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Encapsulating peritoneal sclerosis: case series from a university center
( Kyung Euk Hong ),( Ji Hea Bae ),( Yun In Jang ),( Heeyeon Jung ),( Jang Hee Cho ),( Ji Young Choi ),( Chan Duck Kim ),( Yong Lim Kim ),( Sun Hee Park ) 대한내과학회 2013 The Korean Journal of Internal Medicine Vol.28 No.5
Background/Aims: Encapsulating peritoneal sclerosis (EPS) is an often-fatal complication of long-term peritoneal dialysis (PD). We here report the clinical features of EPS in Korean PD patients from a single university center. Methods: The data were collected retrospectively from 606 PD patients at Kyungpook National University Hospital, between August 2001 and August 2011. The diagnosis of EPS was based on clinical signs and symptoms, and confirmed by radiological findings. Results: Eight patients (1.3%, four males) were diagnosed with EPS. The mean age of the patients was 48.5 years (range, 33 to 65). The mean duration of PD was 111.8 months (range, 23 to 186). All patients except for one had three or more episodes of peritonitis. Seven patients were diagnosed with EPS after stopping PD, and only one stayed on PD after initial diagnosis and treatment. Total parenteral nutrition and corticosteroids, in addition to tamoxifen therapy, were used to treat most of the patients, and one patient underwent surgery (adhesiolysis). The overall mortality rate was 50%. Conclusions: EPS is a serious, life-threatening complication in patients on longterm PD. To reduce the incidence and mortality rate of EPS, careful monitoring and early diagnosis is needed.
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