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Yoshinori Sakurai,Hiroki Tanaka,Takushi Takata,Nozomi Fujimoto,Minoru Suzuki,Shinichiro Masunaga,Yuko Kinashi,Natsuko Kondo,Masaru Narabayashi,Yosuke Nakagawa,Tsubasa Watanabe,Koji Ono,Akira Maruhashi 한국물리학회 2015 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.67 No.1
At the Kyoto University Research Reactor Institute (KURRI), a clinical study of boron neutron capture therapy (BNCT) using a neutron irradiation facility installed at the research nuclear reactor has been regularly performed since February 1990. As of November 2014, 510 clinical irradiations were carried out using the reactor-based system. The world’s first accelerator-based neutron irradiation system for BNCT clinical irradiation was completed at this institute in early 2009, and the clinical trial using this system was started in 2012. A shift of BCNT from special particle therapy to a general one is now in progress. To promote and support this shift, improvements to the irradiation system, as well as its preparation, and improvements in the physical engineering and the medical physics processes, such as dosimetry systems and quality assurance programs, must be considered. The recent advances in BNCT at KURRI are reported here with a focus on physical engineering and medical physics topics.
Suwen Yang,Tanji Hoshi,Motoyuki Yuasa,Naoko Nakayama,Chika Takagi,Naoko Inoue,Naoko Sakurai,Yoshinori Fujiwara 서울시립대학교 도시과학연구원 2012 도시과학국제저널 Vol.16 No.1
This study aimed to reveal the causal relationships of dietary and lifestyle habits with socio-economic status (SES) and three health-related factors (physical,mental and social health) in elderly urban dwellers in Japan. All the elderly urban dwellers aged 65 years or more in an urban area of Tokyo were surveyed using a self-administered questionnaire in September 2001. There were 13,195 respondents with a response rate of 80.2%. And then, two follow-up surveys were conducted in 2004 and 2007, respectively. Finally, 8162 respondents were included as analysis subjects. Data analysis was performed using factor analysis and structural equation modelling (SEM). As a result of an exploratory factor analysis, three latent variables (‘dietary and lifestyle habits in 2004’, ‘SES in 2001’and ‘three health-related factors in 2001’) were defined and applied in the SEM. From the best-fit models, dietary and lifestyle habits in 2004 were well explained by SES and three health-related factors in 2001 (R2 ¼ 0.44 for elderly men and R2 ¼ 0.61 for elderly women). The results showed that dietary and lifestyle habits in 2004 were not only directly affected by SES and the three health-related factors in 2001, but also indirectly by SES via the three health-related factors. Moreover,the causal relationships between the three latent variables depended on sex and age. In conclusion, SES as a basic determinant – enough income, high education level and good physical, mental and social health – favoured both directly and indirectly the practice of healthy or desirable lifestyle habits of the elderly late in life. It will be necessary to construct a model with higher external validity in a future study.