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LINEAR VERSUS NON-LINEAR PREDICTABILITY OF EQUITY PRICES: AN EMPIRICAL INVESTIGATION
Tsoukalas Dimitrios People&Global Business Association 2004 Global Business and Finance Review Vol.9 No.2
The analysis of this study is twofold: 1) Using A non-linear test (the Hinich test), it provides evidence of non-linear dynamics in stock prices in the American market from January 1955 to December 2002. 2) Utilizing non-linear regression models, the Multiple Adaptive Regression Splines (MARS) and Ⅱ-Splines, the study examines the relationship between stock prices and their fundamentals. Non-linear results are compared with linear. The predictive ability of the non-linear models outperforms the linear. As a result, the study suggests that non-linear models should be considered for the analysis of stock prices.
AN IMPULSE RESPONSE FUNCTIONS AND VARIANCE DECOMPOSITIONS ANALYSIS OF INTERNATIONAL EQUITIES
Dimitrios Tsoukalas People&Global Business Association 2001 Global Business and Finance Review Vol.6 No.1
We investigate the components of equity returns across three major national stock markets using explanatory variables, dividend-price ratios and dividend growth rates. The analysis employs the structural Vector Autoregressive Approach (SVAR) to a data set for the period of January 1955 to December 1999. In general, we conclude that dynamic stock return behavior is accounted for primarily by innovations in dividend-price ratios. In all markets stock returns are characterized by the same temporary mean reverting components. These findings, however, cannot be viewed as evidence against market efficiency. We consider the "information" hypothesis of dividends to justify the temporary mean reverting components of stock returns.
Kouloulias, Vassilis,Tolia, Maria,Tsoukalas, Nikolaos,Papaloucas, Christos,Pistevou-Gombaki, Kyriaki,Zygogianni, Anna,Mystakidou, Kyriaki,Kouvaris, John,Papaloucas, Marios,Psyrri, Amanda,Kyrgias, Geor Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.1
Background: The aim of the study was to determine whether the expression of baseline phosphorus (P) and magnesium (Mg) levels were prognostic in terms of stage and overall survival (OS) in newly diagnosed non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) patients. Materials and Methods: Retrospectively, 130 patients were selected at the time of diagnosis oflung cancer (100 with NSCLC and 30 with SCLC), before the initialization of any chemo-radiotherapy. The median age was 67 (range 29-92). IA, IB, IIA, IIB, IIIA, IIIB and IV stages were present in 3, 4, 19, 6, 25, 8, and 65 patients, respectively. After centrifugation, the levels of serum P and Mg were measured using the nephelometric method/ photometry and evaluated before any type of treatment. Results: Higher than normal levels of P were found in 127/130 patients, while only four patients had elevated Mg serum values. In terms of Spearman test, higher P serum values correlated with either stage (rho=- 0.334, p<0.001) or OS (rho=-0.212, p=0.016). Additionally, a significant negative correlation of Mg serum levels was found with stage of disease (rho=-0.135, P=0.042). On multivariate cox-regression survival analysis, only stage (p<0.01), performance status (p<0.01) and P serum (p=0.045) showed a significant prognostic value. Conclusions: Our study indicated that pre-treatment P serum levels in lung cancer patients are higher than the normal range. Moreover, P and Mg serum levels are predictive of stage of disease. Along with stage and performance status, the P serum levels had also a significant impact on survival. This information may be important for stratifying patients to specific treatment protocols or intensifying their therapies. However, larger series are now needed to confirm our results.
Tzortzis Nomikos,Katerina Gioti,Magafoula Tsoukala,Roxane Tenta 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.10
Pumpkin seed is a rich source of polyphenols and other bioactive compounds that may act as chemopreventive agents against cancer. In this study, five different extracts of pumpkin seeds were evaluated for their ability to affect proliferation and autophagy on PC-3 prostate cancer cells. All extracts (water [W], methanolic, acetone, ethylacetate, and polar lipid [PL]) inhibited cell proliferation in a dose-dependent manner. Treatment of cells with the PL extract increased cell distribution in the S phase, whereas PL and W extracts induced autophagy significantly. Moreover, PL extract induced a remarkable increase of glutathione and oxidized glutathione levels, whereas nitrite and hydrogen peroxide levels were not altered. In conclusion, pumpkin seed extracts affect PC-3 cell viability, oxidative parameters, and autophagic mechanism, thus demonstrating their potential pharmacological use.