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Structure and magnetic properties of CrN thin films on La0.67Sr0.33MnO3
Zhongpo Zhou,Dingbo Zhang,Haiying Wang,Tianxing Wang,Zhansheng Lu,Zongxian Yang,Zhiwei Ai,Hao Wu,Chang Liu 한국물리학회 2018 Current Applied Physics Vol.18 No.11
High crystalline quality CrN thin films have been grown on La0.67Sr0.33MnO3 (LSMO) templates by molecular beam epitaxy. The structure and magnetic properties of CrN/LSMO heterojunctions are investigated combining with the experiments and the first-principles simulation. The Nėel temperature of the CrN/LSMO samples is found to be 281 K and the saturation magnetization of CrN/LSMO increases compared to that of LSMO templates. The magnetic property of CrN/LSMO heterostructures mainly comes from Cr atoms of (001) CrN and Mn atoms of (001) LSMO. The (001) LSMO induces and couples the spin of the CrN sublattice at CrN/LSMO interface.
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Immunomodulatory effects of Clostridium butyricum on human enterocyte-like HT-29 cells
Gao Quanxin,Wang Jinbo,Qi Lili,Wu Tianxing,Xia Tingting 한국통합생물학회 2013 Animal cells and systems Vol.17 No.2
Oral administration of Clostridium butyricum as probiotics is increasingly gaining importance in the treatment of intestinal inflammations and improvement of animal performance. The mechanisms of host cell receptor recognition of C. butyricum and downstream immune signaling pathways leading to this beneficial event, however, remain unclear. In this study, C. butyricum was investigated for its capability to influence the innate immune response of HT-29 cells to explore its mechanism of action. Our data showed that C. butyricum was able to stimulate toll-like receptor 2 (TLR2) production at mRNA level; however, TLR4, TLR5, TLR9, and myeloid differentiation primary response protein 88 (MyD88) transcription levels remain unaltered. The nuclear factor kB (NF-kB), interleukin-8 (IL-8), and tumor necrosis factor alpha (TNF-a) levels in response to C. butyricum were significantly increased, indicating that HT-29 cells were sensitised by C. butyricum. It is the first time that our findings have showed the specific signaling pathways in HT-29 cells stimulated by C. butyricum, which, at least in part, can help to explain the beneficial properties of C. butyricum.
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