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      • KCI등재

        Magnetic Flux Leakage Image Enhancement using Bidimensional Empirical Mode Decomposition with Wavelet Transform Method in Oil Pipeline Nondestructive Evaluation

        Liang Chen,Jingcheng Li,Yakai Zeng,Yongqiang Chen,Wei Liang 한국자기학회 2019 Journal of Magnetics Vol.24 No.3

        The magnetic flux leakage (MFL) method is the most widely used and cost-effective inspection technique for oil pipeline. However, noise is inevitable in the process of data collection; thus, the image enhancement method can be more intuitive to identify the defects in an oil pipeline MFL inspection. In this paper, the bidimensional empirical mode decomposition (BEMD) method has been used to study oil pipeline MFL images. The MFL image is decomposed into a finite number of two-dimensional intrinsic mode functions (BIMF) and a residual component by the BEMD. The wavelet transform (WT) was used to remove the noise in the BIMF. The image was then reconstructed by retaining the basic information and removing the noise. The results show that the noise is effectively removed and the detail of the MFL image is well preserved. Thus, the BEMD with WT method for oil pipeline MFL image enhancement is better than the mean filtering method and the WT method.

      • Lymph Node Ratio is an Independent Prognostic Factor in Node Positive Rectal Cancer Patients Treated with Preoperative Chemoradiotherapy Followed by Curative Resection

        Zeng, Wei-Gen,Zhou, Zhi-Xiang,Wang, Zheng,Liang, Jian-Wei,Hou, Hui-Rong,Zhou, Hai-Tao,Zhang, Xing-Mao,Hu, Jun-Jie Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.13

        Background: The lymph node ratio (LNR) has been shown to be an important prognostic factor for colorectal cancer. However, studies focusing on the prognostic impact of LNR in rectal cancer patients who received neoadjuvant chemoradiotherapy (CRT) followed by curative resection have been limited. The aim of this study was to investigate LNR in rectal cancer patients who received neoadjuvant chemoradiotherapy (CRT) followed by curative resection. Materials and Methods: A total of 131 consecutive rectal cancer patients who underwent neoadjuvant CRT and total mesorectal excision were included in this study. Patients were divided into two groups according to the LNR (${\leq}0.2$ [n=86], >0.2 [n=45]) to evaluate the prognostic effect on overall survival (OS) and disease-free survival (DFS). Results: The median number of retrieved and metastatic lymph node (LN) was 14 (range 1-48) and 2 (range 1-10), respectively. The median LNR was 0.154 (range 0.04-1.0). In multivariate analysis, LNR was shown to be an independent prognostic factor for both overall survival (hazard ratio[HR]=3.778; 95% confidence interval [CI] 1.741-8.198; p=0.001) and disease-free survival (HR=3.637; 95%CI 1.838-7.195; p<0.001). Increased LNR was significantly associated with worse OS and DFS in patients with <12 harvested LNs, and as well as in those ${\geq}12$ harvested LNs (p<0.05). In addition, LNR had a prognostic impact on both OS and DFS in patients with N1 staging (p<0.001). Conclusions: LNR is an independent prognostic factor in ypN-positive rectal cancer patients, both in patients with <12 harvested LNs, and as well as in those ${\geq}12$ harvested LNs. LNR provides better prognostic value than pN staging. Therefore, it should be used as an additional prognostic indicator in ypN-positive rectal cancer patients.

      • KCI등재

        Subspace Identification for Fractional Order Hammerstein Systems Based on Instrumental Variables

        Zeng Liao,Zhuting Zhu,Shu Liang,Cheng Peng,Yong Wang 제어·로봇·시스템학회 2012 International Journal of Control, Automation, and Vol.10 No.5

        This paper focuses on time-domain identification issues of multi-input multi-output (MIMO) fractional order Hammerstein systems which are the extension of traditional Hammerstein type models by allowing linear part to be fractional order systems. The principal component analysis (PCA) method in subspace family is extended to identify coefficient matrixes of fractional order systems. Singular value decomposition (SVD) is utilized to estimate the unknown parameters of nonlinear part of system directly. A proper instrumental variable is chosen to eliminate the bias of identification results. Numerical simulation validates the proposed method.

      • The Noise Monitoring System and Automatic Correction Algorithm

        Zeng Huapu,Li Yuting,Xu Huiyu,Pu Yunming,Qiao feng,Liang jun 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.9

        For the improvement of living environment, there are more needs of the real time and online automatic noise monitoring system installed in many urban areas. In this project, the principle of noise audio frequency processing and coding algorithm was researched, including Discrete Cosine Transform and Wavelet Transform. The noise monitoring system solved the synchronous problem between the audio data and noise decibel, the special storage format separated the audio data which can be located in probability, and the audio data across segments to be played continually. The design of double-layer structure and isolating solved the problem of heat dissipating, waterproof and dustproof. In the experimental testing of the noise monitoring system, the noise decibel was affected by temperature and differential pressure, for improving its precision, the linear regression model is applied in the calculation of noise decibel. The least estimate method was used to calculate the residual for the automatic correction of the noise monitoring, and increase the accuracy of noise monitoring.

      • KCI등재

        THEORETICAL STUDY OF THE ADSORPTION AND DIFFUSION OF OXYGEN ATOM ON O-TERMINATED ZnO (000 ? 1) SURFACE

        LIANG QIAO,YI ZENG,CHAOQUN QU,XIAOYING HU,LIJUN SONG,YONGMING SUI 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.1

        The adsorption and difusion of oxygen atom on the O-terminated ZnO ð 000?1 Þ surface havebeen systematically investigated based on ¯rst-principles density functional theory. The resultsshow that the surface relaxation of the ZnO ð 000?1 Þ surface is signi¯cant. In the view of themaximization of the adsorption energy, the preferred site for the adsorption of oxygen atom is thetop-O site above the oxygen atom of the ¯rst Zn – O bilayer. There is chemical bond formedbetween the adsorbed oxygen atom and the oxygen atom on the surface, which will result in theredistribution of the charges. The charges transfer from the ZnO surface to the adsorbed oxygenatom, which will heighten the surface potential of ZnO surface and increase the surface workfunction. Moreover, the di®usion of the oxygen atom on the ZnO surface has also been investi-gated, and the potential barriers of the difusion have been identi¯ed to reveal the adsorptionstability

      • KCI등재

        Assessment of clinical competency among TCM medical students using standardized patients of traditional Chinese medicine: A 5-year prospective randomized study

        Zeng Jinhao,Liang Shuang,Zhang Xiaotong,Yan Ran,Chen Chongli,Wen Lijuan,Xia Ting,Li Wenyuan,Lu Bingqing,Nian Qing,Yang Han,Guo Jing 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.2

        Background: Some Western medicine schools in China established standardized patient (SP) programs for medical education. However, SP programs are rarely applied to the education of traditional Chinese medicine (TCM). In this study, we evaluated the effectiveness of using standardized patient traditional Chinese medicine (SP-TCM) to improve clinical competency among TCM medical students. Methods: This study was a prospective, 2-group, parallel-training randomized trial over the course of 5 years. Data were collected from September 2016 to December 2020. Participants in each year were randomly allocated into the traditional-method training group or the SP-TCM training group (1:1) for a 3-month curriculum. Measurement of clinical competency among all trainees was based on a standardized examination composed of scores of medical record documentation, scores of TCM syndrome differentiation and therapeutic regimen, and checklist assessment from both SP-TCMs and TCM professionals. Feedback was collected using semi-constructive questionnaires from both groups. Results: Compared with those assigned to traditional-method training, those assigned to SP-TCM training demonstrated significantly greater post-training improvement in medical record documentation and TCM syndrome differentiation and therapeutic regimen. Moreover, SP-TCM trainees outscored those assigned to traditional training in the assessment for encounter performance given by independent SP-TCMs and TCM professionals. The SP-TCM method gained higher satisfaction of training efficacy and test performance than the traditional method. Conclusion: This SP-TCM program demonstrated great benefits for improving clinical competency among TCM medical students.

      • KCI등재

        A Novel 3-D Imaging Configuration Exploiting Synthetic Aperture Ladar

        Liang Guo,Yinli Huang,Xiaozhen Li,Xiaodong Zeng,Yu Tang,Mengdao Xing 한국광학회 2017 Current Optics and Photonics Vol.1 No.6

        Traditional three-dimensional (3-D) laser imaging systems are based on real aperture imaging technology,whose resolution decreases as the range increases. In this paper, we develop a novel 3-D imaging techniquebased on the synthetic aperture technology in which the imaging resolution is significantly improved anddoes not degrade with the increase of the range. We consider an imaging laser radar (ladar) system usingthe floodlight transmitting mode and multi-beam receiving mode. High 3-D imaging resolutions areachieved by matched filtering the linear frequency modulated (LFM) signals respectively in range, syntheticaperture along-track, and the real aperture across-track. In this paper, a novel 3-D imaging signal modelis given first. Because of the motion during the transmission of a sweep, the Doppler shift induced bythe continuous motion is taken into account. And then, a proper algorithm for the 3-D imaging geometryis given. Finally, simulation results validate the effectiveness of the proposed technique.

      • Gefitinib Alone or with Concomitant Whole Brain Radiotherapy for Patients with Brain Metastasis from Non-small-cell Lung Cancer: A Retrospective Study

        Zeng, Yin-Duo,Zhang, Li,Liao, Hai,Liang, Ying,Xu, Fei,Liu, Jun-Ling,Dinglin, Xiao-Xiao,Chen, Li-Kun Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.3

        Background: Gefitinib, a tyrosine kinase inhibitor (TKI) of epidermal growth factor receptor (EGFR), is used both as a single drug and concurrently with whole brain radiotherapy (WBRT) the standard treatment for brain metastases (BM), and is reported to be effective in a few small studies of patients with BM from non-small-cell lung cancer (NSCLC). However, no study has compared the two treatment modalities. This retrospective analysis was conducted to compare the efficacy of gefitinib alone with gefitinib plus concomitant WBRT in treatment of BM from NSCLC. Methods: We retrospectively reviewed 90 patients with BM from NSCLC who received gefitinib alone (250mg/day, gefitinib group) or with concomitant WBRT (40Gy/20f/4w, gefitinib-WBRT group) between September 2005 and September 2009 at Sun Yat-Sen University Cancer Center. Forty-five patients were in each group. Results: The objective response rate of BM was significantly higher in gefitinib-WBRT group (64.4%) compared with gefitinib group (26.7%, P<0.001). The disease control rate of BM was 71.1% in gefitinib-WBRT group and 42.2% in gefitinib group (P=0.006). The median time to progression of BM was 10.6 months in gefitinib-WBRT group and 6.57 months in gefitinib group (P<0.001). The median overall survival(OS) of gefitinib-WBRT and gefitinib alone group was 23.40 months and 14.83 months, respectively (HR, 0.432, P=0.002). Conclusion: Gefitinib plus concomitant WBRT had higher response rate of BM and significant improvement in OS compared with gefitinib alone in treatment of BM from NSCLC.

      • SCIESCOPUSKCI등재

        Adenoviral Vector Mediates High Expression Levels of Human Lactoferrin in the Milk of Rabbits

        ( Zeng Sheng Han ),( Qing Wang Li ),( Zhi Ying Zhang ),( Yong Sheng Yu ),( Bo Xiao ),( Shu Yun Wu ),( Zhong Liang Jiang ),( Hong Wei Zhao ),( Rui Zhao ),( Jian Li ) 한국미생물 · 생명공학회 2008 Journal of microbiology and biotechnology Vol.18 No.1

        The limitations in current technology for generating transgenic animals, such as the time and the expense, hampered its extensive use in recombinant protein production for therapeutic purpose. In this report, we present a simple and less expensive alternative by directly infusing a recombinant adenovirus vector carrying human lactoferrin cDNA into rabbit mammary glands. The milk serum was collected from the infected mammary gland 48 h post-infection and subjected to a 10% SDS-PAGE and Western blotting. An 80-kDa protein was visualized after viral vector infection. With this method, we obtained a high level of expressed human lactoferrin of up to 2.3 mg/ml in the milk. Taken together, the method is useful for the transient high-level expression recombinant proteins, and the approach established here is probably one of the most economical and efficient ways for large-scale production of recombinant proteins of biopharmaceutical interest.

      • Induction Chemotherapy Followed by Concurrent Chemoradiotherapy Versus Concurrent Chemoradiotherapy with or without Adjuvant Chemotherapy for Locoregionally Advanced Nasopharyngeal Carcinoma: Meta-analysis of 1,096 Patients from 11 Randomized Controlled

        Liang, Zhong-Guo,Zhu, Xiao-Dong,Tan, Ai-Hua,Jiang, Yan-Ming,Qu, Song,Su, Fang,Xu, Guo-Zeng Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

        Purpose: To evaluate the efficacy and toxicity of induction chemotherapy followed by concurrent chemoradiotherapy (the treatment group) versus concurrent chemoradiotherapy with or without adjuvant chemotherapy (the control group) for locoregionally advanced nasopharyngeal carcinoma. Methods: The search strategy included Pubmed, Embase, the Cochrane Library, China National Knowledge Internet Web, Chinese Biomedical Database and Wanfang Database. We also searched reference lists of articles and the volumes of abstracts of scientific meetings. All randomized controlled trials were included for a meta-analysis performed with RevMan 5.1.0. The Grading of Recommendations Assessment, Development, and Evaluation system (GRADE) was used to rate the level of evidence. Results: Eleven studies were included. Risk ratios of 0.99 (95%CI 0.72-1.36), 0.37 (95%CI 0.20-0.69), 1.08 (95%CI 0.84-1.38), 0.98 (95%CI 0.75-1.27) were observed for 3 years overall survival, 3 years progression-free survival, 2 years loco-regional failure-free survival and 2 years distant metastasis failure-free survival. There were no treatment-related deaths in either group in the 11 studies. Risk ratios of 1.90 (95%CI 1.24-2.92), 2.67 (95%CI 0.64-11.1), 1.04 (95%CI 0.79-1.37), 0.98 (95%CI 0.27-3.52) were found for grade 3-4 leukopenia, grade 3-4 thrombocytopenia, grade 3-4 mucous membrane, and grade 3-4 hepatic hematologic and gastrointestinal toxicity, the most significant toxicities for patients. Conclusion: Compared with the control group, induction chemotherapy followed by concurrent chemoradiotherapy was well tolerated but could not significantly improve prognosis in terms of overall survival, loco-regional failure-free survival or distant metastasis failure-free survival.

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