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RISS 인기검색어
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- 저자 : Shaofei Wu (검색결과 3 건)
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Shaofei Ren,Wencheng Liu,Ying Song,Hang Geng,Fangguang Wu 대한조선학회 2019 International Journal of Naval Architecture and Oc Vol.11 No.1
Interlocked armor layers of unbonded flexible risers may crush when risers are being launched. In order to predict the behavior of interlocked armor layers, they are usually simplified as rings with geometric and contact nonlinearity ignored in the open-literature. However, the equivalent thickness of the interlocked armor layer has not been addressed yet. In the present paper, a geometric coefficient g is introduced to the equivalent stiffness method, and a linear relationship between g and geometric parameters of interlocked armor layers is validated by analytical and finite element models. Radial stiffness and equivalent thickness of interlocked armor layers are compared with experiments and different equivalent methods, which show that the present method has a higher accuracy. Furthermore, hoop stress distribution of interlocked armor layer under crushing is predicted, which indicates the interlocked armor layer can be divided into two compression and two expansion zones by four symmetrically distributed singular points.
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Ren, Shaofei,Liu, Wencheng,Song, Ying,Geng, Hang,Wu, Fangguang The Society of Naval Architects of Korea 2019 International Journal of Naval Architecture and Oc Vol.11 No.1
Interlocked armor layers of unbonded flexible risers may crush when risers are being launched. In order to predict the behavior of interlocked armor layers, they are usually simplified as rings with geometric and contact nonlinearity ignored in the open-literature. However, the equivalent thickness of the interlocked armor layer has not been addressed yet. In the present paper, a geometric coefficient ${\gamma}$ is introduced to the equivalent stiffness method, and a linear relationship between ${\gamma}$ and geometric parameters of interlocked armor layers is validated by analytical and finite element models. Radial stiffness and equivalent thickness of interlocked armor layers are compared with experiments and different equivalent methods, which show that the present method has a higher accuracy. Furthermore, hoop stress distribution of interlocked armor layer under crushing is predicted, which indicates the interlocked armor layer can be divided into two compression and two expansion zones by four symmetrically distributed singular points.
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Jiayin Fu,Qiongjun Zhu,Zhezhe Chen,Jing Zhao,Shaofei Wu,Meng Zhao,Shihui Xu,Dongwu Lai,Guosheng Fu,Wenbin Zhang 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
Background Bioresorbable stents are designed to provide temporary mechanical support to the coronary arteries and then slowly degrade in vivo to avoid chronic inflammation. Zinc (Zn) is a promising material for bioresorbable stents; However, it can cause inflammation and neointimal formation after being implanted into blood vessels. Methods To improve biocompatibility of Zn, we first coated it with polydopamine (PDA), followed by immobilization of endothelial vascular growth factor (VEGF) onto the PDA coatings. Adhesion, proliferation, and phenotype maintenance of endothelial cells (ECs) on the coated Zn were evaluated in vitro. Then, a wire aortic implantation model in rats mimicking endovascular stent implantation in humans was used to assess vascular responses to the coated Zn wires in vivo. Thrombosis in aortas post Zn wire implantation, degradation of Zn wires in vivo, neointimal formation surrounding Zn wires, and macrophage infiltration and extracellular matrix (ECM) remodeling in the neointimas were examined. Results In vitro data showed that the PDA-coated Zn encouraged EC adhesion, spreading, proliferation, and phenotype maintenance on its surfaces. VEGF functionalization on PDA coatings further enhanced the biocompatibility of Zn to ECs. Implantation of PDA-coated Zn wires into rat aortas didn’t cause thrombosis and showed a faster blood flow than pure Zn or the Zn wires coated with VEGF alone. In addition, the PDA coating didn’t affect the degradation of Zn wires in vivo. Besides, the PDA-coated Zn wires reduced neointimal formation, increased EC coverage, decreased macrophage infiltration, and declined aggrecan accumulation in ECM. VEGF immobilization onto PDA coatings didn’t cause thrombosis and affect Zn degradation in vivo as well, and further increased the endothelization percentage as compared to PDA coating alone, thus resulting in thinner neointimas. Conclusion These results indicate that PDA coatings with VEGF immobilization would be a promising approach to functionalize Zn surfaces to increase biocompatibility, reduce inflammation, and inhibit neointimal formation after Zn implantation in vivo.
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