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RISS 인기검색어
- 검색키워드
- 저자 : Yanmei Gao (검색결과 3 건)
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Yanmei Gao,Liang Fan,Weipeng Yang,Lu Shi,Dan Zhou,Ming Wang 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.45 No.3
The mechanical behaviors of the prefabricated steel-concrete composite beams are usually affected by the strength and the number of shear studs. Furthermore, the discrete degree of the arrangement for shear stud clusters, being defined as the clustering degree of shear stud λ in this paper, is an important factor for the mechanical properties of composite beams, even if the shear connection degree is unchanged. This paper uses an experimental and calculation method to investigate the influence of λ on the mechanical behavior of the composite beam. Five specimens (with different λ but having the same shear connection degree) of prefabricated composite beams are designed to study the ultimate supporting capacity, deformation, slip and shearing stiffness of composite beams. Experimental results are compared with the conventional slip calculation method (based on the influence of λ) of prefabricated composite beams. The results showed that the stiffness in the elastoplastic stage is reduced when λ is greater than 0.333, while the supporting capacity of beams has little affected by the change in λ. The slip distribution along the beam length tends to be zig-zagged due to the clustering of studs, and the slip difference increases with the increase of λ.
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Yinhui Wang,Yanmei Gao,Zhixiang Zhou,Dong Liu 국제구조공학회 2016 Steel and Composite Structures, An International J Vol.21 No.5
To avoid the cracks of cast-in-place concrete in shear pockets and seams in the traditional composite beam with precast decks, this paper proposed a new type of prefabricated steel truss-concrete composite beam (ab. PSTC beam) with pre-embedded shear studs (ab. PSS connector). To study the initial cracking load of concrete deck, the development and distribution laws of the cracks, 3 PSTC beams were tested under hogging moment. And the crack behavior of the deck was compared with traditional precast composite beam, which was assembled by shear pockets and cast-in-place joints. Results show that: (i) the initial crack appears on the deck, thus avoid the appearance of the cracks in the traditional shear pockets; (ii) the crack of the seam appears later than that of the deck, which verifies the reliability of epoxy cement mortar seam, thus solves the complex structure and easily crack behavior of the traditional cast-in-place joints; (iii) the development and the distribution laws of the cracks in PSTC beam are different from the conventional composite beam. Therefore, in the deduction of crack calculation theory, all the above factors should be considered.
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Vaginal Microbiome Dysbiosis is Associated with the Different Cervical Disease Status
Ma Yingying,Li Yanpeng,Liu Yanmei,Cao Le,Han Xiao,Gao Shujun,Zhang Chiyu 한국미생물학회 2023 The journal of microbiology Vol.61 No.4
Vaginal microbiome composition was demonstrated to be associated with cervical disease. The colonization characteristics of vaginal microbes and their association with the different cervical disease status, especially cervical cancer (CC), are rarely investigated. In this cross-sectional study, we characterized the vaginal microbiome of women with different status of cervical diseases, including 22 NV + (normal tissue with HPV infection), low-grade squamous intraepithelial lesion (LSIL, n = 45), high-grade squamous intraepithelial lesion (HSIL, n = 36) and CC (n = 27) using bacterial 16S DNA sequencing. Thirty HPV-negative women with normal tissue were used as the control group. We found that higher diversity of microbiome with gradual depletion of Lactobacillus, especially L. crispatus, was associated with the severity of cervical disease. High-risk HPV16 infection was associated with higher microbiome diversity and depletion of Lactobacillus in high-grade cervical diseases (i.e. HSIL and CC). The CC group was characterized by higher levels of Fannyhessea vaginae, Prevotella, Bacteroides, Finegoldia, Vibrio, Veillonella, Peptostreptococcus, and Dialister. Co-occurrence network analyses showed that negative correlations were exclusively observed between Lactobacillus and other bacteria, and almost all non-Lactobacillus bacteria were positively correlated with each other. In particular, the most diverse and complex co-occurrence network of vaginal bacteria, as well as a complete loss of L. crispatus, was observed in women with CC. Logistic regression model identified HPV16 and Lactobacillus as significant risk and protective factors for CC, respectively. These results suggest that specific Lactobacillus species (e.g. L. crispatus and L. iners) can be used as important markers to target prevention measures prioritizing HPV16-infected women and other hrHPV-infected women for test, vaccination and treat initiatives.
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