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- 저자 : SuYeonIm (검색결과 5 건)
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SuYeonIm,SeonHyeCho,JeongHyoHwang,SeungJinLee 대한약학회 2003 Archives of Pharmacal Research Vol.26 No.1
Drug releasing porous poly(e-caprolactone) (PCL)-chitosan matrices were fabricated for bone regenerative therapy. Porous matrices made of biodegradable polymers have been playing a crucial role as bone substitutes and as tissue-engineered scaffolds in bone regenerative therapy. The matrices provided mechanical support for the developing tissue and enhanced tissue formation by releasing active agent in controlled manner. Chitosan was employed to enhance hydrophilicity and biocompatibility of the PCL matrices. PDGF-BB was incorporated into PCLchitosan matrices to induce enhanced bone regeneration efficacy. PCL-chitosan matrices retained a porous structure with a 100-200 mm pore diameter that was suitable for cellular migration and osteoid ingrowth. NaHCO3 as a porogen was incorporated 5% ratio to polymer weight to form highly porous scaffolds. PDGF-BB was released from PCL-chitosan matrices maintaining therapeutic concentration for 4 week. High osteoblasts attachment level and proliferation was observed from PCL-chitosan matrices. Scanning electron microscopic examination indicated that cultured osteoblasts showed round form and spread pseudopods after 1 day and showed broad cytoplasmic extension after 14 days. PCL-chitosan matrices promoted bone regeneration and PDGF-BB loaded matrices obtained enhanced bone formation in rat calvarial defect. These results suggested that the PDGF-BB releasing PCL-chitosan porous matrices may be potentially used as tissue engineering scaffolds or bone substitutes with high bone regenerative efficacy.
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Information Status and Prosodic Prominence as Perceived by Korean Learners of English
Suyeon Im 서울대학교 언어교육원 2019 語學硏究 Vol.55 No.2
This study investigates the relationship between information status and prosodic prominence perceived by Korean learners of the English language, compared to English native speakers, in a complete public speech. Both groups of speakers were asked to mark words that they perceived as being prominent, while listening to a speech in real time. The information status of a word was annotated as a function of referential and lexical information, as well as focus. The results show that Korean native speakers perceive prosodic prominence in a similar manner to that of English native speakers. Both groups are more likely to perceive prominence for new or focused words than for given or non-focused words. The two groups, however, differ in that Korean native speakers tend to more frequently perceive prominence for words carrying lexical information than English native speakers. This bias seems to be influenced by parts-of-speech, in alignment with the findings of previous studies.
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Prosody Perception on Spontaneous English by Korean Learners of English and Native English Speakers
Suyeon Im 서울대학교 언어교육원 2012 語學硏究 Vol.48 No.3
The present study aims to look at whether Korean English learners’ prosody perception differed from those of native English speakers on the spontaneous English speech. Findings from the study revealed that the Korean English learners significantly differed from the native English speakers in the judgment of prominence while there was no significant group difference in the judgment of boundaries. Among three groups of Korean English learners, the significant group difference was not found in the judgment of prominence and boundaries despite their different English speaking proficiency levels and lengths of residence. The word type (i.e., content word and function word) and boundaries (i.e., intermediate phrase and intonational phrase) appeared to play an important role on the perception of English prosody by the Korean English learners. Also, Korean L1 transfer seemed to have an effect on the perception of prominence and boundaries by the Korean subjects. The results of the study contribute to an understanding of Korean English learners’ perception and of English prosody in a second language. Practical suggestions for future research were also identified.
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Word class information in perception of prosodic prominence by Korean learners of English
Suyeon Im 한국음성학회 2019 말소리와 음성과학 Vol.11 No.4
This study aims to investigate how prosodic prominence is perceived in relation to word class information (or parts-of-speech) by Korean learners of English compared with native English speakers in public speech. Two groups, Korean learners of English and native English speakers, were asked to judge words perceived as prominent simultaneously while listening to a speech. Parts-of-speech and three acoustic cues (i.e., max F0, mean phone duration, and mean intensity) were analyzed for each word in the speech. The results showed that content words tended to be higher in pitch and longer in duration than function words. Both groups of listeners rated prominence on content words more frequently than on function words. This tendency, however, was significantly greater for Korean learners of English than for native English speakers. Among the parts-of-speech of the content words, Korean learners of English were more likely than native English speakers to judge nouns and verbs as prominent. This study presents evidence that Korean learners of English consider most, if not all, content words as landing locations of prosodic prominence, in alignment with the previous study on the production of prominence.
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