenterol 2003;41:9-14)
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결구상추 균핵병균(Sclerotinia sclerotioum)에 대한 길항세균의 분리 및 동정
김한우,이광렬,백정우,김현주,박종영,이진우,정순재,문병주,Kim, Han-Woo,Lee, Kwang-Youll,Baek, Jung-Woo,Kim, Hyun-Ju,Park, Jong-Young,Lee, Jin-Woo,Jung, Soon-Je,Moon, Byung-Ju 한국식물병리학회 2004 식물병연구 Vol.10 No.4
결구상추에 심각한 피해를 일으키는 균핵병의 생물학적 방제를 위한 기초연구로서 균핵병원균 S. sclerotioum YR-1 대한 우수 길항세균을 선발하고 동정하였다. 건전 결구상추에서 분리한 세균들 중 균핵병원균의 균사생육저지 효과가 큰 10 균주를 길항세균으로 1차 선발하고 이들 일차 길항세균에 의한 방제효과를 생육실내 포트검정한 결과, A-2, A-7 및 RH-4 균주의 방제가가 각각 73.0%, 85.0%, 80.0%이었으며, 이 중 가장 높은 방제가를 보인 A-7 균주를 우수 길항균으로 최종선발하였다. A-7 균주의 생화학적 특성 및 16S rDNA와 gyrA 염기서열을 분석한 결과 Bacillus amyloliquefaciens로 동정되었으며, B. amyloliquefaciens A-7으로 명명하였다. The fungus genus Sclerotinia contains a number of important plant pathogens. Vegetable growers in our country are probably most familiar with Sclerotinia sclerotiorum, the causes of sclerotinia rot on crisphead lettuce. S. sclerotiorum has a wide host range which can include lettuce as well as crops such as broccoli, cabbage, carrots, celery, beans, peppers, potatoes, stocks, and tomato. Some fungicides, including benomyl, are effective in some crops, but not all. So, we isolated a antagonistic bacteria that are active on sclerotinia rot caused by S. sclerotiorum and that can be used to control it. About 702 strains had been isolated from soil around plant roots in the field. Ten strains showed strong antifungal activity against S. sclerotiorum. In pot test for antagonistic activity, A-7 strain showed high control value against the pathogen when compared with others. The strain was, therefore, selected as a biocontrol candidate against sclerotinia rot and its biochemical properties and 16S rDNA sequence was analyzed. The A-7 strain was highly related to Bacillus subtilis and B. amyloliquefaciens. To confirm precise identification, we had performed gyr A gene sequences analysis. Its sequence had 96% similarity with B. amyloliquefaciens. Consequently, the isolate was identified as B. amyloliquefaciens A-7.
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