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      • KCI등재

        A high-order analytical method for thick composite tubes

        Hamidreza Yazdani Sarvestani,Mehdi Hojjati 국제구조공학회 2016 Steel and Composite Structures, An International J Vol.21 No.4

        In the present paper, a new high-order simple-input analytical method is used to study thick laminated composite straight tubes subjected to combined axial force, torque and bending moment. The most general displacement field of elasticity for an arbitrary laminated composite straight tube is obtained to analytically calculate stresses under combined loadings based on a layerwise method. The accuracy of the proposed method is subsequently verified by comparing the numerical results obtained using the proposed method with finite element method (FEM) and experimental data. The results show good corresponded. The proposed method provides advantages in terms of computational time compared to FEM.

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        Evaluation of bone healing in canine tibial defects filled with cortical autograft, commercial-DBM, calf fetal DBM, omentum and omentum-calf fetal DBM

        Amin Bigham-Sadegh,Iraj Karimi,Mahsa Alebouye,Zahra Shafie-Sarvestani,Ahmad Oryan 대한수의학회 2013 JOURNAL OF VETERINARY SCIENCE Vol.14 No.3

        The present study was conducted to compare the effects of xenogenic bovine fetal demineralized bone matrix (DBM),commercial DBM, omentum, omentum-calf fetal DBM,cortical autograft and xenogenic cartilage powder on the healing of tibial defects in a dog model to determine the best material for bone healing. Seven male adult mongrel dogs,weighing 26.2 ± 2.5 kg, were used in this study. Seven holes with a diameter of 4-mm were created and then filled with several biomaterials. Radiographs were taken postoperatively on day 1 and weeks 2, 4, 6, 8. The operated tibias were removed on the 56th postoperative day and histopathologically evaluated. On postoperative days 14, 42 and 56, the lesions of the control group were significantly inferior to those in the other group (p < 0.05). On the 28th postoperative day, the autograft group was significantly superior to the control and omentum groups (p < 0.05). Moreover, calf fetal DBM was significantly superior to the control group. There was no significant difference between the histopathological sections of all groups. Overall, the omentum and omentum-DBM groups were superior to the control group, but inferior to the autograft, commercial-DBM, calf fetal DBM and calf fetal cartilage groups.

      • KCI등재

        Comparative study of ammonium transporters in different organisms by study of a large number of structural protein features via data mining algorithms

        Ehsan Tahrokh,Mansour Ebrahimi,Mahdi Ebrahimi,Fatemeh Zamansani,Narjes Rahpeyma Sarvestani,Manijeh Mohammadi-Dehcheshmeh,Mohammad Reza Ghaemi,Esmaeil Ebrahimie 한국유전학회 2011 Genes & Genomics Vol.33 No.5

        Ammonium is an excellent nitrogen source, and ammonium transfer is a fundamental process in most organisms. Membrane transport of ammonium is the key component of nitrogen metabolism mediated by Ammonium Transporter/Methylamine Permease/Rhesus (AMT/MEP/Rh) protein family. Ammonium transporters play different physiological roles in various organisms. Here, we looked at the protein characteristics of ammonium transporters in different organisms to create a link between protein characteristics and the organism. In order to increase the accuracy and precision of the employed models,for the first time, an attempt was made to cover all structural aspects of ammonium transporters in animals, bacteria, fungi,plants, and human by extracting and calculating 874 protein attributes of primary, secondary, and tertiary structures for each ammonium transporter. Then, various weighting and modeling algorithms were applied to determine how structural protein features change between organisms. Considering a large number of protein attributes made it possible to detect key protein characteristics in the structure of ammonium transporters. The results, for the first time, indicated that His-based features including count/frequency of His and frequency/count of Ile-His were the most significant features generating different types of ammonium transporters within organisms. Within different tested models, the C5.0 model was the most efficient and precise model for discrimination of organism type, based on ammonium transporter sequence, with the precision of 94.85%. The determination of protein characteristics of ammonium transporters in different organisms provides a new vista for understanding the evolution of transporters based on the modulation of protein characteristics and facilitates engineering of new transporters. In our point of view, dissecting a large number of structural protein characteristics through data mining algorithms provides a novel functional strategy for studying evolution and phylogeny. This research will serve as a basis for future studies on engineering novel ammonium transporters.

      • Correlates of Lymphedema in Women with Breast Cancer: a Case Control Study in Shiraz, Southern Iran

        Honarvar, Behnam,Sayar, Negin,Tahmasebi, Sedigheh,Zakeri, Zeinab,Talei, Asra,Rostami, Sara,Khademi, Sahar,Sarvestani, Amene Sabzi,Sekhavati, Eghbal Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup3

        Globally, the burden of breast cancer (BC) continues to increase. BC related lymphedema (BCRL) is currently non curable and as a life time risk it affects at least 25% of BC patients. Knowing more about BCRL and appropriate control of its modifiable risk factors can improve quality of life (QOL) of the affected patients. In this case control study to detect factors, 400 women with BCRL (as the case group) and 283 patients with BC without lymphedema (as the control group) that were referred to Shiraz University of Medical Sciences affiliated BC clinic center were assessed. The data were analyzed in SPSS. The mean age of the case group was $52.3{\pm}11.0years$ and of the control group was $50.1{\pm}10.9years$. In patients with BCRL, 203(50.7%) had left (Lt) side BC and in non- lymphedema group 151 (53.3%) had Lt side BC. Out of all BCRL patients, 204 (51%) had lymphedema in all parts of their affected upper extremities, 100 (25%) had swelling in the arm and forearm and 23 (5.7%) had edema in both the upper extremity and trunk. Edema, heaviness, concern about changing body image, pain and paresthesia were the most common signs/symptoms among patients with BCRL. In BCRL patients, the difference of circumference between the affected upper limb and non-affected limb was $4.4{\pm}2.5cm$ and the difference in volume displacement was $528.7{\pm}374.4milliliters$. Multiple variable analysis showed that moderate to severe activity (OR; odds ratio =14, 95% CI :2.6-73.3), invasiveness of BC (OR =13.7, 95% CI :7.3-25.6), modified radical mastectomy (OR=4.3, 95% CI :2.3-7.9), BMI =>25 (OR=4.2, 95% CI :2-8.7), radiotherapy (OR=3.9, 95% CI :1.8-8.2), past history of limb damage (OR=1.7, 95% CI :0.9-3.1) and the number of excised lymph nodes (OR=1.06, 95% CI :1.02-1.09) were the significant predictors of lymphedema in women with BC. Modifiable risk factors of BCRL such as non-guided moderate to severe physical activity, high BMI and trauma to the limb should be controlled as early as possible in BC patients to prevent development of BCRL and improve QOL of these patients.

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