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Remineralizing Agents: A Comprehensive Review
Rakesh Mittal,Nikhil Relhan,Tanya Tangri 대한예방치과학회 2017 International Journal of Clinical Preventive Denti Vol.13 No.1
Remineralizing agents are the most desirable means of early enamel caries management. There is a scope for such agents as they prevent the progression of white spot lesions and reverse the process of demineralization. This need has redirected research to develop novel preventive agents that can act as an adjunct to fluoride or independent of it.
Meenu G Singla,Nikhil Relhan,Tanya Tangri 대한예방치과학회 2017 International Journal of Clinical Preventive Denti Vol.13 No.2
Objective: To evaluate the remineralization potential of various commercially available remineralizing agents on artificially produced enamel lesions. Methods: Twenty five human molar teeth extracted for periodontal reasons were collected for this study. Specimens were divided into various groups according to the remineralizing agent used, G1- Colgate Prevident, G2- GC Tooth Mousse, G3- GC Tooth Mousse Plus, G4- Clinpro and G5- SHY-NM Novamin. The baseline surface microhardness (SMH) was measured for all the specimens using the vickersmicrohardness testing machine. Artificial enamel lesions were created by inserting the specimens in demineralizing solution for 96 h. SMH of demineralized specimens was evaluated. Following which 10 days of pH-cycling regimen was carried out and then SMH of remineralized specimens was evaluated. Statistical analysiswas done using Friedman test with Wilcoxon signed rank test for intra group comparison and Kruskal Wallis test with Mann Whitney U test for inter group comparison. p<0.0001 was considered to be significant. Results: Regain in SMH was higher in Clinpro group as compared to Prevident group. Regain in SMH in Clinprogroup & Previdentgroupwas significantly higherthan Novamin group, which was significantly higher than GC Tooth Mousse plus group, which was further significantly higher than GC Tooth Mousse group. Conclusion: All remineralizing pastes used in this study could effectively remineralize the artificially produced early enamel lesions; however, none of them could regain the surface microhardness to the level found at baseline. Clinpro showed best remineralizing efficacy among all test groups.