http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Sung Ui Jung(정성의) (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
Sung Ui Jung(정성의),Kwang Kuk Park(박광국),Song I Yang(양송이),Hee Kyung Jang(장희경),Hee Kyung Jang(신연명) 대한종양외과학회 2014 Korean Journal of Clinical Oncology Vol.10 No.1
Purpose: Mutations in the p53 gene and accumulation of p53 protein are the most common genetic events in gastric carcinomas. This study evaluates the association of p53 gene expression with clinicopathologic findings and prognosis of gastric cancer patients who underwent curative resection. Methods: Retrospective analysis was performed on 236 consecutive patients with gastric cancer who underwent surgery at the Kosin University Gospel Hospital between December 2011 and September 2012. Nuclear p53 expression was detected by immunohistochemistry. Results: p53 expression was detected in 213 patients (90.3%). There was no significant association between positivity for p53 and clinicopathological features. Expression of p53 (P<0.001), tumour, node, metastasis (TNM) stage (P<0.001), T stage (P<0.001), N stage (P<0.001), Lauren classification (P=0.016), neural invasion (P=0.001), lymphatic invasion (P<0.001), vascular invasion (P<0.001), and recurrence (P<0.001) were identified as independent risk factors for overall survival (OS) in univariate analysis. However, on multivariate regression analysis, there was no statistically significant association with OS. Conclusion: In this study, there was no correlation between expression of p53 and clinicopathological features. Although p53 expression was identified as a risk factor for OS in univariate analysis, it had no statistical significance on multivariate regression analysis.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
