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한진안,구본수,이경진,배형섭 대한한방성인병학회 2000 韓方成人病學會誌 Vol.6 No.1
Distal myopathy is a rare muscular disease and Nonaka type is known to be inherited as autosomal recessive trait and to have no specific treatment. Hereby, we report a case of distal myopathy diagnosised by EMG. The clinical symptoms were slowly progressive symmetrical muscle weakness and wasting of all 4 extremities, so the patient could not sustain for herself. After admission, the patient was improved in motor power and general condition with the treatment of Boikyangwie-tang(buyiyangwei-tang), acupuncture and physical exercise.
양릉천-현종 전침치료가 뇌경색환자 및 정상인의 뇌혈류에 미치는 영향 - SPECT와 SPM을 이용한 연구 -
한진안,문상관,정동원,배형섭,박성욱,정우상,박정미,고창남,조기호,김영석,김덕윤 대한한의학회 2006 대한한의학회지 Vol.27 No.3
Objectives: Acupuncture has been specially applied on the rehabilitation after stroke in Asia for thousands of years. It was reported that acupuncture increased cerebral blood supply and stimulated the functional activity of brain nerve cells by using brain image techniques. This study was to evaluate the effect of GB 34-GB 39 electro-acupuncture (EA) on regional cerebral blood flow (rCBF) in stroke patients and normal volunteers using Single Photon Emission Computed Tomography (SPECT). Methods: The study procedure was divided into two part; patients and volunteers study. For patients study, ten ischemic stroke patients(3 males, 7 females, mean age 68.5±8.9 years old) were selected. Baseline brain SPECT was done with triple head gamma camera (MultiSPECT3, Siemens, USA) after intravenous administration of 1,110 MBq of 99mTc-ECD. Fifteen-minute EA at GB 34 and GB 39 were applied on affected limb. The same dose of 99mTc-ECD was injected during the EA, and the second SPECT images were obtained. Using the computer software (ICON 7.1, Siemens, USA), 3 SPECT slices (upper, middle, lower) surrounding the brain lesion were selected and each slice was divided by 10-16 brain regions. Asymmetry indexes (AI) were analyzed in each brain region. We regarded over 10% changes of AI between before and after EA as significance. For volunteers study, 10 healthy human volunteers (5 males, 5 females, mean age 28.1±6 years old) were selected. In the resting state, 99mTc-ECD brain SPECT scans were performed. On the 7th day after the resting examination, 15 minute EA was applied at GB 34 and GB 39 on the right side of the subjects. Immediately after EA, the second SPECT images were obtained with the same manner as the resting state. Significant increases and decreases of rCBF after EA were estimated by comparing their SPECT images with those of the resting state using paired t statistics at every voxel, which were analyzed by statistical parametric mapping with a threshold of p = 0.01, uncorrected (extent threshold: k=100 voxels). Results: In stroke patients, six(75%) of eight had significantly increased perfusion in post-acupunture scans compared to baseline state. In normal volunteers, GB 34-GB 39 EA increased rCBF in both hemisphere including right ventral posterior cingulate(Brodmann area (BA) 23), left superior temporal, anterior transverse temporal(BA 22, 41), left parastriate, peristriate(BA 18, 19), right occipitotemporal, angular(BA 37, 39), left rostral postcentral, caudal postcentral and preparietal(BA 2, 3, 5). However GB 34-GB 39 EA decreased rCBF in right hemisphere including triangular and middle frontal lobes. Conclusions: The results demonstrated that GB 34-GB 39 EA increased cerebral perfusion in ischemic stroke patients also increased rCBF grossly in temporal lobes in normal volunteer. It is also suggested that there may be a correlation between GB meridian and the territory of middle cerebral artery.
중풍환자의 급성요도염에 대하여 단독 한방처방 투여로 치료한 1례
한진안,조기호,김정진,Han, Jin-An,Cho, Ki-Ho,Kim, Jung-Jin 대한한방내과학회 2002 大韓韓方內科學會誌 Vol.23 No.2
Urinary tract infection(UTI) is one of the common complications in stroke patients. As it has negative effect on the recovery of stroke, it should be cured out immediately. But antibiotics might cause some adverse reactions such as diarrhea, eruption, anorexia, nausea and vomiting. so there have been several reports about treating urinary tract infection with Traditional Korean Medication. We treated a 54-year-old male patient with cerebral hemorrhage, who had had neurogenic bladder after stroke and had been urinated by intermittent catheterization. About 10 days later, he could void by himself without catheter, but showing the symptoms of UTI; Voiding pain, hematuria and yellowish pus. The pus culture grew Staphylococcus spp., which was resistant to most of antibiotics except vancomycin and teicoplanin. Based on accompanying symptoms of intermittent dizziness, headache, insomnia, nocturnal sweating, weak pulse, red tongue and urinary problem, we differentiated him as the deficiency of Yin of the Kidney[腎陰虛] and treated with Gagamyookmijihwang-tang (Jia-Jian-Liu-Wei-De- Huang-Tang), which improved his urinary symptoms and other general conditions without any side effect. In next follow-up culture, there was no pathogen. We conclude that Traditional Korean Medicine based on differentiation is useful in the treatment of urinary tract infection.
내측연수경색 환자의 정전가미이진탕(正傳加味二陳湯) 투여(投與) 1례(例)
최요섭,한진안,이경섭,윤상필,Choi, Yo-Sup,Han, Jin-An,Lee, Kyung-Sup,Yun, Sang-Pil 대한한방내과학회 2002 大韓韓方內科學會誌 Vol.23 No.2
Medial medullary infarction is caused by occlusion of vertebral artery or lower basilar artery. In this report, one case had impaired pain and thermal sense over half the body, and complained of dizziness, nausea and vomiting. The other symptoms were slippery pulse(脈滑), pale tongue with whitish coating(舌淡苔白), white face(面白), obesity(體肥) and unchanged skin color(肌色如故). We diagnosed this patient as the Gastrointestinal Phlegm(食痰) and prescribed Jengjengamiyijin-tang (Zhengchuanjiaweierchen-tang). The symptoms of impaired pain and thermal sense, dizziness, nausea, and vomiting were improved. So, we suggest that Jengjengamiyijin-tang (Zhengchuanjiaweierchen-tang) could be effective to the patient with the symptom of the Gastrointestinal Phlegm(食痰)