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마황(麻黃) 약침액(藥鍼液)이 사람 기관지 상피세포의 TARC 분비에 미치는 효과
주유적 ( Yu Shih Chou ),서정철 ( Jung Chul Seo ),임성철 ( Seong Chul Lim ),정태영 ( Tae Young Jung ),한상원 ( Sang Won Han ) 대한경락경혈학회 2005 Korean Journal of Acupuncture Vol.22 No.1
Chemokines are important for the recruitment of leukocytes, which is essential in host defense to the sites of infection. The thymus and activation-regulated chemokine (TARC) is a CC chemokine which potentially plays a role via a paracrine mechanism in the development of allergic respiratory diseases. Objectives: The objective of this study is to investigate the effect of Ephedrae Herba Herbal Acupuncture Solution(EHS) on the secretion of TARC of human bronchial epithelial cell. Methods: Enzyme-linked immunosorbent assay (ELISA) was performed to detect the secretion of TARC. The cytotoxicity was measured by MTT assay. Results: EHS significantly inhibited the secretion of TARC with a dose-dependant manner. The effective dosage did not have the cytotoxicity on human bronchial epithelial cell. Conclusion: Results of our study imply that EHS would play an important role in modulation of TARC in human bronchial epithelial cells by MTT assay.